Eugenol, a natural phenylpropanoid derivative with possible action in biological surfaces as microbicide, anesthetic and antioxidant, was incorporated in lipid monolayers of selected lipids at the air-water interface, representing cell membrane models. Interaction of eugenol with the lipids dipalmit
Colloids and surfaces. B, Biointerfaces.Colloids Surf B Biointerfaces.2015 Dec 1;136:175-84. doi: 10.1016/j.colsurfb.2015.09.003. Epub 2015 Sep 5.
Drug-induced phospholipidosis indicates an accumulation of phospholipids within lysosomes, which can occur during therapeutic treatment. Whether or not phospholipidosis represents a toxicological phenomenon is still under investigation, and in the last decade the Food and Drug Administration has bee
Archives of biochemistry and biophysics.Arch Biochem Biophys.2015 Oct 15;584:79-89. doi: 10.1016/j.abb.2015.08.018. Epub 2015 Aug 29.
We describe the production of stable DPPC and DPPC:DPPS-proteoliposomes harboring annexin V (AnxA5) and tissue-nonspecific alkaline phosphatase (TNAP) and their use to investigate whether the presence of AnxA5 impacts the kinetic parameters for hydrolysis of TNAP substrates at physiological pH. The
Chemical & pharmaceutical bulletin 47(8), 1117-1120, 1999-08-15
… The incorporation of amphiphilic compounds, negatively charged divetylphosphate (DCP), dipalmitoylphosphatidylserine (DPPS) or positively charged dimethyldipalmitolammonium (DMDPA), into DMPC liposomal membranes enhanced protein transfer. …