WordNet

DNA that is not incorporated into the genome but is replicated together with the genome (especially in bacterial cells)

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

Martinez-Picado J1, Deeks SG.
Current opinion in HIV and AIDS.Curr Opin HIV AIDS.2016 Jul;11(4):417-23. doi: 10.1097/COH.0000000000000287.
PURPOSE OF REVIEW: The present review will highlight some of the recent findings regarding the capacity of HIV-1 to replicate during antiretroviral therapy (ART).RECENT FINDINGS: Although ART is highly effective at inhibiting HIV replication, it is not curative. Several mechanisms contribute to HIV
PMID 27078619

Enhanced Generation of Integration-free iPSCs from Human Adult Peripheral Blood Mononuclear Cells with an Optimal Combination of Episomal Vectors.

Wen W1, Zhang JP1, Xu J1, Su RJ2, Neises A2, Ji GZ1, Yuan W1, Cheng T3, Zhang XB4.
Stem cell reports.Stem Cell Reports.2016 Jun 14;6(6):873-84. doi: 10.1016/j.stemcr.2016.04.005. Epub 2016 May 5.
We previously reported the generation of integration-free induced pluripotent stem cells from adult peripheral blood (PB) with an improved episomal vector (EV) system, which uses the spleen focus-forming virus U3 promoter and an extra factor BCL-XL (B). Here we show an ∼100-fold increase in effici
PMID 27161365

Vergnes B1, Gazanion E2, Grentzinger T2.
Molecular and biochemical parasitology.Mol Biochem Parasitol.2016 Jun 10. pii: S0166-6851(16)30076-7. doi: 10.1016/j.molbiopara.2016.06.004. [Epub ahead of print]
SIR2 proteins are NAD+-dependent deacetylases involved in epigenetic control of gene expression and metabolic regulation through post-translational modification of diverse target proteins. In pathogens, these enzymes are considered as attractive drug targets involved in key aspects of the infectious
PMID 27297183

Kamiya Hiroyuki,Suzuki Tetsuya,Harashima Hideyoshi
Genes and environment : the official journal of the Japanese Environmental Mutagen Society 36(2), 65-68, 2014-05
NAID 40020073386

APOBEC3 deaminases induce hypermutation in human papillomavirus 16 DNA upon beta interferon stimulation

Wang Zhe,Wakae Kousho,Kitamura Kouichi,Aoyama Satoru,Liu Guangyan,Koura Miki,Monjurul Ahasan M.,Kukimoto Iwao,Muramatsu Masamichi
Journal of Virology 88(2), 1308-1317, 2014-01
… Here we examined the involvement of A3s in the HPV life cycle using cervical keratinocyte W12 cells, which are derived from low-grade lesions and retain episomal HPV16 genomes in their nuclei. …
NAID 120005368221

中野真由子,種村篤,小泉佳奈,横見明典,片山一朗,中西元,田中俊宏,関本貢嗣
皮膚の科学 13(4), 263-268, 2014
… さらに，HPV ウイルスの integration の有無を APOT (amplification of papillomavirus oncogene transcript) 法にて検討したところ，メッセンジャー RNA の integration が確認されず，最終的に episomal form の HPV16 感染を認めた Bowen 病と診断した。 …
NAID 130004706611