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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/02/25 22:46:25」(JST)

Cefuzonam (INN) is a second-generation cephalosporin antibiotic.

References

Hara K, Matsumoto F (December 1987). "[New antimicrobial agent series XXVIII: cefuzonam]". Jpn J Antibiot (in Japanese) 40 (12): 1953–63. PMID 3329242.

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The excretion of cephem antibiotics into saliva is inversely associated with their plasma protein-binding activities.

Hamada T, Ueta E, Kodama H, Osaki T.SourceDepartment of Oral Surgery, Kochi Medical School, Nankoku-city, Kochi, Japan. a/o/o@liml.ocn.ne.jp
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology.J Oral Pathol Med.2002 Feb;31(2):109-16.
BACKGROUND: The excretion of medicated drugs into saliva may disturb the oral environment and antibiotic excretion into saliva appears to be regulated by many factors that have not been fully explored.METHODS: Excretion of four cephem antibiotics into saliva was examined in healthy volunteers and ra
PMID 11896833

Cloning and sequencing of the gene encoding Toho-2, a class A beta-lactamase preferentially inhibited by tazobactam.

Ma L, Ishii Y, Ishiguro M, Matsuzawa H, Yamaguchi K.SourceDepartment of Microbiology, Toho University School of Medicine, Tokyo, Japan.
Antimicrobial agents and chemotherapy.Antimicrob Agents Chemother.1998 May;42(5):1181-6.
Escherichia coli TUM1083, which is resistant to ampicillin, carbenicillin, cephaloridine, cephalothin, piperacillin, cefuzonam, and aztreonam while being sensitive to cefoxitin, moxalactam, cefmetazole, ceftazidime, and imipenem, was isolated from the urine of a patient treated with beta-lactam anti
PMID 9593147

壺内英継,辻浩一,安村貢一,石川廣
Chemical & pharmaceutical bulletin 42(10), 2084-2089, 1994-10-15
… Among them, the derivatives having a [2-(2-aminothiazol-4-yl)-2-(Z)-cyclopentyloxyimino]acetamido group at the 7-position characteristically showed potent activities against gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA) and Enterococcus faecalis as compared with cefuzonam and cefmenoxime, which are third-generation cephalosporins. …
NAID 110003630786

Evaluation of minocycline and cefuzonam for antimicrobial activity against clinical isolates

リンク元	「セフゾナム」
拡張検索	「cefuzonam sodium」

Cefuzonam
Systematic (IUPAC) name
	(6R,7R)-7-([(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino)-8-oxo-3-(thiadiazol-5-ylsulfanylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Clinical data
Legal status	℞ (Prescription only);
Identifiers
CAS Number	82219-78-1
ATC code	None
PubChem	CID 6336505
ChemSpider	4891670
UNII	860MT00T7T
KEGG	D03432
ChEMBL	CHEMBL1689069
Chemical data
Formula	C16H15N7O5S4
Molar mass	513.59 g/mol
	SMILES CON=C(C1=CSC(=N1)N)C(=O)NC2C3N(C2=O)C(=C(CS3)CSC4=CN=NS4)C(=O)O ;
	InChI InChI=1S/C16H15N7O5S4/c1-28-21-9(7-5-31-16(17)19-7)12(24)20-10-13(25)23-11(15(26)27)6(4-30-14(10)23)3-29-8-2-18-22-32-8/h2,5,10,14H,3-4H2,1H3,(H2,17,19)(H,20,24)(H,26,27)/b21-9-/t10-,14-/m1/s1 ; Key:CXHKZHZLDMQGFF-ZSDSSEDPSA-N ;
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