WordNet

PrepTutorEJDIC

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

FasL-triggered death of Jurkat cells requires caspase 8-induced, ATP-dependent cross-talk between Fas and the purinergic receptor P2X(7).

Aguirre A, Shoji KF, Sáez JC, Henríquez M, Quest AF.SourceFacultad de Medicina, Centro de Estudios Moleculares de la Célula, Universidad de Chile, Santiago, Chile.
Journal of cellular physiology.J Cell Physiol.2013 Feb;228(2):485-93. doi: 10.1002/jcp.24159.
Fas ligation via the ligand FasL activates the caspase-8/caspase-3-dependent extrinsic death pathway. In so-called type II cells, an additional mechanism involving tBid-mediated caspase-9 activation is required to efficiently trigger cell death. Other pathways linking FasL-Fas interaction to activat
PMID 22806078

Rho guanine nucleotide exchange factor is an NFL mRNA destabilizing factor that forms cytoplasmic inclusions in amyotrophic lateral sclerosis.

Droppelmann CA, Keller BA, Campos-Melo D, Volkening K, Strong MJ.SourceMolecular Brain Research Group, Robarts Research Institute, University of Western Ontario, London, Ontario, Canada.
Neurobiology of aging.Neurobiol Aging.2013 Jan;34(1):248-62. doi: 10.1016/j.neurobiolaging.2012.06.021. Epub 2012 Jul 24.
Amyotrophic lateral sclerosis (ALS) is an adult-onset progressive disorder of unknown etiology characterized by the selective degeneration of motor neurons. Recent evidence supports the hypothesis that alterations in RNA metabolism in motor neurons can explain the development of protein inclusions,
PMID 22835604