プロピオン酸ドロスタノロン
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/07/20 18:56:12」(JST)
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Dromostanolone
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| Systematic (IUPAC) name |
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(2R,5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-2,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
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| Clinical data |
Pregnancy
category |
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| Legal status |
- CA: Schedule IV
- US: Schedule III
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Routes of
administration |
Intramuscular injection or transdermal cream |
| Pharmacokinetic data |
| Bioavailability |
Oral 0-2%, Intramuscular 100% |
| Protein binding |
highly |
| Metabolism |
hepatic |
| Biological half-life |
2-3 Days |
| Excretion |
renal |
| Identifiers |
| CAS Registry Number |
58-19-5 Y |
| ATC code |
A14 |
| PubChem |
CID: 224004 |
| IUPHAR/BPS |
6947 |
| DrugBank |
DB00858 Y |
| ChemSpider |
194604 Y |
| ChEBI |
CHEBI:31523 Y |
| Chemical data |
| Formula |
C23H36O3 |
| Molecular mass |
360.53 g/mol |
SMILES
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CCC(=O)O[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(C[C@H](C(=O)C4)C)C)C
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InChI
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InChI=1S/C23H36O3/c1-5-21(25)26-20-9-8-17-16-7-6-15-12-19(24)14(2)13-23(15,4)18(16)10-11-22(17,20)3/h14-18,20H,5-13H2,1-4H3/t14-,15+,16+,17+,18+,20+,22+,23+/m1/s1 Y
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Key:NOTIQUSPUUHHEH-UXOVVSIBSA-N Y
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| Y (what is this?) (verify) |
Drostanolone propionate (trade name Masteron) is an anabolic/androgenic steroid which is the propionate ester of drostanolone. It is known to be androgenic and anabolic.[citation needed] It is incapable of aromatization and has similar properties to dihydrotestosterone.[citation needed] It has been successfully used as a breast cancer drug, but because of the high risk of virilization, safer options are prescribed.[1]
Use in sports
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This section possibly contains original research. Please improve it by verifying the claims made and adding inline citations. Statements consisting only of original research should be removed. (January 2010) |
Drostanolone is beneficial to runners and athletes who must remain in a certain weight class.[citation needed]
It has gained popularity in the bodybuilding community as a diuretic and muscle defining drug. Individuals interested in using the drostanolone propionate are those that are looking to add muscle hardness and density to their physiques, nearly always for the purpose of bodybuilding competitions.[citation needed]
Drostanolone propionate can increase muscle hardness and density, giving an individual a more complete appearance when competing on stage.[citation needed] However, an already rather low body-fat level is needed for it to take full effect.[citation needed] Drostanolone propionate can promote increased strength while keeping body fat the same or even lowering it, and can help to prevent muscle loss while dieting.[citation needed] This can also allow strength athletes or those athletes in sports which have weight classes to increase performance without the risk of being raised into a higher weight class or add mass that may hinder performance.[citation needed]
References
- ^ Chowdhury MS, Banks AJ, Bond WH, Jones WG, Ward HW (1976). "A comparison of drostanolone propionate (Masteril) and nandrolone decanoate (Deca-durabolin) in the treatment of breast carcinoma". Clin Oncol 2 (3): 203–6. PMID 103698.
