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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/05/21 22:08:05」(JST)

Epitiostanol is an anabolic steroid.

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English Journal

Determination of mepitiostane metabolites in human urine by liquid chromatography/tandem mass spectrometry for sports drug testing.

Okano M1, Sato M2, Kojima A2, Kageyama S2.
Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.2015 Nov 10;115:236-44. doi: 10.1016/j.jpba.2015.07.016. Epub 2015 Jul 23.
Mepitiostane (2α,3α-epithio-17β-(1-methoxycyclopentyloxy)-5α-androstane), which is a prodrug of epitiostanol (2α,3α-epitio-5α-androstane-17β-ol), is an epitiosteroid having anti-estrogenic and weak androgenic anabolic activities. The World Anti-Doping Agency prohibits the misuse of mepitiost
PMID 26247800

Estrogen-depleted condition induces apoptosis of rat mammary cancer cells after entering the S-phase of the cell cycle.

Watanabe Y1, Sawada N, Isomura H, Satoh H, Hirata K, Mori M.
Cell structure and function.Cell Struct Funct.1995 Apr;20(2):125-32.
To elucidate the relationship of estrogen-depleted condition to apoptosis and tumor regression, 7,12-dimethylbenz[a]anthracene-induced mammary cancers of Sprague-Dawley rats were ovariectomized or treated with the anti-estrogenic agent epitiostanol after which proliferative activity and the incidenc
PMID 7641294

Factors determining the intrinsic lymphatic partition rate of epitiostanol and mepitiostane.

Ichihashi T1, Takagishi Y, Yamada H.
Pharmaceutical research.Pharm Res.1992 Dec;9(12):1617-21.
Substitution of the steroid epitiostanol (EP) at position 17 with methoxycyclopentane yields the extremely liophilic mepitiostane (MP) with preferential partitioning into the lymph. Most of the MP in the lymph was associated with the core lipids of chylomicrons and very low-density lipoproteins (VLD
PMID 1488406

Estrogen-Depleted Condition Induces Apoptosis of Rat Mammary Cancer Cells after Entering the S-phase of the Cell Cycle

Estrogen-Depleted Condition Induces Apoptosis of Rat Mammary Cancer Cells after Entering the S-phase of the Cell Cycle.

リンク元	「エピチオスタノール」

Epitiostanol
Names
	Other names Thiodrol; 2,3-Epithioandrostan-17-ol
Identifiers
CAS Registry Number	2363-58-8
Jmol-3D images	Image
PubChem	3243
	SMILES C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4[C@@]3(C[C@@H]5[C@H](C4)S5)C ;
Properties
Molecular formula	C19H30OS
Molar mass	306.51 g·mol−1
	Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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	Infobox references