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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/05/28 15:09:10」(JST)

English Journal

Tissue-nonspecific alkaline phosphatase as a target of sFRP2 in cardiac fibroblasts.

Martin S1, Lin H1, Ejimadu C1, Lee T2.
American journal of physiology. Cell physiology.Am J Physiol Cell Physiol.2015 Aug 1;309(3):C139-47. doi: 10.1152/ajpcell.00009.2015. Epub 2015 May 13.
Recent studies of myocardial infarction in secreted Frizzled-related protein 2 (sFRP2) knockout mice and our hamster heart failure therapy based on sFRP2 blockade have established sFRP2 as a key profibrotic cytokine in the heart. The failing hamster heart is marked by prominent fibrosis and calcific
PMID 25972450

Quinazoline-4-piperidine sulfamides are specific inhibitors of human NPP1 and prevent pathological mineralization of valve interstitial cells.

Shayhidin EE1, Forcellini E2, Boulanger MC1, Mahmut A1, Dautrey S2, Barbeau X3, Lagüe P3, Sévigny J4,5, Paquin JF2, Mathieu P1.
British journal of pharmacology.Br J Pharmacol.2015 Aug;172(16):4189-99. doi: 10.1111/bph.13204. Epub 2015 Jul 8.
BACKGROUND AND PURPOSE: Ectonucleotide pyrophosphatase/PDE1 (NPP1) is an ectoenzyme, which plays a role in several disorders including calcific aortic valve disease (CAVD). So far, compounds that have been developed as inhibitors of NPP1 lack potency and specificity. Quinazoline-4-piperidine sulfami
PMID 26031197

60 YEARS OF NEUROENDOCRINOLOGY: TRH, the first hypophysiotropic releasing hormone isolated: control of the pituitary-thyroid axis.

Joseph-Bravo P1, Jaimes-Hoy L2, María Uribe R2, Charli JL2.
The Journal of endocrinology.J Endocrinol.2015 Aug;226(2):T85-T100. doi: 10.1530/JOE-15-0124. Epub 2015 Jun 22.
This review presents the findings that led to the discovery of TRH and the understanding of the central mechanisms which control hypothalamus-pituitary-thyroid axis (HPT) activity. The earliest studies on thyroid physiology are now dated a century ago when basal metabolic rate was associated with th
PMID 26101376