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1. HIV関連末梢神経障害の疫学、臨床症状、診断、および治療 epidemiology clinical manifestations diagnosis and treatment of hiv associated peripheral neuropathy
2. HIV感染患者におけるミトコンドリア毒性の治療および予防 treatment and prevention of mitochondrial toxicity in hiv infected patients
3. HIVヌクレオシド系逆転写酵素阻害剤のミトコンドリア毒性 mitochondrial toxicity of hiv nucleoside reverse transcriptase inhibitors
4. 抗レトロウイルス療法の潜在的副作用に関するHIV感染患者を対象とした
カウンセリング counseling hiv infected patients regarding potential side effects of antiretroviral therapy
5. 発展途上国における抗レトロウイルス療法の副作用 adverse effects of antiretroviral therapy in developing countries

English Journal

Understanding the etiology and management of HIV-associated peripheral neuropathy.

Stavros K1, Simpson DM.
Current HIV/AIDS reports.Curr HIV/AIDS Rep.2014 Sep;11(3):195-201. doi: 10.1007/s11904-014-0211-2.
HIV may cause several forms of peripheral neuropathy, the most common of which is distal symmetric polyneuropathy (DSP) characterized by pain and sensory deficits in a stocking-glove distribution. The pathophysiology of DSP remains largely unknown but is thought to be related both to the neurotoxici
PMID 24969360

HBsAg seroclearance after nucleoside analogue therapy in patients with chronic hepatitis B: clinical outcomes and durability.

Kim GA, Lim YS, An J, Lee D, Shim JH, Kim KM, Lee HC, Chung YH, Lee YS, Suh DJ.
Gut.Gut.2014 Aug;63(8):1325-32. doi: 10.1136/gutjnl-2013-305517. Epub 2013 Oct 25.
OBJECTIVE: Little is known about the long-term clinical outcome and durability of HBsAg seroclearance following nucleos(t)ide analogue (NUC) therapy in patients with chronic hepatitis B (CHB).DESIGN: During a median follow-up period of 6 years (33 567 patient-years) of 5409 CHB patients who were
PMID 24162593

Telbivudine or lamivudine use in late pregnancy safely reduces perinatal transmission of hepatitis B virus in real-life practice.

Zhang H, Pan CQ, Pang Q, Tian R, Yan M, Liu X.
Hepatology (Baltimore, Md.).Hepatology.2014 Aug;60(2):468-76.
Little observational data exist describing telbivudine (LdT) or lamivudine (LAM) use in late pregnancy for preventing hepatitis B mother-to-child transmission (MTCT) in real-world settings. During the period of January 2009 to March 2011, we enrolled hepatitis B e antigen-positive mothers with HBV D
PMID 25187919

向後悟,大類洋,北濃健司,児玉栄一,満屋裕明
天然有機化合物討論会講演要旨集 (42), 835-840, 2000-10-01
… These compounds also exerted an activity against multi-dideoxynucleoside-resistant HIV-1 strains with comparable EC_<50> …
NAID 110006682042

In vitro models to predict the in vivo mechanism, rate and extent of placental transfer of dideoxynucleoside drugs against human immunodeficiency virus

Direct Transport of 2', 3'-Didehydro-3'-deoxythymidine (D4T) and Its Ester Derivatives to the Cerebrospinal Fluid via the Nasal Mucous Membrane in Rats

Yajima Toshiyuki,Juni Kazuhiko,Saneyoshi Mineo [他],HASEGAWA Tetsuya,KAWAGUCHI Takeo
Biological & pharmaceutical bulletin 21(3), 272-277, 1998-03-15
We investigated the absorption and transport of 2', 3'-didehydro-3'-deoxythymidine (D4T) and its ester prodrugs from the nasal cavity in rats. The absorption of D4T and its acetate (C2-D4T) was rapid …
NAID 110003639351