慢性胃腸炎
WordNet
- being long-lasting and recurrent or characterized by long suffering; "chronic indigestion"; "a chronic shortage of funds"; "a chronic invalid"
- of long duration; "chronic money problems" (同)continuing
- habitual; "a chronic smoker" (同)inveterate
- inflammation of the stomach and intestines; can be caused by Salmonella enteritidis (同)stomach flu, intestinal flu
PrepTutorEJDIC
- (病気が)長期にわたる,慢性の / 《名詞の前にのみ用いて》常習の,癖になった
- 胃腸炎
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English Journal
- Genetics of ankylosing spondylitis.
- Robinson PC, Brown MA.Author information University of Queensland Diamantina Institute, Translational Research Institute, 37 Kent Road, Princess Alexandra Hospital, Brisbane, Australia.AbstractAnkylosing spondylitis (AS) is a chronic inflammatory arthritis that affects the spine and sacroiliac joints. It causes significant disability and is associated with a number of other features including peripheral arthritis, anterior uveitis, psoriasis and inflammatory bowel disease (IBD). Significant progress has been made in the genetics of AS have in the last five years, leading to new treatments in trial, and major leaps in understanding of the aetiopathogenesis of the disease.
- Molecular immunology.Mol Immunol.2014 Jan;57(1):2-11. doi: 10.1016/j.molimm.2013.06.013. Epub 2013 Jul 31.
- Ankylosing spondylitis (AS) is a chronic inflammatory arthritis that affects the spine and sacroiliac joints. It causes significant disability and is associated with a number of other features including peripheral arthritis, anterior uveitis, psoriasis and inflammatory bowel disease (IBD). Significa
- PMID 23916070
- Algorithm-based management of patients with gastrointestinal symptoms in patients after pelvic radiation treatment (ORBIT): a randomised controlled trial.
- Andreyev HJ1, Benton BE2, Lalji A2, Norton C3, Mohammed K4, Gage H5, Pennert K4, Lindsay JO6.Author information 1The Gastrointestinal Unit, The Royal Marsden NHS Foundation Trust, London and Surrey, UK. Electronic address: j@andreyev.demon.co.uk.2The Gastrointestinal Unit, The Royal Marsden NHS Foundation Trust, London and Surrey, UK.3King's College London and Imperial College Healthcare NHS Trust, London, UK.4Statistics Unit, The Royal Marsden NHS Foundation Trust, London and Surrey, UK.5Deptartment of Economics, University of Surrey, Guildford, UK.6Digestive Diseases Clinical Academic Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, UK.AbstractBACKGROUND: Chronic gastrointestinal symptoms after pelvic radiotherapy are common, multifactorial in cause, and affect patients' quality of life. We assessed whether such patients could be helped if a practitioner followed an investigative and management algorithm, and whether outcomes differed by whether a nurse or a gastroenterologist led this algorithm-based care.
- Lancet.Lancet.2013 Dec 21;382(9910):2084-92. doi: 10.1016/S0140-6736(13)61648-7. Epub 2013 Sep 23.
- BACKGROUND: Chronic gastrointestinal symptoms after pelvic radiotherapy are common, multifactorial in cause, and affect patients' quality of life. We assessed whether such patients could be helped if a practitioner followed an investigative and management algorithm, and whether outcomes differed by
- PMID 24067488
- Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis.
