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a naturally occurring estrogenic hormone; a synthetic form is used to treat estrogen deficiency (同)oestriol

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2018/08/29 21:52:54」(JST)

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Estriol tripropionate (brand name Estriel), or estriol tripropanoate, is an estrogen medication.^[1] It is an estrogen ester, specifically, an ester of estriol.^[1]

References

^ ^a ^b J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 899. ISBN 978-1-4757-2085-3.

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1. ダウン症の母体血清スクリーニングに関する臨床検査の問題laboratory issues related to maternal serum screening for down syndrome [show details]
…at 15 to 18 weeks of gestation). Four markers are measured: Alpha fetoprotein (AFP) Unconjugated estriol (uE3) Total/intact human chorionic gonadotropin (hCG) or the free beta subunit of hCG (free beta) …
2. 閉経関連性器尿路症候群（外陰腟萎縮症）の治療treatment of genitourinary syndrome of menopause vulvovaginal atrophy [show details]
…progestin and/or endometrial assessment. Estriol – Estriol vaginal cream and suppositories are available in many countries outside the United States . Estriol is the 16-hydroxylated metabolite of estradiol …
3. 副腎アンドロゲン過剰症adrenal hyperandrogenism [show details]
…Pregnant women who have placental aromatase or sulfatase deficiency are unable to produce estradiol and estriol from their precursors, DHEA sulfate and 16-alpha-DHEA sulfate, which come from the fetus . Mothers …
4. 自然早産の病因pathogenesis of spontaneous preterm birth [show details]
…directly . The placenta converts these androgen precursors to estrone (E1), estradiol (E2), and estriol (E3), which, in the presence of estrogen receptor-alpha (ER-alpha), activate the myometrium by increasing …
5. ダウン症候群およびトリソミー18のスクリーニングのための、妊娠初期のcombined testおよびintegrated testfirst trimester combined test and integrated tests for screening for down syndrome and trisomy 18 [show details]
…serum sample is drawn and the quadruple test markers are run (alpha fetoprotein [AFP], unconjugated estriol [uE3], inhibin A and beta-hCG) Beta-hCG can be used as a marker in either the first or second trimester…

English Journal

[Clinical effects of estriol tripropionate for menopausal problems--a double blind study].

Tojo S, Kanazawa S, Taoka M, Kiyoshige K, Kitagaki S.
Horumon to rinsho. Clinical endocrinology. 1975 Apr;23(4)357-65.
PMID 1098813

[Clinical effects of estriol tripropionate in postsurgical ovarian dysfuntion--a study by a double-blind method].

Tojo S, Kanazawa S, Tomita K.
Horumon to rinsho. Clinical endocrinology. 1975 Mar;23(3)237-42.
PMID 1102154

[CLINICAL EXPERIENCES WITH ESTRIOL TRIPROPIONATE ON CLIMACTERIC DISORDERS].

, U U, Y Y, Y Y.
Fukuoka igaku zasshi = Hukuoka acta medica. 1964 Aug;55()615-7.
PMID 14211945

Japanese Journal

二重盲検法によるEstriol tripropionateの更年期障害に対する臨床効果

東条伸平 [他]
ホルモンと臨床 23(4), p357-365, 1975-04
NAID 40003550301

二重盲検法によるEstriol tripropionateの術後卵巣機能欠落症に対する臨床効果

東条伸平,金沢精一,富田謙吉
ホルモンと臨床 23(3), p237-242, 1975-03
NAID 40003550335

Estrogenの性腺抑制作用とその臨床応用について

吉川光夫
日本産科婦人科学会雑誌 18(11), 1283-1292, 1966-11
… Estrogenの発情作用についてはDD系去勢成熟マウスを用いEstradioldipropionate, Estriol, Estriol tripropionateの比は40:2:1の割合であることを認めた. …
NAID 110002125151

「estriol benzoate diacetate」

Estriol tripropionate
Clinical data
Trade names	Estriel
Synonyms	Oestriol tripropionate; Estriol tripropanoate
Routes of; administration	Intramuscular injection
Drug class	Estrogen; Estrogen ester
Identifiers
	IUPAC name [(8R,9S,13S,14S,16R,17R)-13-methyl-3,17-di(propanoyloxy)-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-16-yl] propanoate;
CAS Number	2236-31-9;
PubChem CID	102232;
ChemSpider	92362;
UNII	S2A0P1AFQ9;
Chemical and physical data
Formula	C27H36O6
Molar mass	456.579 g/mol
3D model (JSmol)	Interactive image;
	SMILES CCC(=O)O[C@@H]1C[C@H]2[C@@H]3CCc4cc(OC(=O)CC)ccc4[C@H]3CC[C@]2(C)[C@H]1OC(=O)CC;
	InChI InChI=1S/C27H36O6/c1-5-23(28)31-17-9-11-18-16(14-17)8-10-20-19(18)12-13-27(4)21(20)15-22(32-24(29)6-2)26(27)33-25(30)7-3/h9,11,14,19-22,26H,5-8,10,12-13,15H2,1-4H3/t19-,20-,21+,22-,26+,27+/m1/s1; Key:ONMZMZJEZHMWQL-REUUDLSRSA-N;