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Anabolic steroids (A14)
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| Androstane (carbon 19 present) |
- Adrenosterone
- Androisoxazole
- Bolasterone (Myagen)
- Bolazine
- Boldione
- Boldenone undecylenate (Equipoise)
- 4-Chlordehydromethyltestosterone (Turinabol)
- 4-Hydroxytestosterone
- Calusterone
- Clostebol
- Danazol
- Desoxymethyltestosterone (Madol)
- DHT
- Drostanolone (Masteron)
- Enestebol
- Epitiostanol
- Fluoxymesterone (Halotestin)
- Formebolone
- Furazabol (Miotolan)
- Hydroxystenozole
- Mebolazine
- Mesabolone
- Mestanolone
- Mesterolone (Proviron)
- Methandriol
- Methandrostenolone (Dianabol)
- Metenolone
- Methenolone enanthate (Primobolan)
- Methasterone (Superdrol)
- Methyltestosterone
- Methyldiazirinol
- Oxandrolone (Anavar)
- Oxymetholone (Anadrol)
- Oxymesterone
- Prostanozol
- Quinbolone (Anabolicum Vister)
- Roxibolone
- Silandrone
- Stanozolol (Strombafort
- Winstrol)
- Stenbolone
- Testosterone`s (Sustamed
- Sustanon)
- 1-Testosterone
- Thiomesterone
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| Estrene (carbon 19 absent) |
- Bolenol
- Ethyldienolone
- Ethylestrenol
- Mibolerone (Cheque Drops)
- Methylnortestosterone
- Metribolone (R1881)
- Nandrolone (Deca Durabolin)
- Norboletone (Genabol)
- Norclostebol
- Norethandrolone
- Normethandrone
- Oxabolone cipionate
- Propetandrol
- Tetrahydrogestrinone (The Clear)
- Trenbolone (Fina)
- Trestolone
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| Prohormones |
- 1-Androstenediol
- 1,4-Androstadienedione
- 4-Androstenediol
- 4-Androstenedione
- 19-Norandrostenediol
- 19-Norandrostenedione
- DHEA
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Index of digestion
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| Description |
- Anatomy
- Physiology
- Development
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| Disease |
- Congenital
- Neoplasms and cancer
- Inflammatory bowel disease
- Gluten sensitivity
- Other
- Symptoms and signs
- Blood tests
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| Treatment |
- Procedures
- Drugs
- anabolic steroids
- antacids
- diarrhoea and infection
- bile and liver
- functional gastrointestinal disorders
- laxatives
- peptic ulcer and reflux
- nausea and vomiting
- other
- Surgery
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UpToDate Contents
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English Journal
- The dark side of beauty: acne fulminans induced by anabolic steroids in a male bodybuilder.
- Kraus SL, Emmert S, Schön MP, Haenssle HA.
- Archives of dermatology.Arch Dermatol.2012 Oct;148(10):1210-2. doi: 10.1001/archdermatol.2012.855.
- PMID 23069972
- [Drostanolone propionate (masteril) in disseminated breast cancer in women. Immediate results].
- Marinov L, Tsekova V, Koĭnov K, Velikova M, Micheva D.
- Khirurgiia.Khirurgiia (Sofiia).1987;40(6):80-6.
- PMID 2830431
- [Diagnosis of minimal breast cancer by diagnostic hormonal treatment].
- Iwasa Z, Saeki Y, Matsunami N, Yasutomi M.AbstractAfter diagnostic hormonal treatment of 129 patients, 11 (8.5%) were revealed to have breast cancer. The diagnostic accuracy in the case of a lesion of less than 1.0 cm in diameter was 11.8% for palpation, 18.2% for mammography, 33.3% for ultrasonography; the accuracy of this method is 66.6%. Minimal breast cancer was present in eight out of nine cases. Thus, diagnostic hormonal treatment was found to be useful in the diagnosis of minimal breast cancer that coexists with mastopathy.
- Gan no rinsho. Japan journal of cancer clinics.Gan No Rinsho.1986 Apr;32(4):345-8.
- After diagnostic hormonal treatment of 129 patients, 11 (8.5%) were revealed to have breast cancer. The diagnostic accuracy in the case of a lesion of less than 1.0 cm in diameter was 11.8% for palpation, 18.2% for mammography, 33.3% for ultrasonography; the accuracy of this method is 66.6%. Minimal
- PMID 2940386
Related Links
- Used For This drug contains the active ingredient Drostanolone which is a potent synthetic androgenic/anabolic steroid similar to testosterone. It may cause an increase in the synthesis of some proteins or a decrease in the synthesis ...
- Drostanolone propionate (trade name Masteron) is an anabolic/androgenic steroid which is the propionate ester of drostanolone. It is known to be highly androgenic and mildly anabolic. ... We ask all customers to verify the legality of ...
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- drostanolone propionate