English Journal

Coupling of β1-adrenergic receptor to type 5 adenylyl cyclase and its physiological relevance in cardiac myocytes.

Tsunematsu T1, Okumura S2, Mototani Y3, Ohnuki Y3, Jin H1, Cai W1, Suita K1, Sato I1, Umemura M1, Yokoyama U1, Sato M4, Fujita T1, Ishikawa Y5.
Biochemical and biophysical research communications.Biochem Biophys Res Commun.2015 Mar 13;458(3):531-5. doi: 10.1016/j.bbrc.2015.01.149. Epub 2015 Feb 9.
Myocardial β-adrenergic receptor (β-AR) β1- and β2-subtypes are highly homologous, but play opposite roles in cardiac apoptosis and heart failure, as do cardiac adenylyl cyclase (AC) subtypes 5 (AC5) and 6 (AC6): β1-AR and AC5 promote cardiac remodeling, while β2-AR and AC6 activate cell survi
PMID 25677623

Participation of membrane adenylyl cyclase in heparin-induced capacitation in cryopreserved bovine spermatozoa.

Ricart MC1, Breininger E, Rodriguez PC, Beconi MT.
Andrologia.Andrologia.2015 Feb;47(1):30-6. doi: 10.1111/and.12218. Epub 2014 Jan 6.
The aim of this work was to study the participation of membrane adenylyl cyclase in heparin-induced capacitation in cryopreserved bovine spermatozoa. Sperm suspensions were incubated in Tyrode's albumin lactate pyruvate medium in the presence of heparin (10 IU ml(-1) ) or forskolin (1-75 μm), a wel
PMID 24387203

Hyaluronic acid as capacitation inductor: metabolic changes and membrane-associated adenylate cyclase regulation.

Fernández S1, Córdoba M.
Reproduction in domestic animals = Zuchthygiene.Reprod Domest Anim.2014 Dec;49(6):941-6. doi: 10.1111/rda.12410. Epub 2014 Sep 23.
The aim of this research was to study the effect of hyaluronic acid on bovine cryopreserved spermatozoa compared with heparin as regards the variation of capacitation induction, cellular oxidative metabolism and intracellular signal induced by membrane-associated adenylate cyclase to propose hyaluro
PMID 25251082