エキソデオキシリボヌクレアーゼ
- 関
- DNA exonuclease
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2018/01/03 02:49:00」(JST)
[Wiki en表示]
Exodeoxyribonucleases are both exonucleases and deoxyribonucleases. They catalyze digestion of the ends of linear DNA. They are a type of esterase. They are classified EC 3.1.11.
See also
External links
- Exodeoxyribonucleases at the US National Library of Medicine Medical Subject Headings (MeSH)
|
Hydrolase: esterases (EC 3.1)
|
3.1.1: Carboxylic
ester hydrolases |
- Cholinesterase
- Acetylcholinesterase
- Butyrylcholinesterase
- Pectinesterase
- 6-phosphogluconolactonase
- PAF acetylhydrolase
- Lipase
- Bile salt-dependent
- Gastric/Lingual
- Pancreatic
- Lysosomal
- Hormone-sensitive
- Endothelial
- Hepatic
- Lipoprotein
- Monoacylglycerol
- Diacylglycerol
|
| 3.1.2: Thioesterase |
- Palmitoyl protein thioesterase
- Ubiquitin carboxy-terminal hydrolase L1
- 4-hydroxybenzoyl-CoA thioesterase
|
| 3.1.3: Phosphatase |
- Alkaline phosphatase
- Acid phosphatase (Prostatic)/Tartrate-resistant acid phosphatase/Purple acid phosphatases
- Nucleotidase
- Glucose 6-phosphatase
- Fructose 1,6-bisphosphatase
- Protein phosphatase
- OCRL
- Pyruvate dehydrogenase phosphatase
- Fructose 6-P,2-kinase:fructose 2,6-bisphosphatase
- PTEN
- Phytase
- Inositol-phosphate phosphatase
- Protein phosphatase: Protein tyrosine phosphatase
- Protein serine/threonine phosphatase
- Dual-specificity phosphatase
|
3.1.4:
Phosphodiesterase |
- Autotaxin
- Phospholipase
- Sphingomyelin phosphodiesterase
- PDE1
- PDE2
- PDE3
- PDE4A/PDE4B
- PDE5
- Lecithinase (Clostridium perfringens alpha toxin)
- Cyclic nucleotide phosphodiesterase
|
| 3.1.6: Sulfatase |
- arylsulfatase
- Arylsulfatase A
- Arylsulfatase B
- Arylsulfatase E
- Steroid sulfatase
- Galactosamine-6 sulfatase
- Iduronate-2-sulfatase
- N-acetylglucosamine-6-sulfatase
|
Nuclease (includes
deoxyribonuclease
and ribonuclease) |
3.1.11-16:
Exonuclease |
| Exodeoxyribonuclease |
|
| Exoribonuclease |
|
|
3.1.21-31:
Endonuclease |
| Endodeoxyribonuclease |
- Deoxyribonuclease I
- Deoxyribonuclease II
- Deoxyribonuclease IV
- Restriction enzyme
- UvrABC endonuclease
|
| Endoribonuclease |
- RNase III
- RNase H
- RNase P
- RNase A
- RNase T1
- RNA-induced silencing complex
|
| either deoxy- or ribo- |
- Aspergillus nuclease S1
- Micrococcal nuclease
|
|
|
|
Enzymes
|
| Activity |
- Active site
- Binding site
- Catalytic triad
- Oxyanion hole
- Enzyme promiscuity
- Catalytically perfect enzyme
- Coenzyme
- Cofactor
- Enzyme catalysis
|
| Regulation |
- Allosteric regulation
- Cooperativity
- Enzyme inhibitor
|
| Classification |
- EC number
- Enzyme superfamily
- Enzyme family
- List of enzymes
|
| Kinetics |
- Enzyme kinetics
- Eadie–Hofstee diagram
- Hanes–Woolf plot
- Lineweaver–Burk plot
- Michaelis–Menten kinetics
|
| Types |
- EC1 Oxidoreductases (list)
- EC2 Transferases (list)
- EC3 Hydrolases (list)
- EC4 Lyases (list)
- EC5 Isomerases (list)
- EC6 Ligases (list)
|
English Journal
- Polymerase epsilon mutations and concomitant β2-microglobulin mutations in cancer.
- Voutsadakis IA1.
- Gene.Gene.2018 Mar 20;647:31-38. doi: 10.1016/j.gene.2018.01.030. Epub 2018 Jan 7.
- PMID 29320758
- RecBCD (Exonuclease V) is inhibited by DNA adducts produced by cisplatin and ultraviolet light.
- Leung WY1, Chung LH1, Kava HW1, Murray V2.
- Biochemical and biophysical research communications.Biochem Biophys Res Commun.2018 Jan 1;495(1):666-671. doi: 10.1016/j.bbrc.2017.11.060. Epub 2017 Nov 10.
- PMID 29129691
- Keeping it real: MRX-Sae2 clipping of natural substrates.
- Gnügge R1, Symington LS1.
- Genes & development.Genes Dev.2017 Dec 1;31(23-24):2311-2312. doi: 10.1101/gad.310771.117.
- PMID 29352017
Japanese Journal
- Multiple inhibitory factor removal from an Escherichia coli cell extract improves cell-free protein synthesis(ENZYMOLOGY, PROTEIN ENGINEERING, AND ENZYME TECHNOLOGY)
- Seki Eiko,Matsuda Natsuko,Kigawa Takanori
- Journal of bioscience and bioengineering 108(1), 30-35, 2009-07
- … coli strains were generated by inserting a streptavidin binding peptide (SBP) tag sequence at the 3' termini of the genes encoding polynucleotide phosphorylase (PNPase) and/or Exodeoxyribonuclease V alpha chain (RecD) on the chromosomal DNA. …
- NAID 110007359705
Related Links
- Exodeoxyribonuclease information including symptoms, causes, diseases, symptoms, treatments, and other medical and health issues. ... Introduction: Exodeoxyribonuclease Description of Exodeoxyribonuclease ...
- 5'-exonucleolytic degradation of double-stranded (ds) DNA. Can also cleave bifurcated nucleic acids such as flap and pseudo-Y substrates in a structure-specific manner. This requires free 5' single-stranded (ss) ends and cleaves at ...
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