WordNet

an animal sterol that is normally synthesized by the liver; the most abundant steroid in animal tissues (同)cholesterin

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1. LDLコレステロール代謝の遺伝性疾患 inherited disorders of ldl cholesterol metabolism
2. HDLコレステロール：異常値の臨床的側面 hdl cholesterol clinical aspects of abnormal values
3. 二次予防における脂質（高コレステロール血症を含む）の治療 treatment of lipids including hypercholesterolemia in secondary prevention
4. 脳腱黄色腫症 cerebrotendinous xanthomatosis
5. 心血管疾患または糖尿病患者におけるコレステロール低下に関する臨床試験 clinical trials of cholesterol lowering in patients with cardiovascular disease or diabetes

Plasma IL-33 in atopic patients correlates with pro-inflammatory cytokines and changes cholesterol transport protein expression: a surprising neutral overall impact on atherogenicity.

Voloshyna I1, Mucci T, Sher J, Fonacier LS, Littlefield MJ, Carsons S, Reiss AB.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.Clin Exp Allergy.2015 Feb 21. doi: 10.1111/cea.12516. [Epub ahead of print]
OBJECTIVE: Interleukin (IL)-33 has been associated with atopic and inflammatory conditions. IL-33 may be atheroprotective inducing a Th1-to-Th2 immunologic switch. However, the role of IL-33 in cardiovascular disease remains unclear. This study examines the effect of physiological and elevated IL-33
PMID 25703059

Influence of dietary tender cluster beans (Cyamopsis tetragonoloba) on biliary proteins, bile acid synthesis and cholesterol crystal growth in rat bile.

Raghavendra CK1, Srinivasan K2.
Steroids.Steroids.2015 Feb;94:21-30. doi: 10.1016/j.steroids.2014.12.003. Epub 2014 Dec 19.
Tender cluster beans (CBs; Cyamopsis tetragonoloba) are observed to possess anti-lithogenic potential in experimental mice. Formation of cholesterol gallstones in gallbladder is controlled by procrystallizing and anticrystallizing factors present in bile in addition to supersaturation of cholesterol
PMID 25534812

[255-POS]: Maternal 27-hydroxycholesterol (27-OHC) concentrations during the course of pregnancy and in pregnancy pathologies.

Winkler BS1, Kleine-Eggebrecht N1, Maass N1, Mohaupt M2, Escher G2, Pecks U1.
Pregnancy hypertension.Pregnancy Hypertens.2015 Jan;5(1):128. doi: 10.1016/j.preghy.2014.10.261. Epub 2015 Feb 23.
OBJECTIVES: 27-hydroxycholesterol (27-OHC) is the hydroxylation product of cholesterol by the enzyme sterol 27-hydroxylase (CYP27A1). 27-OHC is a potent inhibitor of cholesterol synthesis and increases cholesterol efflux from extrahepatic cells in vitro. Its transport from peripheral cells to the li
PMID 25787605

Hypocholesterolemic Mechanism of Chlorella : Chlorella and Its Indigestible Fraction Enhance Hepatic Cholesterol Catabolism through Up-Regulation of Cholesterol 7α-Hydroxylase in Rats

Shibata Shinya,Hayakawa Kazuhito,Egashira Yukari [他],SANADA Hiroo
Bioscience, biotechnology, and biochemistry 71(4), 916-925, 2007-04-23
… however, its effects on hepatic cholesterol metabolism are still unclear. … In the present study, male Wistar rats were divided into four groups and fed a high sucrose + 10% lard diet (H), an H + 10% CP diet (H+CP), an H + 0.5% cholesterol + 0.25% sodium cholate diet (C), or a C + 10% CP diet (C+CP) for 2 weeks. … CP decreased serum and liver cholesterol levels significantly in rats fed C-based diets, but did not affect these parameters in rats fed H-based diets. …
NAID 10027513400

Enhanced Susceptibility of LDL to Oxidative Modification in a CTX Patient:-Role of Chenodeoxycholic Acid in Xanthoma Formation-

Kinoshita Makoto,Kawamura Mitsunobu,Fujita Mineko,Hirota Daisuke,Suda Takaoki,Taki Masanari,Kusano Jyun,Takao Kosuke,Takenaka Hideki,Kubota Shunichiro,Teramoto Tamio
Journal of Atherosclerosis and Thrombosis 11(3), 167-172, 2004
… The underlying biochemical defect is a lack of the hepatic mitochondrial cholesterol 27-hydroxylase involved in the normal biosynthesis of bile acid, resulting in reduced biosynthesis of chenodeoxycholic acid (CDCA). … The present study investigated the effect of CDCA on the mechanism of cholesterol accumulation in macrophages, the major cells in xanthoma. …
NAID 130004444106