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any of various organs that synthesize substances needed by the body and release it through ducts or directly into the bloodstream (同)secretory organ, secretor, secreter
relating to or secreting cerumen

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(生物体内の)腺(せん)

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/04/18 14:59:43」(JST)

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Ceruminous glands are specialized sudoriferous glands (sweat glands) located subcutaneously in the external auditory canal. Ceruminous glands are simple, coiled, tubular glands made up of an inner secretory layer of cells and an outer myoepithelial layer of cells.^[1] They are classed as apocrine glands. The glands drain into larger ducts, which then drain into the guard hairs that reside in the external auditory canal.^[2] Here they produce cerumen, or earwax, by mixing their secretion with sebum and dead epidermal cells. Cerumen keeps the eardrum pliable, lubricates and cleans the external auditory canal, waterproofs the canal, kills bacteria, and serves as a barrier to trap foreign particles (dust, fungal spores, etc.) by coating the guard hairs of the ear, making them sticky.^[1]

These glands are capable of developing both benign and malignant tumors. The benign tumors include ceruminous adenoma, ceruminous pleomorphic adenoma, and ceruminous syringocystadenoma papilliferum. The malignant tumors include ceruminous adenocarcinoma, adenoid cystic carcinoma, and mucoepidermoid carcinoma.^[2]

References

^ ^a ^b Saladin,Kenneth. Anatomy & Physiology: The Unity of Form and Function, Fifth Edition. McGraw-Hill. 2010^{[page needed]}
^ ^a ^b Pathology of Ceruminous Gland Tumors of the External Auditory Canal at eMedicine

External links

http://www.anatomyatlases.org/MicroscopicAnatomy/Section07/Plate07142.shtml^{[full citation needed]}

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1. 副甲状腺の外科解剖学 surgical anatomy of the parathyroid glands
2. 耳垢 cerumen
3. 原発性副甲状腺機能亢進症の副甲状腺診査 parathyroid exploration for primary hyperparathyroidism
4. 外陰膿瘍 vulvar abscess
5. 食道の良性病変 benign lesions of the esophagus

English Journal

Ceruminous adenoma (ceruminoma) arising in a nevus sebaceus of Jadassohn within the external auditory canal of a 3 year-old boy - A case report.

Niemczyk E1, Niemczyk K2, Małdyk J3, Zawadzka-Głos L4.
International journal of pediatric otorhinolaryngology.Int J Pediatr Otorhinolaryngol.2015 Jul 20. pii: S0165-5876(15)00354-7. doi: 10.1016/j.ijporl.2015.07.019. [Epub ahead of print]
Nevus sebaceus of Jadassohn is a congenital yellowish hairless skin lesion, mainly located on the head and neck. A common phenomenon is the coexistence of secondary tumors within the lesion. These are mainly benign tumors, the majority of which are trichoblastoma and syringocystadenoma papilliferum.
PMID 26307545

Coordinate expression of cytokeratins 7 and 14, vimentin, and Bcl-2 in canine cutaneous epithelial tumors and cysts.

Pieper JB1, Stern AW2, LeClerc SM2, Campbell KL2.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc.J Vet Diagn Invest.2015 Jul;27(4):497-503. doi: 10.1177/1040638715594115. Epub 2015 Jul 16.
Forty-seven canine cutaneous epithelial tumors and cysts were examined to determine coordinate expression of cytokeratins 7 (CK7) and 14 (CK14), vimentin, and Bcl-2 using commercially available antibodies. Within non-affected normal skin adjacent to tumors or cysts, CK7 expression was observed in lu
PMID 26185124

Identification of volatile organic compounds in human cerumen.

Prokop-Prigge KA1, Thaler E2, Wysocki CJ3, Preti G4.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.J Chromatogr B Analyt Technol Biomed Life Sci.2014 Mar 15;953-954:48-52. doi: 10.1016/j.jchromb.2014.01.043. Epub 2014 Feb 5.
We report here the initial examination of volatile organic compounds (VOCs) emanating from human earwax (cerumen). Recent studies link a single nucleotide polymorphism (SNP) in the adenosine triphosphate (ATP) binding cassette, sub-family C, member 11 gene (ABCC11) to the production of different typ
PMID 24572763

Japanese Journal

両側外耳道に耳垢腺癌が同時発生した若齢猫の1例

山田茂夫,加山英,徳田雅史,立野祐子,相内聖峰
獣医臨床皮膚科 18(2), 99-102, 2012
両耳の外耳道に耳垢腺癌が同時発生した1歳，スコティッシュホールドを経験した。肉眼所見として，左外耳道には5 mm径の自壊した出血性暗色丘疹，右には隣接した各3 mm径の暗赤色および黒色丘疹がそれぞれ外耳道開口部内側皮膚のほぼ同位置に観察された。両耳に外耳炎は認められなかった。病理組織学検査では左右ともに耳垢腺が強い異型性と浸潤性を有し，大小の塊状に乳頭状―腺様増殖していた。この結果から，両耳共に丘 …
NAID 130004494319

A strong association of axillary osmidrosis with the wet earwax type determined by genotyping of the ABCC11 gene.

Nakano Motoi,Miwa Nobutomo,Hirano Akiyoshi,Yoshiura Koh-Ichiro,Niikawa Norio
BMC genetics 10, 42, 2009-08-04
… BACKGROUND: Two types of cerumen occur in humans: the wet type with brownish, sticky earwax, and the dry type with a lack of or reduced ceruminous secretion. … AO was defined here as a clinical condition of individuals with a deep anxiety regarding axillary odor and had undergone the removal of bilateral axillary apocrine glands. …
NAID 120001609360

幼少時より認めたＦｅｌｉｎｅ　Ｃｅｒｕｍｉｎｏｕｓ　Ｃｙｓｔｏｍａｔｏｓｉｓの１例

村山信雄,榊原一夫,永田雅彦
獣医臨床皮膚科 12(4), 239-241, 2006
… 以上よりFeline ceruminous cystomatosisと診断した。 …
NAID 130004494266

「耳道腺」

　　[★]

英: ceruminous glands
同: 耳垢腺
関: 外耳道

[Saladin-1] Saladin,Kenneth. Anatomy & Physiology: The Unity of Form and Function, Fifth Edition. McGraw-Hill. 2010^{[page needed]}

[Medscape-2] Pathology of Ceruminous Gland Tumors of the External Auditory Canal at eMedicine

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ceruminous glands