エンドゼピン
- 関
- diazepam binding inhibitor
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/03/16 17:13:28」(JST)
[Wiki en表示]
Endozepines are endogenous compounds with benzodiazepine like effects. They have been linked to hepatic encephalopathy and have controversially been linked to some cases of recurrent stupor.[1] Initially, the key diagnostic test is stupor which is sensitive to the benzodiazepine receptor antagonist flumazenil in the absences of exogenous benzodiazepines.
Potential candidates for these compounds are:[2]
- oleamides
- nonpeptidic endozepines
- the protein Diazepam binding inhibitor (DBI)
References
- ^ Cortelli, P.; Avallone, R.; Baraldi, M.; Zeneroli, ML.; Mandrioli, J.; Corsi, L.; Riva, R.; Tinuper, P.; et al. (Dec 2005). "Endozepines in recurrent stupor". Sleep Med Rev 9 (6): 477–87. doi:10.1016/j.smrv.2005.07.003. PMID 16233983.
- ^ Farzampour, Z; Reimer, RJ; Huguenard, J (2015). "Endozepines.". Advances in pharmacology (San Diego, Calif.) 72: 147–64. doi:10.1016/bs.apha.2014.10.005. PMID 25600369.
English Journal
- The Role of 18 kDa Mitochondrial Translocator Protein (TSPO) in Programmed Cell Death, and Effects of Steroids on TSPO Expression.
- Veenman L, Gavish M.SourceDepartment of Molecular Pharmacology, Rappaport Family Institute for Research in the Medical Sciences, Technion-Israel Institute of Technology, P.O. Box 9649, Bat-Galim, Haifa 31096, Israel. mgavish@tx.technion.ac.il.
- Current molecular medicine.Curr Mol Med.2012 May 1;12(4):398-412.
- The mitochondrial 18 kDa Translocator Protein (TSPO) was first detected by its capability to bind benzodiazepines in peripheral tissues and later also in glial cells in the brain, hence its previous most common name peripheral benzodiazepine receptor (PBR). TSPO has been implicated in various functi
- PMID 22348610
- Genetic epistasis in female suicide attempters: Interaction between genes of monoaminergic and GABAergic system.
- Fernandez-Navarro P, Vaquero-Lorenzo C, Blasco-Fontecilla H, Diaz-Hernández M, Fernández Piqueras J, Saiz-Ruiz J, Baca-Garcia E.SourceCancer and Environmental Epidemiology Unit, National Centre for Epidemiology, Carlos III Institute of Health, Avda. Monforte de Lemos, 5, 28029 Madrid, Spain; CIBER en Epidemiología y Salud Pública (CIBERESP), Spain.
- Progress in neuro-psychopharmacology & biological psychiatry.Prog Neuropsychopharmacol Biol Psychiatry.2012 Apr 23. [Epub ahead of print]
- BACKGROUND: Complex behaviors such as suicidal behavior likely exhibit gene-gene interactions. The main aim of this study is to explore potential single nucleotide polymorphisms combinations with epistatic effect in suicidal behavior using a data mining tool (Multifactor Dimensionality Reduction).ME
- PMID 22554588
Japanese Journal
- DIAZEPAM-BINDING INHIBITOR-DERIVED PEPTIDES-INDUCED ANOREXIGENIC ACTION IS MEDIATED THROUGH THE METABOTROPIC ENDOZEPINE RECEPTOR IN GOLDFISH
- WADA Kohei,MIURA Tohru,MARUYAMA Keisuke,SHIMAKURA Sei-Ichi,UCHIYAMA Minoru,LEPRINCE Jerome,TONON Marie-Christine,VAUDRY Hubert,MATSUDA Kouhei
- Proceedings of the Japan Society for Comparative Endocrinology (22), 28, 2007-10-12
- NAID 10020188373
- Endozepine stupor : recurring stupor linked to endozepine-4 accumulation
Related Links
- endozepine (en-dōz-a-pēn), An endogenous ligand for the benzodiazepine receptor. ... Signalling receptors including cytokine and hormone receptors, and signalling ligands 1A12 2e-13 1744840 FMRF amide Pond snail 1C5 4e-7 ...
- endozepine.com e-mail info@endozepine.com endozepine.com e-mail info@endozepine.com ...
★リンクテーブル★
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- endozepine
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- ジアゼパム結合阻害タンパク質
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ジアゼパム結合阻害タンパク質
- 関
- endozepine