English Journal

Schlafen 3 Mediates the Differentiating Effects of Cdx2 in Rat IEC-Cdx2L1 Enterocytes.

Walsh MF1, Hermann R, Lee JH, Chaturvedi L, Basson MD.
Journal of investigative surgery : the official journal of the Academy of Surgical Research.J Invest Surg.2015 Aug;28(4):202-7.
AIM: Mature, differentiated enterocytes are essential for normal gut function and critical to recovery from pathological conditions. Little is known about the factors that regulate intestinal epithelial cell differentiation in the adult intestine. The transcription factor, Cdx2, involved in enterocy
PMID 26268420

IGF-1 decreases portal vein endotoxin via regulating intestinal tight junctions and plays a role in attenuating portal hypertension of cirrhotic rats.

Zhao TY1, Su LP2, Ma CY3, Zhai XH4, Duan ZJ5, Zhu Y6, Zhao G7, Li CY8, Wang LX9, Yang D10.
BMC gastroenterology.BMC Gastroenterol.2015 Jul 8;15:77. doi: 10.1186/s12876-015-0311-5.
BACKGROUND: Intestinal barrier dysfunction is not only the consequence of liver cirrhosis, but also an active participant in the development of liver cirrhosis. Previous studies showed that external administration of insulin-like growth factor 1 (IGF-1) improved intestinal barrier function in liver
PMID 26152281

Histone Deacetylase Inhibition Impairs Normal Intestinal Cell Proliferation and Promotes Specific Gene Expression.

Roostaee A1,2, Guezguez A1,2, Beauséjour M2, Simoneau A1, Vachon PH2, Levy E3, Beaulieu JF1,2.
Journal of cellular biochemistry.J Cell Biochem.2015 Jun 30. doi: 10.1002/jcb.25274. [Epub ahead of print]
Mechanisms that maintain proliferation and delay cell differentiation in the intestinal crypt are not yet fully understood. We have previously shown the implication of histone methylation in the regulation of enterocytic differentiation. In this study, we investigated the role of histone deacetylati
PMID 26129821

Japanese Journal

Chromatin Structure with Respect to Histone Signature Changes during Cell Differentiation

Harničarová Horáková Andrea,Bártová Eva,Kozubek Stanislav
Cell Structure and Function 35(1), 31-44, 2010
… The functional relevance of nuclear architecture and epigenetic traits is preferentially discussed in the context of in vitro induced enterocytic differentiation and pluripotent or differentiated embryonic stem cells. …
NAID 130004053873