ダブルノックアウトマウス、ダブル欠損マウス、二重欠損マウス
- 関
- double knockout mouse
WordNet
- used of flowers having more than the usual number of petals in crowded or overlapping arrangements; "double chrysanthemums have many rows of petals and are usually spherical or hemispherical"
- increase twofold; "The population doubled within 50 years" (同)duplicate
- a base hit on which the batter stops safely at second base; "he hit a double to deep centerfield" (同)two-base hit, two-bagger, two-baser
- someone who closely resembles a famous person (especially an actor); "he could be Gingrichs double"; "shes the very image of her mother" (同)image, look-alike
- a stand-in for movie stars to perform dangerous stunts; "his first job in Hollywood was as a double for Clark Gable" (同)stunt man, stunt woman
- a quantity that is twice as great as another; "36 is the double of 18"
- twice as great or many; "ate a double portion"; "the dose is doubled"; "a twofold increase" (同)doubled, twofold, two-fold
- consisting of or involving two parts or components usually in pairs; "an egg with a double yolk"; "a double (binary) star"; "double doors"; "dual controls for pilot and copilot"; "duple (or double) time consists of two (or a multiple of two) beats to a measure" (同)dual, duple
- having more than one decidedly dissimilar aspects or qualities; "a double (or dual) role for an actor"; "the office of a clergyman is twofold; public preaching and private influence"- R.W.Emerson; "every episode has its double and treble meaning"-Frederick Harrison (同)dual, twofold, two-fold, treble, threefold, three-fold
- having two meanings with intent to deceive; "a sly double meaning"; "spoke with forked tongue" (同)forked
- bridge: make a demand for (a card or suit)
- do double duty; serve two purposes or have two functions; "She doubles as his wife and secretary"
- downward and forward; "he was bent double with pain"
- hit a two-base hit
- large enough for two; "a double bed"; "a double room"
- two together; "some people sleep better double"
- the syllable naming the third (mediant) note of any major scale in solmization
- increase by a factor of two; "doubling with a computer took no time at all"
- raising the stakes in a card game by a factor of 2; "I decided his double was a bluff" (同)double
- a blow that renders the opponent unconscious (同)KO, kayo
- badminton played with two players on each side
- tennis played with two players on each side
PrepTutorEJDIC
- (数量・強さ・重さ・価値などが)『2倍の』,倍の / 『二重の』,二様の;複の,対の,2人用の / 表裏のある,二心ある / (意味が)二様にとれる,あいまいな / (花が)八重の,重弁の / 『2倍に』,2倍だけ(twice) / 二重に,二様に / 対をなして,二人いっしょに / 〈U〉『2倍』[の数量・価額など] / 〈C〉2倍のもの / 〈C〉よく似た人(物),生き写し / 〈C〉(映画の)代役 / 《複数形》《単数扱い》(テニスなどの)ダブルス / 〈C〉(獲物が追っ手を逃れるときなどの)逆走,急転回 / 〈C〉2塁打 / 〈C〉(ブリッジの点の)倍加 / 〈C〉(競馬・ドッグレースの)重勝式のかけ,複式 / …‘を'『2倍にする』 / …‘を'『二つ折りにする』 / …‘の'2倍の数(量)がある / 〈二役〉‘を'ひとりで演ずる / 〈船が〉〈岬〉‘を'回る / 『2倍になる』 / (…の役を)兼ねる《+『as』+『名』》 / (急に)取って返す,逆戻りする《+『back』》 / 二つ折りになる / (ブリッジで)相手のせり高を倍加する / 2塁打を打つ
- ミ(全音階の第3音)
- (ボクシングの)ノックアウト(《略》『KO,K.O.,k.o.』) / 《話》すばらしい人(物) / ノックアウトする
UpToDate Contents
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English Journal
- Snai2 and Snai3 transcriptionally regulate cellular fitness and functionality of T cell lineages through distinct gene programs.
- Pioli PD1, Whiteside SK2, Weis JJ2, Weis JH2.
- Immunobiology.Immunobiology.2016 May;221(5):618-33. doi: 10.1016/j.imbio.2016.01.007. Epub 2016 Jan 22.
- T lymphocytes are essential contributors to the adaptive immune system and consist of multiple lineages that serve various effector and regulatory roles. As such, precise control of gene expression is essential to the proper development and function of these cells. Previously, we identified Snai2 an
- PMID 26831822
- Appl1 and Appl2 are Expendable for Mouse Development But Are Essential for HGF-Induced Akt Activation and Migration in Mouse Embryonic Fibroblasts.
- Tan Y1, Xin X2, Coffey FJ3, Wiest DL3, Dong LQ2, Testa JR1.
