WordNet

a horizontal plant stem with shoots above and roots below serving as a reproductive structure (同)rootstock, rootstalk

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1. ハーブ剤および栄養補助食品による肝毒性 hepatotoxicity due to herbal medications and dietary supplements

Anti-hypertensive effects of shichimotsukokato in 5/6 nephrectomized Wistar rats mediated by the DDAH-ADMA-NO pathway.

Bai F1, Makino T, Ono T, Mizukami H.
Journal of natural medicines.J Nat Med.2012 Oct;66(4):583-90. doi: 10.1007/s11418-011-0625-8. Epub 2012 Feb 21.
Shichimotsukokato (SKT) is a Kampo formula, comprising astragalus root, phellodendron bark, rehmannia root, peony root, cnidium rhizome, Japanese angelica root, and uncaria hook. It is prescribed to hypertensive patients who complain of a sensation of a rush of blood to the head, shoulder stiffness,
PMID 22350214

Components of rhizome extract of Cnidium officinale Makino and their in vitro biological effects.

Bae KE1, Choi YW, Kim ST, Kim YK.
Molecules (Basel, Switzerland).Molecules.2011 Oct 21;16(10):8833-47. doi: 10.3390/molecules16108833.
The anti-inflammatory and anticancer activities of a methanol extract of the rhizome of Cnidium officinale were investigated. Four compounds, namely falcarindiol (1), 6-hydroxy-7-methoxy-dihydroligustilide (2), ligustilidiol (3), and senkyunolide H (4) were isolated from the extract of the rhizome o
PMID 22019572

A modified formulation of Chinese traditional medicine improves memory impairment and reduces Aβ level in the Tg-APPswe/PS1dE9 mouse model of Alzheimer's disease.

Jeon S1, Bose S, Hur J, Jun K, Kim YK, Cho KS, Koo BS.
Journal of ethnopharmacology.J Ethnopharmacol.2011 Sep 1;137(1):783-9. doi: 10.1016/j.jep.2011.06.046. Epub 2011 Jul 5.
ETHNOPHARMACOLOGICAL RELEVANCE: SuHeXiang Wan (SHXW), a Chinese traditional medicine has been used orally for the treatment of seizures, infantile convulsion, stroke and so forth. Previously, we reported the effects of modified SHXW essential oil mixture of the fragrance containing herbs on the seda
PMID 21762767

Assessment of the Antimutagenic Effects of Aqueous Extracts from Herbal Medicines against N-Alkyl-N-nitrosoureas-induced Mutagenicity Using the umu Test

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Genes and Environment 36(2), 33-38, 2014
… Astragalus Root, Bupleurum Root, Cimicifuga Rhizome, Cnidium Rhizome, Glycyrrhiza, Paony Root, Polygonatum Rhizome, Poria Sclerotium, and Processed Ginger, moderately inhibited N-alkyl-N-nitrosoureas-induced mutagenicity (IC50>7.0 mg/mL), and eight aqueous extracts; …
NAID 130004943658

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Biological & pharmaceutical bulletin 25(4), 523-525, 2002-04-01
… It contains 6 herbs: peony root, cnidium rhizome, safflower, cyperus rhizome, saussurea root (JP XIV), and Salvia miltiorrhiza root. …
NAID 110003638815

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