コポリマー1
- 関
- glatiramer acetate
WordNet
- a polymer consisting of two or more different monomers
PrepTutorEJDIC
- 共重合体(2種類以上の単量体の重合による高分子化合物)
UpToDate Contents
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English Journal
- Synthesis of β-cyclodextrin containing copolymer via "click" chemistry and its self-assembly in the presence of guest compounds.
- Zhang J, Ellsworth K, Ma PX.SourceDepartment of Biologic and Materials Sciences, University of Michigan, Ann Arbor, MI 48109, USA.
- Macromolecular rapid communications.Macromol Rapid Commun.2012 Apr 23;33(8):664-71. doi: 10.1002/marc.201100814. Epub 2012 Feb 9.
- We report the synthesis of a hydrophilic copolymer with one polyethylene glycol (PEG) block and one β-cyclodextrin (β-CD) containing block by a "click" reaction between azido-substituted β-CD and propargyl flanking copolymer. (1)H NMR study suggested a highly efficient conjugation of β-CD units
- PMID 22318939
- Novel biomimetic vectors with endosomal-escape agent enhancing gene transfection efficiency.
- Sun X, Liu C, Liu D, Li P, Zhang N.SourceThe School of Pharmaceutical Science, Shandong University, 44 Wenhua Xi Road, Ji'nan, Shandong Province 250012, China.
- International journal of pharmaceutics.Int J Pharm.2012 Apr 4;425(1-2):62-72. Epub 2012 Jan 14.
- Low cytotoxicity and high transfection efficiency are critical issues in designing current non-viral gene delivery vectors. In the present study, a novel biomimetic lipid-polycation copolymer, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-graft-poly(l-lysine)-block-poly(ethylene glycol) (DOPE-g-PLL-
- PMID 22266532
Japanese Journal
- Oral tolerance to copolymer 1 in myelin basic protein (MBP) TCR transgenic mice : cross-reactivity with MBP-specific TCR and differential induction of anti-inflammatory cytokines
- MARON Ruth,SLAVIN Anthony J.,HOFFMANN Ethan,KOMAGATA Yoshinori,WEINER Howard L.
- International immunology 14(2), 131-138, 2002-02-01
- NAID 10010591736
Related Links
- 臨床試験情報 多発性硬化症(RRMS) 疾患: 再発寛解型MS 薬剤: Copolymer 1:4つのアミノ酸から成る化学合成ポリペプチドの酢酸塩 抗炎症作用、神経保護作用及び神経組織修復作用を有する 海外使用経験: 52ヵ国で承認 ...
- glatiramer acetate Copaxone Pharmacologic class: Immunomodulator Therapeutic class: Multiple sclerosis agent Pregnancy risk category B Action Unknown. Thought to alter ... If approved, copolymer 1 would be the third drug in 3 ...
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- copolymer-1
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- 酢酸グラチラマー
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- co-polymer