- a small opening or crevice (especially in a rock face or wall)
- something remote; "he explored every nook and cranny of science" (同)nooks and crannies
- a capacity unit used for measuring fresh herring
- Harvey with a modern twist: How and why conducting arteries amplify the pressure wave originating from the heart.
- Schaafsma A.Author information Martini Ziekenhuis Groningen, v. Swietenplein 1, 9728 NT Groningen, The Netherlands. Electronic address: A.Schaafsma@mzh.nl.AbstractCurrent views on cardiovascular physiology differ little from that published by William Harvey in 1628: the heart delivers all energy for blood circulation, forcing its contents into the aorta, via arteries, arterioles and capillaries into the venous system that collects the blood and returns it to the right side of the heart. Similarly, blood from the right side passes through pulmonary arteries and arterioles to pulmonary veins before returning to the left side of the heart. However, from aorta to capillaries there is a great increase in overall cross-sectional area. The arterial system can be seen as a funnel, the heart pumping blood into its narrow end. Theoretically, this implies that pulsatile energy delivered by the heart dilutes significantly along its way through the arterial tree. Also, unfavorable tissue conditions, such as elevated pressure, impede proper perfusion when blood can pass just as easy through adjacent capillary systems. Finally, blood will experience more resistance to flow for capillary systems more distant to the heart due to its longer trajectory. This implies that capillary systems closer to the heart are more easily perfused than more distant ones. In reality, the pulse from the heart has been shown to increase and accelerate towards periphery. This, together with transcranial Doppler observations on the variation in wave morphology in intracranial arteries, for instance during CO2-reactivity testing and during cardiac arrhythmia, has led to the theory of arterial acceleration: at stroke onset, the arterial pressure wave resulting from myocardial contraction is enhanced by a short-lasting and well-synchronised contraction within the smooth muscle layers of conducting arteries. This results in a temporary 'stiffening' of the arterial tree by which cardiac pressure during early systole is amplified and distributed into all the body's capillary systems. This theory would overcome all theoretical and observational concerns sketched above. Such arterial acceleration limited to the first 100-150ms of every heart beat would augment, accelerate and distribute the pulse generated by heart contraction over the full length and branching of the arterial tree, thereby enforcing a widespread tissue perfusion. It is obvious that the theory of arterial acceleration is a major shift of paradigm forcing us to reconsider many aspects of cardiovascular physiology. Moreover, it improves our understanding how blood expelled by the heart through the small lumen of the aortic notch has sufficient energy to reach every nook and cranny of our body.
- Medical hypotheses.Med Hypotheses.2014 May;82(5):589-94. doi: 10.1016/j.mehy.2014.02.016. Epub 2014 Feb 24.
- Current views on cardiovascular physiology differ little from that published by William Harvey in 1628: the heart delivers all energy for blood circulation, forcing its contents into the aorta, via arteries, arterioles and capillaries into the venous system that collects the blood and returns it to
- PMID 24613738
- A novel pressure difference-induced perforation aortic stent-grafts system: an experimental study.
- Deng GY1, Zhou J, Lu QS, Wang L, Hou LW, Dong J, Wang JN, Zhang SM, Zhao ZQ, Jing ZP.Author information 1Department of Vascular Surgery, Changhai Hospital, Second Military Medical University, Shanghai 200433, China.AbstractBACKGROUND: Most of endovascular stent-graft modifications to preserve side branch must be customized according to extensive pre-operative assessment, which may not be possible in many hospitals and emergency settings. The study was to develop a novel stent-grafts system that would allow in situ "fenestration", with less reliance on preoperative imaging.
- Chinese medical journal.Chin Med J (Engl).2013 Apr;126(7):1264-8.
- BACKGROUND: Most of endovascular stent-graft modifications to preserve side branch must be customized according to extensive pre-operative assessment, which may not be possible in many hospitals and emergency settings. The study was to develop a novel stent-grafts system that would allow in situ "fe
- PMID 23557556
- [Initial study and evaluation on alveolar bone graft by palate side approach].
- Yang C1, Shi B, Liu K, Zheng Q.Author information 1Dept. of Cleft Lip and Palate, West China School of Stomatology, Sichuan University, Chengdu 610041, China.AbstractOBJECTIVE: To observe and improve the short-term outcome of alveolar bone graft (ABG) by palate side approach.
- Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology.Hua Xi Kou Qiang Yi Xue Za Zhi.2013 Feb;31(1):30-3.
- OBJECTIVE: To observe and improve the short-term outcome of alveolar bone graft (ABG) by palate side approach.METHODS: ABG by palate side approach was performed in twenty patients with non-syndromic unilateral complete cleft lip and palate. Eight patients were incomplete cleft alveolar, and twelve p
- PMID 23484297
- Pathology, diagnosis, and classification of pressure ulcers : comparing clinical and imaging techniques
- NIXON JANE,CRANNY GILLIAN,BOND SENGA
- Wound repair and regeneration 13(4), 365-372, 2005-07-01
- NAID 10018026636
- 柴崎 文一
- 情報処理学会研究報告. 人文科学とコンピュータ研究会報告 2001(96), 41-48, 2001-10-12
- … Once the internet establishes itself in society, it develops on its own on the basis of this property and infiltrates every nook and cranny of society. …
- NAID 110002930143
- 30 Aug 2011 ... See cranny defined for English-language learners ». See cranny defined for kids ». Examples of CRANNY. We saw strange, colorful creatures in the crannies of the reef while scuba diving. We explored every cranny of the old ...