塩化ジデシルジメチルアンモニウム
WordNet
- any compound containing a chlorine atom
- any salt of hydrochloric acid (containing the chloride ion)
PrepTutorEJDIC
- 塩化物
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/06/30 09:26:34」(JST)
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Didecyldimethylammonium chloride
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Names |
IUPAC name
didecyl-dimethylammonium chloride
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Other names
- DDAC
- Dimethyldidecylammonium chloride[1]
- 1-Decanaminium[1]
- N-decyl-N,N-dimethyl-, chloride[1]
- Didecyldimethylammonium chloride[1]
- Didecyl dimethyl ammonium chloride[1]
- Quaternium-12[1]
Ammonium, didecyldimethyl-, chloride[1]
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Identifiers |
CAS Number
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3D model (JSmol)
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ChemSpider |
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ECHA InfoCard |
100.027.751 |
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UNII |
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InChI
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InChI=1S/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1 Y
Key: RUPBZQFQVRMKDG-UHFFFAOYSA-M Y
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InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1
Key: RUPBZQFQVRMKDG-REWHXWOFAJ
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SMILES
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[Cl-].C(CCCCC[N+](C)(CCCCCCCCCC)C)CCCC
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Properties |
Chemical formula
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C22H48ClN |
Molar mass |
362.08 g/mol |
Appearance |
liquid[2] |
Density |
0.95 g/cm3 (20 °C)[2] |
Pharmacology |
ATC code
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D08AJ06 (WHO) |
Hazards |
Main hazards |
corrosive [2] |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Y verify (what is YN ?) |
Infobox references |
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Didecyldimethylammonium chloride (DDAC) is an antiseptic/disinfectant that is used in many biocidal applications. They cause disruption of intermolecular interactions and dissociation of lipid bilayers. They are broad spectrum bactericidal and fungicidal and can be used as disinfectant cleaner for linen, recommended for use in hospitals, hotels and industries. It is also used in gynaecology, surgery, ophthalmology, pediatrics, OT, and for the sterilization of surgical instruments, endoscopes and surface disinfection.
In mice this disinfectant was found to cause infertility and birth defects.[3]
See also
- Dimethyldioctadecylammonium chloride - longer di-C18 analogue
References
- ^ a b c d e f g "Didecyl dimethyl ammonium chloride", Household Products Database, US Department of Health and Human Services, 2016
- ^ a b c Record of didecyldimethylammonium chloride in the GESTIS Substance Database of the Institute for Occupational Safety and Health, accessed on 2 November 2007
- ^ Brendan Maher (2008). "Lab disinfectant harms mouse fertility". Nature. 453 (7198): 964. PMID 18563110. doi:10.1038/453964a.
Antiseptics and disinfectants (D08)
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Acridine derivatives |
- Ethacridine lactate
- 9-Aminoacridine
- Euflavine
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Biguanides and amidines |
- Dibrompropamidine
- Chlorhexidine#
- Propamidine
- Hexamidine
- Polihexanide
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Phenol and derivatives |
- Hexachlorophene
- Policresulen
- Phenol
- Triclosan
- Triclocarban
- Chloroxylenol#
- Biphenylol
- Fenticlor
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Nitrofuran derivatives |
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Iodine products |
- Iodine/octylphenoxypolyglycolether
- Povidone-iodine#
- Diiodohydroxypropane
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Quinoline derivatives |
- Dequalinium
- Chlorquinaldol
- Oxyquinoline
- Clioquinol
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Quaternary ammonium compounds |
- Benzalkonium
- Benzethonium chloride
- Cetrimonium (bromide/chloride)
- Cetylpyridinium
- Cetrimide
- Benzoxonium chloride
- Didecyldimethylammonium chloride
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Mercurial products |
- Mercuric amidochloride
- Phenylmercuric borate
- Mercuric chloride
- Merbromin
- Thiomersal
- Mercuric iodide
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Silver compounds |
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Alcohols |
- Propanol (propyl alcohol)
- Isopropanol (isopropyl alcohol)
- Ethanol (ethyl alcohol)#
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Other |
- Potassium permanganate
- Sodium hypochlorite
- Hydrogen peroxide
- Eosin
- Tosylchloramide
- Octenidine dihydrochloride
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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UpToDate Contents
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English Journal
- Effect of modified montmorillonites on the biodegradation and adsorption of biomarkers such as hopanes, steranes and diasteranes.
