WordNet

a silvery soft waxy metallic element of the alkali metal group; occurs abundantly in natural compounds (especially in salt water); burns with a yellow flame and reacts violently in water; occurs in sea water and in the mineral halite (rock salt) (同)Na, atomic number 11

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Effects of diquafosol sodium eye drops on tear film stability in short but type of dry eye.

Shimazaki-Den S, Iseda H, Dogru M, Shimazaki J.SourceDepartment of Ophthalmology, Tokyo Dental College, Ichikawa General Hospital, Chiba, Japan.
Cornea.Cornea.2013 Aug;32(8):1120-5. doi: 10.1097/ICO.0b013e3182930b1d.
PURPOSE: To investigate the effects of diquafosol sodium (DQS) eye drops, a purinergic P2Y2 receptor agonist, on tear film stability in patients with unstable tear film (UTF).METHODS: Two prospective studies were conducted. One was an exploratory nonrandomized trial on 39 eyes with dry eye symptoms
PMID 23635860

Koh S, Maeda N, Ikeda C, Takai Y, Fujimoto H, Oie Y, Soma T, Tsujikawa M, Nishida K.SourceDepartment of Ophthalmology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka #E7, Suita, 565-0871, Japan.
Investigative ophthalmology & visual science.Invest Ophthalmol Vis Sci.2013 Jun 27. pii: iovs.13-12409v1. doi: 10.1167/iovs.13-12409. [Epub ahead of print]
Purpose:To investigate the effects of viscosity and suspensibility of an dry eye drop by evaluating an eye drop with one of the solutions or no solution (0.3% sodium hyaluronate ophthalmic solution, 3% diquafosol ophthalmic solution, and 2% rebamipide ophthalmic suspension) on ocular higher order-ab
PMID 23812492

A randomised, double-masked comparison study of diquafosol versus sodium hyaluronate ophthalmic solutions in dry eye patients.

Takamura E, Tsubota K, Watanabe H, Ohashi Y; Diquafosol Ophthalmic Solution Phase 3 Study Group.Collaborators (51)Kuroda A, Oura F, Kawabata H, Ideta H, Yamashita H, Shiroma H, Shimizu H, Aoki H, Mishima H, Takahashi H, Watanabe H, Takagi I, Kozaki J, Shimazaki J, Kimura K, Miyata K, Ichikawa K, Tsubota K, Kamiya K, Hayashi K, Inoue K, Sakagami K, Hirano K, Omura M, Yamaguchi M, Yamada M, Enoki M, Sakata M, Uchino M, Ishioka M, Hamada N, Kato N, Maeda N, Yokoi N, Hori S, Okamoto S, Amano S, Kimura T, Nishida T, Oshika T, Goto T, Sugiura T, Kodama T, Nakamura Y, Uchihori Y, Shimomura Y, Takahashi Y, Inoue Y, Tagawa Y, Monden Y, Komemushi S.
The British journal of ophthalmology.Br J Ophthalmol.2012 Oct;96(10):1310-5. Epub 2012 Aug 21.
AIMS: To compare the efficacy and safety of 3% diquafosol ophthalmic solution with those of 0.1% sodium hyaluronate ophthalmic solution in dry eye patients, using mean changes in fluorescein and rose bengal staining scores as endpoints. TRIAL DESIGN AND METHODS: In this multicenter, randomised, doub
PMID 22914501

CLINICAL INVESTIGATION : Diquafosol sodium ophthalmic solution for the treatment of dry eye : clinical evaluation and biochemical analysis of tear composition

Japanese journal of ophthalmology : the official international journal of the Japanese Ophthalmological Society 59(6), 415-420, 2015-11
NAID 40020653614