- Alenghat T, Osborne LC, Saenz SA, Kobuley D, Ziegler CG, Mullican SE, Choi I, Grunberg S, Sinha R, Wynosky-Dolfi M, Snyder A, Giacomin PR, Joyce KL, Hoang TB, Bewtra M, Brodsky IE, Sonnenberg GF, Bushman FD, Won KJ, Lazar MA, Artis D.Author information 1] Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA [2] Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA [3] Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.AbstractThe development and severity of inflammatory bowel diseases and other chronic inflammatory conditions can be influenced by host genetic and environmental factors, including signals derived from commensal bacteria. However, the mechanisms that integrate these diverse cues remain undefined. Here we demonstrate that mice with an intestinal epithelial cell (IEC)-specific deletion of the epigenome-modifying enzyme histone deacetylase 3 (HDAC3(ΔIEC) mice) exhibited extensive dysregulation of IEC-intrinsic gene expression, including decreased basal expression of genes associated with antimicrobial defence. Critically, conventionally housed HDAC3(ΔIEC) mice demonstrated loss of Paneth cells, impaired IEC function and alterations in the composition of intestinal commensal bacteria. In addition, HDAC3(ΔIEC) mice showed significantly increased susceptibility to intestinal damage and inflammation, indicating that epithelial expression of HDAC3 has a central role in maintaining intestinal homeostasis. Re-derivation of HDAC3(ΔIEC) mice into germ-free conditions revealed that dysregulated IEC gene expression, Paneth cell homeostasis and intestinal barrier function were largely restored in the absence of commensal bacteria. Although the specific mechanisms through which IEC-intrinsic HDAC3 expression regulates these complex phenotypes remain to be determined, these data indicate that HDAC3 is a critical factor that integrates commensal-bacteria-derived signals to calibrate epithelial cell responses required to establish normal host-commensal relationships and maintain intestinal homeostasis.
- Nature.Nature.2013 Dec 5;504(7478):153-7. doi: 10.1038/nature12687. Epub 2013 Nov 3.
- The development and severity of inflammatory bowel diseases and other chronic inflammatory conditions can be influenced by host genetic and environmental factors, including signals derived from commensal bacteria. However, the mechanisms that integrate these diverse cues remain undefined. Here we de
- PMID 24185009
Japanese Journal
- 症例報告 ノロウイルスの持続感染により反復する胃腸炎と体重増加不良がみられた急性リンパ性白血病の1幼児例
- 西内 律雄,渡邉 宏和,岩﨑 由佳 [他]
- 日本小児血液・がん学会雑誌 = Japanese journal of Pediatric Hematology/Oncology 52(1), 60-65, 2015
- NAID 40020456206
- Successful Treatment with Infliximab for Refractory Uveitis in a Hemodialysis Patient with Behçet's Disease and a Review of the Literature for Infliximab Use in Patients on Hemodialysis
- Kurata Izumi,Tsuboi Hiroto,Takahashi Hidenori,Abe Saori,Ebe Hiroshi,Hagiwara Shinya,Umeda Naoto,Kondo Yuya,Ogishima Hiroshi,Suzuki Takeshi,Matsumoto Isao,Hoshi Sujin,Oshika Tetsuro,Sumida Takayuki
- Internal Medicine 54(12), 1553-1557, 2015
- … A 36-year-old man with a 16-year history of refractory Behçet's disease (BD)-associated uveitis and chronic renal failure requiring hemodialysis suffered from frequent ocular attacks despite treatment with systemic corticosteroids and cyclosporine A. … Although he developed mild acute gastroenteritis, he did not experience any other adverse events. …
- NAID 130005075949
- Clinical Features of Bacteremia due to Campylobacter jejuni
- Mori Takehiko,Hasegawa Naoki,Sugita Kayoko,Shinjoh Masayoshi,Nakamoto Nobuhiro,Shimizu Takayuki,Hori Shingo,Iketani Osamu,Fujiwara Hiroshi,Takano Yaoko,Iwata Satoshi
- Internal Medicine 53(17), 1941-1944, 2014
- … Except for 2 previously healthy individuals, 5 patients had underlying diseases (chronic liver diseases, n=3; … jejuni bacteremia could occur primarily or secondarily to gastroenteritis with a seasonal peak and that prognosis would be favorable regardless of the underlying diseases. …
- NAID 130004685048
Related Pictures
★リンクテーブル★
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- 英
- chronic gastroenteritis
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- 関
- chronically、chronicity