collision-induced dissociation

衝突解離

関

CID

WordNet

1. reason or establish by induction
2. cause to arise; "induce a crisis" (同)bring_on
3. produce electric current by electrostatic or magnetic processes (同)induct
4. cause to do; cause to act in a specified manner; "The ads induced me to buy a VCR"; "My children finally got me to buy a computer"; "My wife made me buy a new sofa" (同)stimulate, cause, have, get, make
5. cause to occur rapidly; "the infection precipitated a high fever and allergic reactions" (同)stimulate, rush, hasten
6. (physics) a brief event in which two or more bodies come together; "the collision of the particles resulted in an exchange of energy and a change of direction" (同)hit
7. a conflict of opposed ideas or attitudes or goals; "a collision of interests"
8. an accident resulting from violent impact of a moving object; "three passengers were killed in the collision"; "the collision of the two ships resulted in a serious oil spill"
9. a state in which some integrated part of a persons life becomes separated from the rest of the personality and functions independently (同)disassociation
10. (chemistry) the temporary or reversible process in which a molecule or ion is broken down into smaller molecules or ions
11. the act of removing from association
12. brought about or caused; not spontaneous; "a case of steroid-induced weakness"

PrepTutorEJDIC

1. Criminal investigation Department [of Scotland Yard]ロンドン警視庁捜査課
2. 〈人〉‘に'『勧めて』(…)『させる』 / …‘を'『引き起こす』,もたらす(cause) / 〈電気〉‘を'誘導する / …‘を'帰納する
3. (列車などの…との)『衝突』《+『of』+『名』+『with』+『名』》 / (意見・利害などの…との)衝突,不調和《+『of』+『名』+『with』+『名』》
4. 分離[作用];解離

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/03/20 08:54:42」(JST)

wiki en

[Wiki en表示]

In mass spectrometry, collision-induced dissociation (CID), referred to by some as collisionally activated dissociation (CAD), is a mechanism by which to fragment molecular ions in the gas phase. The molecular ions are usually accelerated by some electrical potential to high kinetic energy and then allowed to collide with neutral molecules (often helium, nitrogen or argon). In the collision some of the kinetic energy is converted into internal energy which results in bond breakage and the fragmentation of the molecular ion into smaller fragments. These fragment ions can then be analyzed by a mass spectrometer.

CID and the fragment ions produced by CID are used for several purposes. Partial or complete structural determination can be achieved. In some cases identity can be established based on previous knowledge without determining structure. Another use is in simply achieving more sensitive and specific detection. By looking for a unique fragment ion you can detect a given molecule in the presence of other molecules of the same nominal molecular weight, essentially reducing the background and increasing the limit of detection.

Examples

In a triple quadrupole mass spectrometer there are three quadrupoles. The first quadrupole termed "Q1" can act as a mass filter and transmits a selected ion and accelerates it towards "Q2" which is termed a collision cell. The pressure in Q2 is higher and the ions collides with neutral gas in the collision cell and fragments by CID. The fragments are then accelerated out of the collsion cell and enter Q3 which scans through the mass range, analyzing the resulting fragments (as they hit a detector). This produces a mass spectrum of the CID fragments from which structural information or identity can be gained. Many other experiments using CID on a triple quadrupole exist such as precursor ion scans that determines where a specific fragment came from rather than what fragments are produced by a given molecule.

SORI-CID (sustained off-resonance irradiation collision-induced dissociation) is a CID technique used in Fourier Transform Ion Cyclotron Resonance mass spectrometry which involves accelerating the ions in cyclotron motion (in a circle inside of an ion trap) and then increasing the pressure resulting collisions that produce CID fragments.

See also

• Higher-energy collisional_dissociation (HCD)
• electron-transfer dissociation (ETD)
• electron-capture dissociation (ECD)
• infrared multiphoton dissociation (IRMPD)

References

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

• 1. 解離性健忘：疫学、病因、臨床症状、経過、および診断 dissociative amnesia epidemiology pathogenesis clinical manifestations course and diagnosis
• 2. 心的外傷後ストレス障害の解離性：疫学、臨床症状、評価、および診断 dissociative aspects of posttraumatic stress disorder epidemiology clinical manifestations assessment and diagnosis
• 3. 解離性同一性障害：疫学、病因、臨床症状、経過、評価、および診断 dissociative identity disorder epidemiology pathogenesis clinical manifestations course assessment and diagnosis
• 4. Depersonalization/derealization disorder: Epidemiology, pathogenesis, clinical manifestations, course, and diagnosis
• 5. QRS幅の広い頻脈の診断のアプローチ approach to the diagnosis of wide qrs complex tachycardias

English Journal

• HRMS studies on the fragmentation pathways of metallapentalyne.

