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1. シスプラチン腎障害 cisplatin nephrotoxicity
2. 化学療法関連腎毒性および腎不全患者における用量調整 chemotherapy related nephrotoxicity and dose modification in patients with renal insufficiency
3. 成人における抗癌剤の投与 dosing of anticancer agents in adults
4. 悪性腫瘍関連腎疾患の概要 overview of renal disease associated with malignancy
5. 高リスク妊娠性絨毛腫瘍の初期マネージメント initial management of high risk gestational trophoblastic neoplasia

English Journal

Rictor/mTORC2 signaling mediates TGFβ1-induced fibroblast activation and kidney fibrosis.

Li J1, Ren J1, Liu X1, Jiang L1, He W1, Yuan W2, Yang J1, Dai C3.
Kidney international.Kidney Int.2015 May 13. doi: 10.1038/ki.2015.119. [Epub ahead of print]
The mammalian target of rapamycin (mTOR) was recently identified in two structurally distinct multiprotein complexes: mTORC1 and mTORC2. Previously, we found that Rictor/mTORC2 protects against cisplatin-induced acute kidney injury, but the role and mechanisms for Rictor/mTORC2 in TGFβ1-induced fib
PMID 25970154

Zhou M1, Tang W2, Fu Y1, Xu X2, Wang Z1, Lu Y3, Liu F3, Yang X4, Wei X1, Zhang Y1, Liu J2, Geng X1, Zhang C5, Wan Q6, Li N7, Yi F8.
Kidney international.Kidney Int.2015 May;87(5):918-29. doi: 10.1038/ki.2014.403. Epub 2015 Jan 21.
Progranulin (PGRN), an autocrine growth factor, has multiple physiological functions and is widely involved in the pathogenesis of many types of diseases. The pivotal anti-inflammatory function of PGRN in rheumatoid arthritis encouraged us to examine the role of PGRN in acute kidney injury (AKI). We
PMID 25607110

Melatonin Pre-Treatment of Human Adipose Tissue-Derived Mesenchymal Stromal Cells Enhances their Pro-survival and Protective Effects on Human Kidney Cells.

Zhao J1, Young YK2, Fradette J3, Eliopoulos N4.
American journal of physiology. Renal physiology.Am J Physiol Renal Physiol.2015 Apr 22:ajprenal.00512.2014. doi: 10.1152/ajprenal.00512.2014. [Epub ahead of print]
The efficacy of cell therapy for many diseases can be limited by the poor survival of implanted cells in an environment of tissue injury. Melatonin has been reported to have anti-oxidative and anti-apoptotic effects. Adipose tissue-derived mesenchymal stromal cells (ASCs), cells easily obtained in h
PMID 25904702

Butein Ameliorates Renal Concentrating Ability in Cisplatin-Induced Acute Renal Failure in Rats (Pharmacognosy)

Kang Dae Gill,Lee An Sook,Mun Yeun Ja [他],WOO Won Hong,KIM Youn Chul,SOHN Eun Jin,MOON Mi Kyong,LEE Ho Sub
Biological & pharmaceutical bulletin 27(3), 366-370, 2004-03-01
… The present study examined whether the cisplatin-induced nephropathy could be ameliorated by administration of butein isolated from the stems of Rhus verniciflua STOCKS. … The present study showed that polyuric profile was revealed in cisplatin-induced acute renal failure (ARF) rats associated with decreases in urinary sodium, potassium, chloride, and creatinine excretion, and osmolality. …
NAID 110003608765

Possible role of Ets-1 and MMP-1 in matrix remodeling in experimental cisplatin nephropathy

NAZNEEN Arifa,RAZZAQUE Mohammed S.,LIU Diange,TAGUCHI Takashi
Medical electron microscopy : official journal of the Clinical Electron Microscopy Society of Japan 35(4), 242-247, 2002-12-01
NAID 10012610703

ARAKAWA Masahiro,IICHIKAWA Kazunobu,CHIBA Jun,SASAKI Yasuhiko,AIZAWA Masataka,SATO Hiroshi
Clinical and experimental nephrology 6(1), 58-62, 2002-03-01
NAID 50001095668