コレステロール27-水酸化酵素、コレステロール27-ヒドロキシラーゼ
WordNet
- an animal sterol that is normally synthesized by the liver; the most abundant steroid in animal tissues (同)cholesterin
PrepTutorEJDIC
- コレステロール(胆汁・血液・神経組織などの脂肪性成分)
UpToDate Contents
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English Journal
- Plasma IL-33 in atopic patients correlates with pro-inflammatory cytokines and changes cholesterol transport protein expression: a surprising neutral overall impact on atherogenicity.
- Voloshyna I1, Mucci T, Sher J, Fonacier LS, Littlefield MJ, Carsons S, Reiss AB.
- Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.Clin Exp Allergy.2015 Feb 21. doi: 10.1111/cea.12516. [Epub ahead of print]
- OBJECTIVE: Interleukin (IL)-33 has been associated with atopic and inflammatory conditions. IL-33 may be atheroprotective inducing a Th1-to-Th2 immunologic switch. However, the role of IL-33 in cardiovascular disease remains unclear. This study examines the effect of physiological and elevated IL-33
- PMID 25703059
- Influence of dietary tender cluster beans (Cyamopsis tetragonoloba) on biliary proteins, bile acid synthesis and cholesterol crystal growth in rat bile.
- Raghavendra CK1, Srinivasan K2.
- Steroids.Steroids.2015 Feb;94:21-30. doi: 10.1016/j.steroids.2014.12.003. Epub 2014 Dec 19.
- Tender cluster beans (CBs; Cyamopsis tetragonoloba) are observed to possess anti-lithogenic potential in experimental mice. Formation of cholesterol gallstones in gallbladder is controlled by procrystallizing and anticrystallizing factors present in bile in addition to supersaturation of cholesterol
- PMID 25534812
- [255-POS]: Maternal 27-hydroxycholesterol (27-OHC) concentrations during the course of pregnancy and in pregnancy pathologies.
- Winkler BS1, Kleine-Eggebrecht N1, Maass N1, Mohaupt M2, Escher G2, Pecks U1.
- Pregnancy hypertension.Pregnancy Hypertens.2015 Jan;5(1):128. doi: 10.1016/j.preghy.2014.10.261. Epub 2015 Feb 23.
- OBJECTIVES: 27-hydroxycholesterol (27-OHC) is the hydroxylation product of cholesterol by the enzyme sterol 27-hydroxylase (CYP27A1). 27-OHC is a potent inhibitor of cholesterol synthesis and increases cholesterol efflux from extrahepatic cells in vitro. Its transport from peripheral cells to the li
- PMID 25787605
Japanese Journal
- Hypocholesterolemic Mechanism of Chlorella : Chlorella and Its Indigestible Fraction Enhance Hepatic Cholesterol Catabolism through Up-Regulation of Cholesterol 7α-Hydroxylase in Rats
- Shibata Shinya,Hayakawa Kazuhito,Egashira Yukari [他],SANADA Hiroo
- Bioscience, biotechnology, and biochemistry 71(4), 916-925, 2007-04-23
- … however, its effects on hepatic cholesterol metabolism are still unclear. … In the present study, male Wistar rats were divided into four groups and fed a high sucrose + 10% lard diet (H), an H + 10% CP diet (H+CP), an H + 0.5% cholesterol + 0.25% sodium cholate diet (C), or a C + 10% CP diet (C+CP) for 2 weeks. … CP decreased serum and liver cholesterol levels significantly in rats fed C-based diets, but did not affect these parameters in rats fed H-based diets. …
- NAID 10027513400
- Enhanced Susceptibility of LDL to Oxidative Modification in a CTX Patient:-Role of Chenodeoxycholic Acid in Xanthoma Formation-
- Kinoshita Makoto,Kawamura Mitsunobu,Fujita Mineko,Hirota Daisuke,Suda Takaoki,Taki Masanari,Kusano Jyun,Takao Kosuke,Takenaka Hideki,Kubota Shunichiro,Teramoto Tamio
- Journal of Atherosclerosis and Thrombosis 11(3), 167-172, 2004
- … The underlying biochemical defect is a lack of the hepatic mitochondrial cholesterol 27-hydroxylase involved in the normal biosynthesis of bile acid, resulting in reduced biosynthesis of chenodeoxycholic acid (CDCA). … The present study investigated the effect of CDCA on the mechanism of cholesterol accumulation in macrophages, the major cells in xanthoma. …
- NAID 130004444106
- Mechanism of accumulation of cholesterol and cholestanol in tendons and the role of sterol 27-hydroxylase (CYP27A1)
Related Links
- "Human sterol 27-hydroxylase (CYP27) overexpressor transgenic mouse model. Evidence against 27-hydroxycholesterol as a critical regulator of cholesterol homeostasis". J. Biol. Chem. 277 (37): 34036–41. doi:10.1074/jbc.M201122200.
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★リンクテーブル★
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- 英
- cholesterol 27-hydroxylase
- 関
- コレステロール27-ヒドロキシラーゼ
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- 英
- cholesterol 27-hydroxylase
- 関
- コレステロール27-水酸化酵素
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コレステロール