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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/12/15 11:08:49」(JST)

English Journal

The influence of diuretics on the excretion and metabolism of doping agents--V. Dimefline.

Delbeke FT1, Debackere M.
Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.1991;9(1):23-8.
A sensitive method for the quantitative determination of the respiratory stimulant dimefline in 5 ml urine using capillary gas chromatography with nitrogen specific detection is presented. After the oral administration of a therapeutical amount of 16 mg dimefline to five subjects only 0.26 +/- 0.16%
PMID 2043718

Synthesis and quantitative structure-activity relationships of analeptic agents related to dimefline.

Recanatini M, Valenti P, Da Re P, Giusti P.
Archiv der Pharmazie.Arch Pharm (Weinheim).1989 May;322(5):257-61.
Some new dimefline-type derivatives have been synthesized and their pharmacological activity, as well as their distribution coefficients have been determined. The distribution coefficients of a number of previously published analogue compounds have also been measured and the QSAR analysis of the who
PMID 2569302

Huang Q, Zhang JR.
Sheng li ke xue jin zhan [Progress in physiology].Sheng Li Ke Xue Jin Zhan.1985 Oct;16(4):353-5.
PMID 3016888

リンク元	「ジメフリン」
拡張検索	「dimefline hydrochloride」

Dimefline
Systematic (IUPAC) name
	8-(dimethylaminomethyl)-7-methoxy-3-methyl-2-phenylchromen-4-one
Clinical data
AHFS/Drugs.com	International Drug Names
Legal status	?
Identifiers
CAS number	1165-48-6
ATC code	R07AB08
PubChem	CID 3078
ChemSpider	2969
UNII	9WII5M0DU3
KEGG	D07847
ChEMBL	CHEMBL519364
Chemical data
Formula	C20H21NO3
Mol. mass	323.38564 g/mol
	SMILES O=C\1c3c(O/C(=C/1C)c2ccccc2)c(c(OC)cc3)CN(C)C;
	InChI InChI=1S/C20H21NO3/c1-13-18(22)15-10-11-17(23-4)16(12-21(2)3)20(15)24-19(13)14-8-6-5-7-9-14/h5-11H,12H2,1-4H3; Key:ZXFQRFXLFWWKLX-UHFFFAOYSA-N ;
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