WordNet
- an inactive substance that is a vehicle for a radioactive tracer of the same substance and that assists in its recovery after some chemical reaction
- (genetics) an organism that possesses a recessive gene whose effect is masked by a dominant allele; the associated trait is not apparent but can be passed on to offspring
- a rack attached to a vehicle; for carrying luggage or skis or the like
- a self-propelled wheeled vehicle designed specifically to carry something; "refrigerated carriers have revolutionized the grocery business"
- someone whose employment involves carrying something; "the bonds were transmitted by carrier" (同)bearer, toter
- a person or firm in the business of transporting people or goods or messages (同)common_carrier
- (medicine) a person (or animal) who has some pathogen to which he is immune but who can pass it on to others (同)immune carrier
- a boy who delivers newspapers (同)newsboy
- use recreational drugs (同)do drugs
- administer a drug to; "They drugged the kidnapped tourist" (同)dose
- a substance that is used as a medicine or narcotic
PrepTutorEJDIC
- 『運搬する人』;輸送業者(会社) / 運搬する物,運客車;運客設備 / (…の)媒介体,保菌者《+『of』+『名』》 / (また『aircraft carrier』)航空母艦 / (自転車・車の)荷台
- 『薬』,薬品,薬剤 / 『麻薬』,麻酔剤 / 〈人〉‘に'薬(特に麻酔剤)を与える / 〈飲食物〉‘に'(麻酔薬・毒薬などの)薬を混ぜる
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2012/07/21 16:08:12」(JST)
[Wiki en表示]
Drug carriers are substances that serve as mechanisms to improve the delivery and the effectiveness of drugs. Drug carriers are used in sundry drug delivery systems such as:
- controlled-release technology to prolong in vivo drug actions;
- decrease drug metabolism, and
- reduce drug toxicity.
Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions.
Contents
- 1 Examples
- 2 See also
- 3 Resources
- 4 References
- 5 External links
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Examples
Carriers which are able to biodegrade include:
- Liposomes;
- Microspheres made of the biodegradable polymer poly(lactic-co-glycolic) acid
- albumin microspheres;
- synthetic polymers (soluble);
- nanofibers;[1]
- Protein-DNA complexes;
- protein conjugates;
- erythrocytes
- virosomes
See also
- Bioavailability
- Drug design
- Nanoparticle
Resources
The following research papers from IUPAC are in pdf format:
- Biodegradable hydrogels for bone regeneration through growth factor release
- Development of acid-sensitive copolymer micelles for drug delivery
References
- ^ Nagy ZK; Balogh A, Vajna B, Farkas A, Patyi G, Kramarics A, Marosi G (2011). "Comparison of Electrospun and Extruded Soluplus-Based Solid Dosage Forms of Improved Dissolution". Journal of Pharmaceutical Sciences. DOI:10.1002/jps.22731.
External links
- Weighting cancer drugs to make them hit tumors harder PhysOrg.com article
- Designing Better Cancer Drugs Provides insight into carrier molecules' functionality which may yield safer cancer treatments.
UpToDate Contents
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English Journal
- Drug-in-cyclodextrin-in-liposomes as a carrier system for volatile essential oil components: Application to anethole.
- Gharib R1, Auezova L2, Charcosset C3, Greige-Gerges H4.
- Food chemistry.Food Chem.2017 Mar 1;218:365-371. doi: 10.1016/j.foodchem.2016.09.110. Epub 2016 Sep 17.
- A combined approach based on cyclodextrin/drug inclusion complex formation and loading into liposomes was applied to improve the effectiveness of liposome loading with essential oils. Hydroxypropyl-β-cyclodextrin/ANE (HP-β-CD/ANE) inclusion complexes were prepared and encapsulated into liposomes (
- PMID 27719922
- Palm olein-in-water Pickering emulsion stabilized by Fe3O4-cellulose nanocrystal nanocomposites and their responses to pH.
- Low LE1, Tey BT2, Ong BH3, Chan ES4, Tang SY5.
- Carbohydrate polymers.Carbohydr Polym.2017 Jan 2;155:391-399. doi: 10.1016/j.carbpol.2016.08.091. Epub 2016 Aug 29.
- We studied the formation of palm olein-in-water (O/W) Pickering emulsion stabilized by Fe3O4-cellulose nanocrystals (MCNC) nanocomposites obtained by ultrasound assisted in-situ co-precipitation method. The synthesized MCNC nanocomposites successfully stabilized Pickering emulsion with dual response
- PMID 27702526
- In vitro release of metformin hydrochloride from sodium alginate/polyvinyl alcohol hydrogels.
- Martínez-Gómez F1, Guerrero J2, Matsuhiro B3, Pavez J2.
- Carbohydrate polymers.Carbohydr Polym.2017 Jan 2;155:182-191. doi: 10.1016/j.carbpol.2016.08.079. Epub 2016 Aug 26.
- Hydrogels, based on polysaccharides have found a number of applications as drug delivery carriers. In this work, hydrogels of full characterized sodium alginate (Mn 87,400g/mol) and commercial poly(vinyl alcohol) (PVA) sensitive to pH and temperature stimuli were obtained using a simple, controlled,
- PMID 27702502
Japanese Journal
- Aerosol Delivery of siRNA to the Lungs. Part 2: Nanocarrier-based Delivery Systems
- Fabrication of Fucoxanthin-Loaded Microsphere(F-LM) By Two Steps Double-Emulsion Solvent Evaporation Method and Characterization of Fucoxanthin before and after Microencapsulation
- Preparation and Characterization of SN-38-Encapsulated Phytantriol Cubosomes Containing α-Monoglyceride Additives
Related Links
- This website is for those who try to develop for Microsphere drug carrier / drug delivery system ... 652, Fukano, Muro, Uda City Nara 632-0203, Japan TEL +81-745-97-2111 FAX +81-745-97-2112 E-mail: info@venture-chemical.co.jp
- Therapeutic uses of a variety of drug carrier systems have significant impact on the treatment and potential cure of many chronic diseases, including cancer, diabetes mellitus, psoriasis, parkinsons, Alzheimer, rheumatoid arthritis ...
Related Pictures
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