WordNet

(biology) any agency bringing about activation; a molecule that increases the activity of an enzyme or a protein that increases the production of a gene product in DNA transcription
any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions

PrepTutorEJDIC

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/07/10 19:17:44」(JST)

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 急性心筋梗塞におけるアンギオテンシン変換酵素阻害剤：作用機序 angiotensin converting enzyme inhibitors in acute myocardial infarction mechanisms of action
2. 血管内皮機能および血栓溶解療法の基本的メカニズム vascular endothelial function and fundamental mechanisms of fibrinolysis thrombolysis
3. 止血の概要 overview of hemostasis
4. 心不全におけるアンギオテンシン変換酵素阻害剤およびアンギオテンシン受容体拮抗剤：作用機序 angiotensin converting enzyme inhibitors and receptor blockers in heart failure mechanisms of action
5. レニン－アンギオテンシン系の概要 overview of the renin angiotensin system

Effects of astaxanthin on blood coagulation, fibrinolysis and platelet aggregation in hyperlipidemic rats.

Deng ZY1,2, Shan WG1, Wang SF1, Hu MM1, Chen Y1.
Pharmaceutical biology.Pharm Biol.2017 Dec;55(1):663-672.
CONTEXT: Astaxanthin (ASTX) is a xanthophyll carotenoid that reduces hemostasis in hyperlipidemic organisms. Its antihemostatic mechanisms remain unclear.OBJECTIVE: The effects of ASTX on coagulation, the fibrinolytic system and platelet aggregation were investigated in hyperlipidemic rats.MATERIALS
PMID 27951728

Hydroxytyrosol targets extracellular matrix remodeling by endothelial cells and inhibits both ex vivo and in vivo angiogenesis.

García-Vilas JA1, Quesada AR1, Medina MÁ2.
Food chemistry.Food Chem.2017 Apr 15;221:1741-1746. doi: 10.1016/j.foodchem.2016.10.111. Epub 2016 Oct 24.
The health benefits of olive oil are attributed to their bioactive compounds, such as hydroxytyrosol. Previously, we demonstrated that hydroxytyrosol inhibits angiogenesis in vitro. The present study aimed to: i) get further insight into the effects of hydroxytyrosol on extracellular matrix remodeli
PMID 27979155

DGKζ Downregulation Enhances Osteoclast Differentiation and Bone Resorption Activity Under Inflammatory Conditions.

Iwazaki K1,2, Tanaka T1, Hozumi Y1, Okada M1, Tsuchiya R1, Iseki K3, Topham MK4, Kawamae K5, Takagi M2, Goto K1.
Journal of cellular physiology.J Cell Physiol.2017 Mar;232(3):617-624. doi: 10.1002/jcp.25461. Epub 2016 Jun 30.
Bone homeostasis is maintained by a balance between resorption of the bone matrix and its replacement by new bone. Osteoclasts play a crucially important role in bone metabolism. They are responsible for bone resorption under pathophysiological conditions. Differentiation of these cells, which are d
PMID 27312515

Masaru Yanagihashi,Kiyokazu Kawabe,Ken Ikeda
Toho Journal of Medicine 1(1), 2-6, 2015-03
… The activity of signal transducer and activator of transcription 3 (STAT3) was analyzed in naïve T cells, using enzyme-linked immunosorbent assays after stimulation with the above cytokines for 30 min. Results: Th17 cell differentiation was significantly inhibited by ibudilast. …
NAID 120005614751

池脇信直,園田徹,土井宏太郎 [他],大野英治
九州保健福祉大学研究紀要 16, 121-128, 2015-03
ヒト血管内皮前駆細胞(Human endothelial progenitor cells :HEPCs)から分泌される可溶性CD93(sCD93)分子の動態を自主開発した抗ヒトCD93 抗体(mNI-11)を用いて解析した。HEPCs は低濃度であるが、sCD93 分子を培養液中に自然分泌していることがわかった。HEPCs をPKC 活性剤であるPMAで処理したところ、sCD93 分子の分泌は有 …
NAID 110009912282

Zou Lei,Ke Lu,Wu Congye [他],Tong Zhihui,Li Weiqin,Li Ning,Li Jieshou
Biological and Pharmaceutical Bulletin 38(7), 1012-1019, 2015
… Furthermore, the expression of signal transducer and activator of transcription (STAT) 3 and phospho-STAT3 (p-STAT3) in the pancreas was also evaluated. … The results revealed that the administration of SEW2871 ameliorated the severity of AP, by a reduction of serum pancreatic enzyme activity and levels of cytokines, decreased pancreatic MPO activity, depletion of CD4+CD45+ T lymphocytes in the blood and a reduction of CD4+ T cell infiltration in the pancreas. …
NAID 130005086280