関: choline theophylline

WordNet

a B-complex vitamin that is a constituent of lecithin; essential in the metabolism of fat

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/05/25 11:48:01」(JST)

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Choline theophyllinate (INN), also known as oxtriphylline, is a cough medicine derived from xanthine that acts as a bronchodilator to open up airways in the lung. Chemically, it is a salt of choline and theophylline. It classifies as an expectorant.^{[citation needed]} The drug is available under the brand names Choledyl and Choledyl SA, among others.^[1]

References

^ Drugs.com: Choledyl (oxtriphylline) medical facts

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1. 周術期の投薬マネージメント perioperative medication management
2. 喘息におけるテオフィリン使用 theophylline use in asthma
3. 慢性閉塞性肺疾患（COPD）治療におけるメチルキサンチンの役割 role of methylxanthines in the treatment of copd
4. テオフィリン中毒 theophylline poisoning
5. 慢性閉塞性肺疾患（COPD）における不整脈 arrhythmias in copd

English Journal

Revised FDA labeling guideline for theophylline oral dosage forms.

Hendeles L1, Jenkins J, Temple R.
Pharmacotherapy.Pharmacotherapy.1995 Jul-Aug;15(4):409-27.
PMID 7479193

Chemiluminometric determination of choline-related substances in pharmaceutical preparations by dot-blot.

Luterotti S1, Maysinger D.
Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.1994 Sep;12(9):1083-90.
A simple and reliable method of assaying succinylcholine chloride, oxtriphylline (choline theophyllinate) and acetycholine chloride in pharmaceutical preparations, based on conversion to choline, is provided by combination of chemiluminometry of choline and dot-blot technique. Recoveries of 102 and
PMID 7803556

The effect of steroids on theophylline absorption.

Tatsis G1, Orphanidou D, Douratsos D, Mellissinos C, Pantelakis D, Pipini E, Jordanoglou J.
The Journal of international medical research.J Int Med Res.1991 Jul-Aug;19(4):326-9.
The effect of hydrocortisone on plasma theophylline concentrations was evaluated in 20 patients suffering from chronic bronchitis or stable bronchial asthma. Choline theophyllinate (400 mg) was orally administered every 12 h for 8 days and blood samples were taken every 2 h during the day for the me
PMID 1916006

「コリンテオフィリン」

Systematic (IUPAC) name
	(2-hydroxyethyl)trimethylazanium; 1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-7-ide
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy; category	US: C (Risk not ruled out);
Identifiers
ATC code	R03DA02
PubChem	CID 656652
UNII	3K045XR58X
ChEMBL	CHEMBL1200434
Synonyms	Oxtriphylline, theocolin
Chemical data
Formula	C12H21N5O3
Molecular mass	283.33 g/mol
	SMILES CN1C(=C2C(=NC=N2)N(C1=O)C)[O-].C[N+](C)(C)CCO;
	InChI InChI=1S/C7H8N4O2.C5H14NO/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13;1-6(2,3)4-5-7/h3,12H,1-2H3;7H,4-5H2,1-3H3/q;+1/p-1; Key:SOELXOBIIIBLRJ-UHFFFAOYSA-M ;