- Journal of cellular physiology.J Cell Physiol.2016 May;231(5):1142-50. doi: 10.1002/jcp.25211. Epub 2015 Oct 21.
- Although Appl1 and Appl2 have been implicated in multiple cellular activities, we and others have found that Appl1 is dispensable for mouse embryonic development, suggesting that Appl2 can substitute for Appl1 during development. To address this possibility, we generated conditionally targeted Appl2
- PMID 26445298
- Altered behaviour and cognitive function following combined deletion of Toll-like receptors 2 and 4 in mice.
- Too LK1, McGregor IS2, Baxter AG3, Hunt NH4.
- Behavioural brain research.Behav Brain Res.2016 Apr 15;303:1-8. doi: 10.1016/j.bbr.2016.01.024. Epub 2016 Jan 13.
- Activation of the immune system due to infection or aging is increasingly linked to impaired neuropsychological function. Toll-like receptors 2 and 4 (TLR2, TLR4) are well-characterised for their role in inflammatory events, and their combined activation has been implicated in neurological diseases.
- PMID 26774978
Japanese Journal
- Generation and characterization of severe combined immunodeficiency rats.
- Mashimo Tomoji,Takizawa Akiko,Kobayashi Junya,Kunihiro Yayoi,Yoshimi Kazuto,Ishida Saeko,Tanabe Koji,Yanagi Ami,Tachibana Asato,Hirose Jun,Yomoda Jun-Ichiro,Morimoto Shiho,Kuramoto Takashi,Voigt Birger,Watanabe Takeshi,Hiai Hiroshi,Tateno Chise,Komatsu Kenshi,Serikawa Tadao
- Cell reports 2(3), 685-694, 2012-09-27
- … 2012-09-14.Severe combined immunodeficiency (SCID) mice, the most widely used animal model of DNA-PKcs (Prkdc) deficiency, have contributed enormously to our understanding of immunodeficiency, lymphocyte development, and DNA-repair mechanisms, and they are ideal hosts for allogeneic and xenogeneic tissue transplantation. … SCID rats show several phenotypic differences from SCID mice, including growth retardation, premature senescence, and a more severe immunodeficiency without "leaky" phenotypes. …
- NAID 120004754497
- Functional Characterization of Double-knockout Mouse Sperm Lacking SPAM1 and ACR or SPAM1 and PRSS21 in Fertilization
- ZHOU Chong,KANG Woojin,BABA Tadashi
- The Journal of reproduction and development 58(3), 330-337, 2012-06-01
- … In this study, we have produced double-knockout mice lacking SPAM1 and either one of two sperm serine proteases, ACR and PRSS21, and characterized the mutant sperm. … The SPAM1/ACR- and SPAM1/PRSS21-deficient males were fertile, whereas epididymal sperm of the mutant mice exhibited a reduced capacity to fertilize the oocytes <i>in vitro</i>. …
- NAID 10030821330
- Effects of Valsartan on Fibrinolysis in Hypertensive Patients With Metabolic Syndrome : The KACT-MetS Study
- MIYATA Masaaki,IKEDA Yoshiyuki,NAKAMURA Shuji,SASAKI Takeshi,ABE Satoshi,MINAGOE Shinichi,TORII Hiroyuki,LEE Souki,TATEISHI Shigeki,KIHARA Koichi,OHBA Ichiro,KAJIYA Shoko,FURUSHO Yuko,HAMASAKI Shuichi,TEI Chuwa
- Circulation journal : official journal of the Japanese Circulation Society 76(4), 843-851, 2012-03-25
- … The animal study showed aortic PAI-1 protein expression was reduced in double knockout mice of angiotensin II type 1a receptor and apolipoprotein E (apoE) compared with the apoE knockout mice. …
- NAID 10030131024
Related Links
- Acronym Finder: dKO stands for double knockout (mice). This definition appears very rarely ... MARK HANLON, of London Road Club, landed a double knockout when he beat Bell Green's Mark White (Bell Green) 2-1 in the final and ...
- The apoE-/-/LDL-/- double knockout mice are bearing considerable structural homology to human atherosclerosis. We hypothesized, that advanced lesion formation in the renal artery is associated with kidney alterations in these ...
Related Pictures
★リンクテーブル★
[★]
- 英
- double knockout mouse、double knockout mice
- 関
- ダブルノックアウトマウス、ダブル欠損マウス
[★]
- 英
- double knockout mouse、double knockout mice
- 関
- ダブルノックアウトマウス、二重欠損マウス
[★]
- 英
- double knockout mouse、double knockout mice
- 関
- ダブル欠損マウス、二重欠損マウス
[★]
- mi-, mio-
- ?
- MI
[★]
- 同
- outlet right ventricle
[★]
- 関
- double