A novel model of pain sensation using superfused gastrosplenic omentum preparation of anesthetized rats.
Yang SJ1, Katori M, Majima M.
Journal of pharmacological sciences.J Pharmacol Sci.2008 Feb;106(2):249-56. Epub 2008 Feb 9.
A pain model for screening analgesics was established in anesthetized rats. The omenta of urethane-anesthetized rats were exteriorized, fixed in a plastic chamber, and superfused with Tyrode solution. Administration of bradykinin (BK) in the chamber elicited the reflex hypertensive response (RHR). M
Expression of alpha 4 and alpha 7 nicotinic receptors in the brainstem of female rabbits after coitus.
Centeno ML1, Luo J, Lindstrom JM, Caba M, Pau KY.
Brain research.Brain Res.2004 Jun 25;1012(1-2):1-12.
Coital signaling in the female rabbit involves sequential events in the brainstem and hypothalamus, resulting in a massive release of hypothalamic gonadotropin-releasing hormone (GnRH) that peaks within 1-2 h after mating. The neural connections between coitus and GnRH release involves norepinephrin
Histamine H1 receptor antagonism by cetirizine in isolated guinea pig tissues: influence of receptor reserve and dissociation kinetics.
Christophe B1, Carlier B, Gillard M, Chatelain P, Peck M, Massingham R.
European journal of pharmacology.Eur J Pharmacol.2003 May 30;470(1-2):87-94.
We characterised histamine H(1) receptor antagonism by cetirizine and its enantiomers on isolated guinea pig ileum and trachea. Competitive or mixed (competitive and apparent noncompetitive) antagonism profiles were observed. The order of potency was: chlorpheniramine> or =mepyramine>levocetir
THE adrenolytic drug dibenamine hydrochloride (dibenzyl-beta-chlorethyl amine hydrochloride) is presented as a diagnostic aid when the presence of a pheochromocytoma is suspected and as a therapeutic agent once the diagnosis ...
DIBENAMINE | C16H18ClN | CID 5820 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. ... National ...