dihydroergocornine

Dihydroergocornine
Names
	IUPAC name (5′a,10a)-9,10-dihydro-12′- hydroxy-2′,5′-bis(1-methylethyl) ergotaman-3′,6′,18-trione
Identifiers
CAS Number	25447-65-8 ;
3D model (JSmol)	Interactive image;
ChemSpider	147720 ;
ECHA InfoCard	100.042.705
PubChem CID	168871;
UNII	IK4C1OC8NE ;
	InChI InChI=1S/C31H41N5O5/c1-16(2)26-28(38)35-11-7-10-24(35)31(40)36(26)29(39)30(41-31,17(3)4)33-27(37)19-12-21-20-8-6-9-22-25(20)18(14-32-22)13-23(21)34(5)15-19/h6,8-9,14,16-17,19,21,23-24,26,32,40H,7,10-13,15H2,1-5H3,(H,33,37)/t19-,21-,23-,24+,26+,30-,31+/m1/s1 Key: SEALOBQTUQIVGU-QNIJNHAOSA-N ; InChI=1/C31H41N5O5/c1-16(2)26-28(38)35-11-7-10-24(35)31(40)36(26)29(39)30(41-31,17(3)4)33-27(37)19-12-21-20-8-6-9-22-25(20)18(14-32-22)13-23(21)34(5)15-19/h6,8-9,14,16-17,19,21,23-24,26,32,40H,7,10-13,15H2,1-5H3,(H,33,37)/t19-,21-,23-,24+,26+,30-,31+/m1/s1 Key: SEALOBQTUQIVGU-QNIJNHAOBI ;
	SMILES CC(C)C1C(=O)N2CCCC2C3(N1C(=O)C(O3)(C(C)C)NC(=O)C4CC5C(CC6=CNC7=CC=CC5=C67)N(C4)C)O ;
Properties
Chemical formula	C31H41N5O5
Molar mass	563.687 g/mol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	verify (what is ?)
	Infobox references

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2018/03/17 11:01:17」(JST)

Identification and human pharmacokinetics of dihydroergotoxine metabolites in man: preliminary results.

Contractile responses to ergotamine and dihydroergotamine in the perfused middle cerebral artery of rat.

Tfelt-Hansen P1, Nilsson E, Edvinsson L.
The journal of headache and pain.J Headache Pain.2007 Apr;8(2):83-9. Epub 2007 May 11.
PMID 17497262

Placebo adverse events in headache trials: headache as an adverse event of placebo.

Reuter U1, Sanchez del Rio M, Carpay JA, Boes CJ, Silberstein SD; GSK Headache Masters Program.
Cephalalgia : an international journal of headache.Cephalalgia.2003 Sep;23(7):496-503.
PMID 12950374

Hydergine (Dihydroergokryptine, Dihydroergocristine, Dihydroergocornine)の薬理作用について