English Journal
- Anticancer activity and mechanisms of diacetyldianhydrogalactitol on hepatoma QGY-7703 cells.
- Zhang XY, Lian Yan X, Guo W, Xu B, Li M, Zhou Y, Rong Cui J.SourceState Key Laboratory of Natural and Biomimetic Drugs, Peking University Health Science Center, Beijing, China.
- Anti-cancer drugs.Anticancer Drugs.2009 Nov;20(10):926-31. doi: 10.1097/CAD.0b013e328330c7b9.
- Diacetyldianhydrogalactitol (DADAG) is a member of the hexitols which shows a significant anticancer effect. Despite the fact that the antitumor effects of DADAG have been studied in a number of cell lines, the mechanism of its action remains unclear. Herein, we explored antitumor effects of DADAG a
- PMID 19741503
- Complete remissions in chemotherapy of lung cancer models induced in mice by asbestos.
- Smith WE, Hubert DD, Yazdi E, Holiat SM, Bissell EC, Watts LM, Baylouny RA, Sobel HJ.SourceHealth Research Institute, Fairleigh Dickinson University, Madison, NJ, USA.
- The Mount Sinai journal of medicine, New York.Mt Sinai J Med.2005 Jan;72(1):23-32.
- Chemotherapy trials were run with mice bearing transplants of carcinomas originally induced from fetal mouse lung cells by asbestos. After treatments with a nitrosourea (PCNU), mice bearing transplants of a large-cell carcinoma (ASB XIV) had complete remissions (CR) in 13 of 20 animals on a 15 mg/kg
- PMID 15682259
- [Apoptosis of hepatocarcinoma cell line HLE induced by the combination of wild type P53 gene and 1,2:5,6-dianhydro-3,4-diacetylgalactitol].
- Lai XJ, Cao LZ, Zhou Y, Lan XW, Liao ZH, Zhou SF.SourceDepartment of Biochemistry, Guangxi Medical University, Nanning, Guangxi, 530021, P.R.China. laixiangjin@sina.com
- Ai zheng = Aizheng = Chinese journal of cancer.Ai Zheng.2004 Oct;23(10):1139-43.
- BACKGROUND & OBJECTIVE: P53 gene is a tumor suppressor gene,and its mutation in human tumor cells is frequently observed. Previous studies revealed that wild type p53 (wt-p53)gene can suppress proliferation ,and induce apoptosis of tumor cells. However,the enhancive effect of wt-p53 on apoptosis
- PMID 15473923
Related Links
- Dianhydrogalactitol (Science: chemical) 1,2:5,6-dianhydrodulcitol. One of the cytotoxic dihalohexitols that may have alkylating antineoplastic activity. It causes bone marrow toxicity. The active form is thought to be the diepoxide. ...
- Dianhydrogalactitol information including symptoms, causes, diseases, symptoms, treatments, and other medical and health issues. ... Introduction: Dianhydrogalactitol Description of Dianhydrogalactitol Dianhydrogalactitol: One of ...
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