English Journal

Examination of the role of galectins during in vivo angiogenesis using the chick chorioallantoic membrane assay.

Kleibeuker EA1, Schulkens IA, Castricum KC, Griffioen AW, Thijssen VL.
Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2015;1207:305-15. doi: 10.1007/978-1-4939-1396-1_20.
Angiogenesis is a complex multi-process involving various activities of endothelial cells. These activities are influenced in vivo by environmental conditions like interactions with other cell types and the microenvironment. Galectins play a role in several of these interactions and are therefore re
PMID 25253149

Physicochemical characterization and toxicological evaluation of plant-based anionic polymers and their nanoparticulated system for ocular delivery.

Pathak D1, Kumar P, Kuppusamy G, Gupta A, Kamble B, Wadhwani A.
Nanotoxicology.Nanotoxicology.2014 Dec;8(8):843-55. doi: 10.3109/17435390.2013.834996. Epub 2013 Sep 18.
The water-soluble fractions of mucilages and gum from the seeds of fenugreek, isphagula and mango bark exudate were isolated, purified and characterized using X-ray diffraction (XRD) spectrometry, Fourier transform infrared spectroscopy (FT-IR), maldi/GC-MS, elemental analysis, 1D ((1)H and (13)C) a
PMID 23952497

Lange S1, Gonzalez I, Pinto MP, Arce M, Valenzuela R, Aranda E, Elliot M, Alvarez M, Henriquez S, Velasquez EV, Orge F, Oliva B, Gonzalez P, Villalon M, Cautivo KM, Kalergis AM, Pereira K, Mendoza C, Saez C, Kato S, Cuello MA, Parborell F, Irusta G, Palma V, Allende ML, Owen GI.
Journal of cellular physiology.J Cell Physiol.2014 Nov;229(11):1673-80. doi: 10.1002/jcp.24612.
Knockout models have shown that the coagulation system has a role in vascular development and angiogenesis. Herein, we report for the first time that zymogen FX and its active form (FXa) possess anti-angiogenic properties. Both the recombinant FX and FXa inhibit angiogenesis in vitro using endotheli
PMID 24615682