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English Journal

Identification of a novel mitochondrial interacting protein of C1QBP using subcellular fractionation coupled with CoIP-MS.

Chen R1, Xiao M2, Gao H2, Chen Y2, Li Y2, Liu Y2, Zhang N3.
Analytical and bioanalytical chemistry.Anal Bioanal Chem.2016 Feb;408(6):1557-64. doi: 10.1007/s00216-015-9228-7. Epub 2016 Jan 11.
The study of protein-protein interactions is an essential process to understand the biological functions of proteins and the underlying mechanisms. Co-immunoprecipitation coupled with mass spectrometry (CoIP-MS) is one of the most extensively used high-throughput techniques to discover novel protein
PMID 26753982

Specific protein changes contribute to the differential muscle mass loss during ageing.

Capitanio D1,2, Vasso M3, De Palma S3, Fania C1,2, Torretta E1,2, Cammarata FP3, Magnaghi V4, Procacci P1, Gelfi C1,2,3.
Proteomics.Proteomics.2016 Feb;16(4):645-56. doi: 10.1002/pmic.201500395.
In the skeletal muscle, the ageing process is characterized by a loss of muscle mass and strength, coupled with a decline of mitochondrial function and a decrease of satellite cells. This profile is more pronounced in hindlimb than in forelimb muscles, both in humans and in rodents. Utilizing light
PMID 26698593

In recurrent primary biliary cirrhosis after liver transplantation, biliary epithelial cells show increased expression of mitochondrial proteins.

Sasaki M1, Hsu M2, Yeh MM2, Nakanuma Y3,4.
Virchows Archiv : an international journal of pathology.Virchows Arch.2015 Oct;467(4):417-25. doi: 10.1007/s00428-015-1819-3. Epub 2015 Aug 11.
In biliary epithelial lesions in primary biliary cirrhosis (PBC), mitochondrial proteins associated with deregulated autophagy are abnormally expressed. We examined whether this could be used as a diagnostic marker for end-stage PBC and recurrent PBC after liver transplantation. We examined the expr
PMID 26259963

The catalytic domain of dihydrolipoyl acetyltransferase from the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus. Expression, purification and reversible denaturation.

リンク元	「ジヒドロリポイルアセチルトランスフェラーゼ」「dihydrolipoamide acetyltransferase」
関連記事	「acetyltransferase」