- Ugochukwu UC, Head IM, Manning DA.SourceSchool of Civil Engineering and Geosciences, University of Newcastle Upon Tyne, Newcastle Upon Tyne, NE1 7RU, UK, ugouzochukwu@yahoo.com.
- Environmental science and pollution research international.Environ Sci Pollut Res Int.2013 Jun 8. [Epub ahead of print]
- The effect of modified montmorillonites on the biodegradation and adsorption of selected steranes, diasteranes and hopanes was investigated in aqueous clay/oil microcosm experiments with a hydrocarbon degrading microorganism community. The unmodified montmorillonite was treated with didecyldimethyla
- PMID 23749373
- Effect of chemical permeation enhancers on stratum corneum barrier lipid organizational structure and interferon alpha permeability.
- Moghadam SH, Saliaj E, Wettig SD, Dong C, Ivanova MV, Huzil JT, Foldvari M.SourceSchool of Pharmacy, University of Waterloo, 200 University Avenue West, Waterloo, ON, Canada, N2L 3G1.
- Molecular pharmaceutics.Mol Pharm.2013 Jun 3;10(6):2248-60. doi: 10.1021/mp300441c. Epub 2013 May 2.
- The outermost layer of the skin, known as the stratum corneum (SC), is composed of dead corneocytes embedded in an intercellular lipid matrix consisting of ceramides, free fatty acids, and cholesterol. The high level of organization within this matrix protects the body by limiting the permeation of
- PMID 23587061
- Combined treatments of enterocin AS-48 with biocides to improve the inactivation of methicillin-sensitive and methicillin-resistant Staphylococcus aureus planktonic and sessile cells.
- Caballero Gómez N, Abriouel H, Grande MJ, Pérez Pulido R, Gálvez A.SourceÁrea de Microbiología, Departamento de Ciencias de la Salud, Facultad de Ciencias Experimentales, Universidad de Jaén, 23071 Jaén, Spain.
- International journal of food microbiology.Int J Food Microbiol.2013 May 15;163(2-3):96-100. doi: 10.1016/j.ijfoodmicro.2013.02.018. Epub 2013 Mar 5.
- Control of staphylococci during cleaning and disinfection is important to the food industry. Broad-spectrum bacteriocins with proved anti-staphylococcal activity, such as enterocin AS-48, could open new possibilities for disinfection in combination with biocides. In the present study, enterocin AS-4
- PMID 23558192
Japanese Journal
- Acute pulmonary toxicity and inflammation induced by combined exposure to didecyldimethylammonium chloride and ethylene glycol in rats
- 低温及び有機物存在下における石灰水を使用した逆性石鹸系消毒薬の鳥インフルエンザウイルス及び牛エンテロウイルスに対する消毒効果
- 日本獣医師会雑誌 = Journal of the Japan Veterinary Medical Association 66(9), 633-637, 2013-09-20
- NAID 10031195047
- Biofilm-Forming Activity of Bacteria Isolated from Toliet Bowl Biofilms and the Bactericidal Activity of Disinfectants against The lsolates
Related Links
- Detailed Toxicity Information This Chemical Parent Chemical Acute Toxicity 2 Didecyl dimethyl ammonium chloride Dialkyl (85%C18, 15%C16) dimethyl ammonium chloride WHO Acute Hazard TRI Acute Hazard Material Safety ...
- Didecyl dimethyl ammonium chloride | C22H48ClN | CID 23558 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists ... ...
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