Murine mast cells secrete and respond to interleukin-33.
Tung HY1, Plunkett B, Huang SK, Zhou Y.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.J Interferon Cytokine Res.2014 Mar;34(3):141-7. doi: 10.1089/jir.2012.0066. Epub 2013 Sep 12.
Interleukin-33 (IL-33) appears to play a crucial role in the expression of allergic diseases, but its cellular source and regulatory mechanisms remain to be fully elucidated. Mast cells, one of the major effecter cell populations in mediating allergy, express high levels of IL-33 receptor, ST2, and
T-cell regulation by CD52-expressing CD4 T cells appears to operate by two different and possibly synergistic mechanisms. The first is by its release from the cell surface of CD4 T cells that express high levels of CD52 that then binds to the inhibitory sialic acid-binding immunoglobulin-like lectin
Effect of chondroitin sulphate C on the in vitro and in vivo chondrogenesis of mesenchymal stem cells in crosslinked type II collagen scaffolds.
Chen WC1, Wei YH, Chu IM, Yao CL.
Journal of tissue engineering and regenerative medicine.J Tissue Eng Regen Med.2013 Aug;7(8):665-72. doi: 10.1002/term.1463. Epub 2012 Mar 12.
This study evaluates the crosslinkage effect of chondroitin sulphate C (CSC) and type II collagen (COL II) on chondrogenesis of mesenchymal stem cells (MSCs) in vitro and in vivo. In the in vitro studies, our results show that the weight ratio CSC:COL II that reaches 1.2:100 (CSC1.2/100 -COL II scaf