• Lin Z1, Zhu C1, Xia H1.
• Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.Spectrochim Acta A Mol Biomol Spectrosc.2015 Feb 5;136 Pt B:906-10. doi: 10.1016/j.saa.2014.09.112. Epub 2014 Oct 5.
• The electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry (ESI FT-ICR MS) using collision-induced dissociation (CID) method was applied to investigate the characteristic fragment ions of metalla-aromatic complexes for the first time. The fragmentation process of osmapen
• PMID 25459615

• Identification of major α-glucosidase inhibitors in Radix Astragali and its human microsomal metabolites using ultrafiltration HPLC-DAD-MS(n.).

• Zhao H1, Zhang Y1, Guo Y2, Shi S3.
• Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.2015 Feb;104:31-7. doi: 10.1016/j.jpba.2014.09.029. Epub 2014 Sep 30.
• Radix Astragali is one of the most popular traditional medicinal herbs with α-glucosidase inhibitory activity, however, more comprehensive information regarding α-glucosidase inhibition of Radix Astragali and its metabolites is yet unknown. Here, an ultrafiltration HPLC-DAD-MS(n) was developed to
• PMID 25474715

• Novel 2-alkyl-1-ethylpyridinium ionic liquids: synthesis, dissociation energies and volatility.

• Vilas M1, Rocha MA, Fernandes AM, Tojo E, Santos LM.
• Physical chemistry chemical physics : PCCP.Phys Chem Chem Phys.2015 Jan 28;17(4):2560-72. doi: 10.1039/c4cp05191b. Epub 2014 Dec 10.
• This work presents the synthesis, volatility study and electrospray ionization mass spectrometry with energy-variable collision induced dissociation of the isolated [(cation)2(anion)](+) of a novel series of 2-alkyl-1-ethyl pyridinium based ionic liquids, [(2)CN-2(1)C2Py][NTf2]. Compared to the imid
• PMID 25493639

Japanese Journal

• Collision-Induced Dissociation Study of the Adduct Ions Produced in NO₃⁻-Free Area of Atmospheric Pressure Negative Corona Discharges under Ambient Air Conditions (Mass Spectrometry)

• Sekimoto Kanako,Matsuda Natsuki,Takayama Mitsuo
• Journal of the Mass Spectrometry Society of Japan = 質量分析 61(3), 1-5, 2013-06
• NAID 40019754386

• 移動度分析法によって分離された気相クラスター異性体イオンの分光と反応 (特集 移動度分析法の進展とその応用)

• 美齊津 文典,小安 喜一郎
• エアロゾル研究 28(2), 113-118, 2013
• NAID 40019745717

• Thermochemistry of Non-Covalent Ion–Molecule Interactions

• Armentrout P. B.,Rodgers M. T.
• Mass Spectrometry 2(Special_Issue), S0005-S0005, 2013
• … The thermochemistry of non-covalent ion–molecule complexes has been examined by measuring quantitative bond dissociation energies using threshold collision-induced dissociation in guided ion beam tandem mass spectrometers (GIBMS). …
• NAID 130003380173

Related Links

• Collision‐Induced Dissociation (CID) of Peptides and Proteins

Fast methods are those in which the input of energy occurs rapidly relative to unimolecular dissociation, such as single‐collision CID at kiloelectron volts or electron volts (in the laboratory frame of reference) kinetic energy. Slow CID ...

• How does it really work and what it can (or can't) tell you

Collision-induced dissociation: How does it really work and what it can (or can't) tell you Peter B. Armentrout Department of Chemistry, University of Utah, Salt ... What is CID? From IUPAC Compendium on Analytical Nomenclature ...

Related Pictures

---

★リンクテーブル★

リンク元	「CID」「衝突解離」
関連記事	「induce」「dissociation」「induced」「collision」

「CID」

　　[★]

• 衝突解離 collision-induced dissociation
• combined immunodeficiency
• 巨細胞封入体症 cytomegalic inclusion disease

　

「衝突解離」

　　[★]

英

collision-induced dissociation、CID

「induce」

　　[★]

• v.

• 誘発する、誘導する、誘起する、導入する、引き起こす

関

cause、challenge、derivation、elicit、elicitation、evocation、evoke、guidance、induction、inductive、introduce、introduction、precipitate、provocation、provoke、spark

　 　 　 　 　 　

「dissociation」

　　[★]

• n.

• 解離

関

detachment、dissection、dissociate、dissociative disorder、dissociative reaction、fugue、maceration、unbinding

　 　 　 　

「induced」

　　[★]

• v.

• (induceの過去分詞)誘導される、引き起こされる

hypercalcaemia induced pancreatitis 高カルシウム血症による膵炎

　

「collision」

　　[★]

• n.

• 衝突

関

collide、collisional、crash、impinge、impingement