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English Journal

Empirical Study of an Adaptive Multiscale Model for Simulating Cardiac Conduction.

Hand PE, Griffith BE.SourceLeon H. Charney Division of Cardiology, New York University School of Medicine, New York, NY, 10016, USA, hand@cims.nyu.edu.
Bulletin of mathematical biology.Bull Math Biol.2011 Apr 30. [Epub ahead of print]
We modify and empirically study an adaptive multiscale model for simulating cardiac action potential propagation along a strand of cardiomyocytes. The model involves microscale partial differential equations posed over cells near the action potential upstroke and macroscale partial differential equa
PMID 21533664

Anastassiou CA, Perin R, Markram H, Koch C.SourceDivision of Biology, California Institute of Technology, Pasadena, California, USA. costas@caltech.edu
Nature neuroscience.Nat Neurosci.2011 Feb;14(2):217-23. Epub 2011 Jan 16.
The electrochemical processes that underlie neural function manifest themselves in ceaseless spatiotemporal field fluctuations. However, extracellular fields feed back onto the electric potential across the neuronal membrane via ephaptic coupling, independent of synapses. The extent to which such ep
PMID 21240273