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- 1. 高グレードの神経膠腫に対する実験的治療アプローチ experimental treatment approaches for high grade gliomas
- 2. セザリー症候群の治療 treatment of sezary syndrome
- 3. βサラセミアの治療 treatment of beta thalassemia
- 4. 標準療法に対し難治性の甲状腺分化癌：化学療法 differentiated thyroid cancer refractory to standard treatment chemotherapy
- 5. アントラサイクリン系以外の癌化学療法剤の心毒性 cardiotoxicity of nonanthracycline cancer chemotherapy agents
English Journal
- Chimeric antibodies.
- Kurosawa K, Lin W, Ohta K.SourceDepartment of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, Tokyo, Japan.
- Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2014;1060:139-48. doi: 10.1007/978-1-62703-586-6_8.
- Here we describe a detailed protocol for the one-step preparation of antigen-specific human chimeric immunoglobulin G (IgG) monoclonal antibodies (mAbs) using an in vitro antibody design method referred to as the ADLib (Autonomously Diversifying Library) system. This method employs a chicken B cell
- PMID 24037840
- Current status of healthy human skin models: can histone deacetylase inhibitors potentially improve the present replacement models?
- Lemper M, Snykers S, Vanhaecke T, De Paepe K, Rogiers V.SourceDepartment of Toxicology, Center for Pharmaceutical Research, Vrije Universiteit Brussel, Belgium.
- Skin pharmacology and physiology.Skin Pharmacol Physiol.2014;27(1):36-46. doi: 10.1159/000351363. Epub 2013 Aug 6.
- Histone deacetylase inhibitors (HDACi), a relatively new group of epigenetic agents, are being investigated as powerful chemotherapeutics because of their antiproliferative and prodifferentiation effects both in vitro and in vivo, in various tumor cell lines. Only little is known with respect to the
- PMID 23941820
- Regulation of the MIR155 host gene in physiological and pathological processes.
- Elton TS, Selemon H, Elton SM, Parinandi NL.SourceDavis Heart and Lung Research Institute, The Ohio State University, Columbus, OH, USA; College of Pharmacy, Division of Pharmacology, The Ohio State University, Columbus, OH, USA; Department of Medicine, Division of Cardiology, The Ohio State University, Columbus, OH, USA. Electronic address: terry.elton@osumc.edu.
- Gene.Gene.2013 Dec 10;532(1):1-12. doi: 10.1016/j.gene.2012.12.009. Epub 2012 Dec 14.
- MicroRNAs (miRNAs), a family of small nonprotein-coding RNAs, play a critical role in posttranscriptional gene regulation by acting as adaptors for the miRNA-induced silencing complex to inhibit gene expression by targeting mRNAs for translational repression and/or cleavage. miR-155-5p and miR-155-3
- PMID 23246696
Japanese Journal
- 概日リズムと代謝のクロストークにおけるNAMPT/NAD合成系およびNAD依存性脱アセチル化酵素SIRT1の重要性 (特集 概日リズムと疾患 : 病態・診断・治療の最新知見) -- (特論)
- 吉野 純
- 日本臨床 71(12), 2187-2193, 2013-12
- NAID 40019874742
- Requirement of Retinoic Acid Receptor β for Genipin Derivative-Induced Optic Nerve Regeneration in Adult Rat Retina
- Koriyama Yoshiki,Takagi Yusuke,Chiba Kenzo,Yamazaki Matsumi,Sugitani Kayo,Arai Kunizo,Suzuki Hirokazu,Kato Satoru
- PLoS ONE 8(8), e71252, 2013-08-06
- … Neuritogenic activity was mediated by S-nitrosylation of histone deacetylase-2 (HDAC2), which subsequently induced retinoic acid receptor β (RARβ) expression via chromatin remodeling in vitro. …
- NAID 120005327241
- 多発性骨髄腫における薬剤耐性とその克服
- 菊池 次郎,古川 雄祐
- 血液内科 67(1), 112-122, 2013-07
- NAID 40019782888
Related Links
- ヒストン脱アセチル化酵素(Histone Deacetylase)はヌクレオソーム構造を変化させることにより、様々な遺伝子の発現を調節する重要な働きをしていると考えられています。また、細胞周期の進行、分化に関与しており、この調節が ...
- Deacetylase Assay Kit ＜特徴＞ ・操作が簡便で、安定性、再現性が優れています。高感度で測定可能です。 ・B/F 分離を必要としないホモジーニアスなアッセイ系です。 ・大規模なドラッグスクリーニングにも最適です。 ・放射能 ...
Related Pictures
★リンクテーブル★
| リンク元 | 「デアセチラーゼ」「脱アセチル酵素」「脱アセチル化酵素」 |
| 拡張検索 | 「histone deacetylase inhibitor」 |
「デアセチラーゼ」
「脱アセチル酵素」
「脱アセチル化酵素」
「histone deacetylase inhibitor」
ヒストン脱アセチル化酵素阻害薬、ヒストン脱アセチル化酵素阻害剤、ヒストンデアセチラーゼ阻害薬、ヒストンデアセチラーゼ阻害剤
- 関
- HDACI