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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/04/11 00:08:22」(JST)

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The term chromophobe, refers to histological structures which do not stain readily, and thus appear more relatively pale under the microscope—hence their "fear" ("phobia") of "color" ("chrome").

Chromophobe cells, also known as amphophils, are epithelial cells found in the anterior and intermediate lobes of the pituitary. They are one of three cell types, the others being basophils and acidophils. Together, these epithelial cells are responsible for producing the hormones of the anterior pituitary and releasing them into the bloodstream.

Melanotrophs (also, melanotropes) are a type of chromophobe, which secrete melanocyte stimulating hormone (MSH).

Cancer

"Chromophobe" also refers to a type of renal cell carcinoma (distinct from "clear cell").^[1]

References

^ ACS :: What Is Kidney Cancer (Renal Cell Carcinoma)?

External links

Chromophobe at eMedicine Dictionary

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UpToDate Contents

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English Journal

Protein expression and gene mutation status of KIT and PDGFRA in renal cell carcinoma.

Terada T.SourceDepartment of Pathology, Shizuoka City Shimizu Hospital, Shizuoka, Japan. piyo0111jp@yahoo.co.jp.
Histology and histopathology.Histol Histopathol.2012 Mar;27(3):297-302.
The author investigated protein expression and gene mutations of KIT and PDGFRA in 61 consecutive surgical cases of renal cell carcinoma (RCC). The cases of RCC consisted of 43 clear cell RCC (CCRCC), 9 chromophobe RCC (ChrRCC), or 9 papillary RCC (PaRCC). Normal distribution of KIT and PDGFRA prote
PMID 22237707

Japanese Journal

Chromophobe renal cell carcinoma, oncocytic variant : a proposal of a new variant giving a critical diagnostic pitfall in diagnosing renal oncocytic tumors

KURODA Naoto,TANAKA Azusa,YAMAGUCHI Tadanori,KASAHARA Kotaro,NARUSE Keishi,YAMADA Yosuke,HATANAKA Kanako,SHINOHARA Nobuo,NAGASHIMA Yoji,MIKAMI Shuji,OYA Mototsugu,HAMASHIMA Takeru,MICHAL Michal,HES Ondrej
Medical molecular morphology : official journal of the Japanese Society for Clinical Molecular Morphology 46(1), 49-55, 2013-03-01
NAID 10031171364

Editorial Comment to Chromophobe renal cell carcinoma : A review of an uncommon entity

STEC Rafal
International journal of urology 19(10), 901-902, 2012-10-01
NAID 10031123324

Chromophobe renal cell carcinoma : A review of an uncommon entity

VERA-BADILLO Francisco Emilio,CONDE Esther,DURAN Ignacio
International journal of urology 19(10), 894-900, 2012-10-01
NAID 10031123323

Related Pictures

American Urological Association - Chromophobe Renal Cell Carcinoma What is Chromophobe Renal Cell Carcinoma? - Cancer Therapy Advisor File:Chromophobe renal cell carcinoma -- high mag.jpg - Wikimedia Commons Pathology Outlines - Eosinophilic variant of chromophobe renal cell carcinoma Histopathology images of Renal cell carcinoma, chromophobe cell type by PathPedia.com