WordNet

convert into a sulfate
a salt or ester of sulphuric acid (同)sulphate
antibiotic consisting of a hydrogenated form of streptomycin; used against tuberculosis and tularemia and Gram-negative organisms

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/05/13 16:33:04」(JST)

Dihydrostreptomycin is an antibiotic.

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Transduction without tip links in cochlear hair cells is mediated by ion channels with permeation properties distinct from those of the mechano-electrical transducer channel.

Marcotti W1, Corns LF, Desmonds T, Kirkwood NK, Richardson GP, Kros CJ.
The Journal of neuroscience : the official journal of the Society for Neuroscience.J Neurosci.2014 Apr 16;34(16):5505-14. doi: 10.1523/JNEUROSCI.4086-13.2014.
Tip links between adjacent stereocilia are believed to gate mechano-electrical transducer (MET) channels and mediate the electrical responses of sensory hair cells. We found that mouse auditory hair cells that lack tip links due to genetic mutations or exposure to the Ca(2+) chelator BAPTA can, howe
PMID 24741041

Randomized noninferiority clinical trial evaluating 3 commercial dry cow mastitis preparations: II. Cow health and performance in early lactation.

Arruda AG1, Godden S, Rapnicki P, Gorden P, Timms L, Aly SS, Lehenbauer TW, Champagne J.
Journal of dairy science.J Dairy Sci.2013 Oct;96(10):6390-9. doi: 10.3168/jds.2013-6705. Epub 2013 Aug 16.
The objective of this randomized noninferiority clinical trial was to compare the effect of treatment with 3 different dry cow therapy formulations at dry-off on cow-level health and production parameters in the first 100 d in milk (DIM) in the subsequent lactation, including 305-d mature-equivalent
PMID 23958025

Distribution of antimicrobial-resistant lactic acid bacteria in natural cheese in Japan.

Ishihara K1, Nakajima K, Kishimoto S, Atarashi F, Muramatsu Y, Hotta A, Ishii S, Takeda Y, Kikuchi M, Tamura Y.
Microbiology and immunology.Microbiol Immunol.2013 Oct;57(10):684-91. doi: 10.1111/1348-0421.12090.
To determine and compare the extent of contamination caused by antimicrobial-resistant lactic acid bacteria (LAB) in imported and domestic natural cheeses on the Japanese market, LAB were isolated using deMan, Rogosa and Sharpe (MRS) agar and MRS agar supplemented with six antimicrobials. From 38 im
PMID 23930694

亀山勉,鍋島俊隆,伊藤治朗
日本薬理学雑誌 80(6), 525-535, 1982
… Four groups of pregnant rats were administered 200 mg/kg kanamycin sulfate (KM), 200 mg/kg dihydrostreptomycin sulfate (DHSM), 100 mg/kg neomycin sulfate (NM), or 1 ml/kg saline intramuscularly from the 10th to the 19th day of pregnancy. …
NAID 130000760450

亀山勉,鍋島俊隆,伊藤治朗
日本薬理学雑誌 77(1), 15-25, 1981
… dihydrostreptomycin sulfate, kanamycin sulfate, neomycin sulfate and ethacrynic acid. …
NAID 130000759298

矢野博,藤井溥,向秀夫,福安嗣昭,寺門誠致,伊佐山康郎
日本植物病理學會報 45(2), 201-206, 1979-04-25
… Pseudomonas lachrymansから高頻度に検出されるdihydrostreptomycin(DHSM)耐性の伝達性について検討した。 … しかしながら, acriflavine, acridine orange, ethidium bromideおよび, sodium dodecyl sulfateなどの処理によって, 耐性脱落株は得られなかった。 …
NAID 110002740016

Dihydrostreptomycin
Systematic (IUPAC) name
	2-[(1S,2R,3R,4S,5R,6R)-5-(Diaminomethylideneamino)-2-[(2R,3R,4R,5S)-3-[(2S,3S,4S,5R,6S)- 4,5-dihydroxy-6-(hydroxymethyl)-3-methylaminooxan-2-yl]oxy-4-hydroxy-4-(hydroxymethyl)- 5-methyloxolan-2-yl]oxy-3,4,6-trihydroxycyclohexyl]guanidine
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Registry Number	128-46-1
ATC code	S01AA15 QA07AA90 QJ01GA90 QJ51GA90
PubChem	CID 439369
UNII	P2I6R8W6UA
ChEMBL	CHEMBL1950576
Chemical data
Formula	C21H41N7O12
Molecular mass	583.59 g/mol
	SMILES CC1C(C(C(O1)OC2C(C(C(C(C2O)O)N=C(N)N)O)N=C(N)N)OC3C(C(C(C(O3)CO)O)O)NC)(CO)O;
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