WordNet

very thin and insubstantial; "thin paper"; "light summer dresses"
make lighter or brighter; "This lamp lightens the room a bit" (同)illume, illumine, light_up, illuminate
a condition of spiritual awareness; divine illumination; "follow Gods light" (同)illumination
having abundant light or illumination; "they played as long as it was light"; "as long as the lighting was good" (同)lighting
(physics) electromagnetic radiation that can produce a visual sensation; "the light was filtered through a soft glass window" (同)visible_light, visible_radiation
any device serving as a source of illumination; "he stopped the car and turned off the lights" (同)light_source
the visual effect of illumination on objects or scenes as created in pictures; "he could paint the lightest light and the darkest dark" (同)lightness
a particular perspective or aspect of a situation; "although he saw it in a different light, he still did not understand"
a person regarded very fondly; "the light of my life"
a visual warning signal; "they saw the light of the beacon"; "there was a light at every corner"
an illuminated area; "he stepped into the light"
mental understanding as an enlightening experience; "he finally saw the light"; "can you shed light on this problem?"
public awareness; "it brought the scandal to light"
(used of color) having a relatively small amount of coloring agent; "light blue"; "light colors such as pastels"; "a light-colored powder" (同)light-colored
moving easily and quickly; nimble; "the dancer was light and graceful"; "a lightsome buoyant step"; "walked with a light tripping step" (同)lightsome, tripping
having relatively few calories; "diet cola"; "light (or lite) beer"; "lite (or light) mayonnaise"; "a low-cal diet" (同)lite, low-cal, calorie-free
less than the correct or legal or full amount often deliberately so; "a light pound"; "a scant cup of sugar"; "regularly gives short weight" (同)scant, short
(of sleep) easily disturbed; "in a light doze"; "a light sleeper"; "a restless wakeful night" (同)wakeful
(physics, chemistry) not having atomic weight greater than average; "light water is ordinary water"
(used of soil) loose and large-grained in consistency; "light soil"
characterized by or emitting light; "a room that is light when the shutters are open"; "the inside of the house was airy and light"
demanding little effort; not burdensome; "light housework"; "light exercise"
designed for ease of movement or to carry little weight; "light aircraft"; "a light truck"
easily assimilated in the alimentary canal; not rich or heavily seasoned; "a light diet"
having little importance; "losing his job was no light matter"
intended primarily as entertainment; not serious or profound; "light verse"; "a light comedy"
not great in degree or quantity or number; "a light sentence"; "a light accent"; "casualties were light"; "light snow was falling"; "light misty rain"; "light smoke from the chimney"
of comparatively little physical weight or density; "a light load"; "magnesium is a light metal--having a specific gravity of 1.74 at 20 degrees C"
of little intensity or power or force; "the light touch of her fingers"; "a light breeze"
of the military or industry; using (or being) relatively small or light arms or equipment; "light infantry"; "light cavalry"; "light industry"; "light weapons"
psychologically light; especially free from sadness or troubles; "a light heart"
fasten or secure with chains; "Chain the chairs together"
a unit of length
a necklace made by a stringing objects together; "a string of beads"; "a strand of pearls"; (同)string, strand
a linked or connected series of objects; "a chain of daisies"
a series of (usually metal) rings or links fitted into one another to make a flexible ligament
anything that acts as a restraint
(chemistry) a series of linked atoms (generally in an organic molecule) (同)chemical chain
a series of things depending on each other as if linked together; "the chain of command"; "a complicated concatenation of circumstances" (同)concatenation
(business) a number of similar establishments (stores or restaurants or banks or hotels or theaters) under one ownership
connect or arrange into a chain by linking
apparatus for supplying artificial light effects for the stage or a film
the craft of providing artificial light; "an interior decorator must understand lighting"
of or relating to the heart; "cardiac arrest"
British biochemist (born in Germany) who isolated and purified penicillin, which had been discovered in 1928 by Sir Alexander Fleming (1906-1979) (同)Ernst Boris Chain, Sir Ernst Boris Chain

PrepTutorEJDIC

〈U〉『光,光線』;明るさ / 〈U〉夜明け;日中;日光 / 〈C〉『明かり』(太陽・灯火など光を出すもの) / 〈U〉《時にa~》光輝(brightness),(目などの)輝き / 〈C〉(点火するための)火,火花 / 〈C〉明かり採り,採光窓 / 〈C〉《通例単数形で》(絵などの)明るい部分 / 〈U〉(…についての)知識,情報,理解《+『on』+『名』》 / 〈C〉(ものを見る)観点,見地;相 / 〈C〉この世に光を与える人;指導的な人物 / …‘に'『火をつける』《+『up』+『名』+『名』+『up』》 / …‘に'『明かりをつける』,‘を'照らす《+『up』+『名,』+『名』+『up』》 / 〈人〉‘を'明かりをつけて案内する / 〈表情など〉‘を'明るくする《+『up』+『名,』+『名』+『up』》 / 〈物が〉火がつく,点火する;明かりがつく《+『up』》 / 明るくなる,晴れ晴れする《+『up』》 / 『明るい』 / (色が)『薄い』
(重量が)『軽い』 / (いろいろな事について,その程座・量が)軽い,小さい / 『軽快な』 / 軽装の / 肩のこらない;気軽な / 手軽な,骨の折れなし / (食べ物が)消化のよい,もたれない / ふらふらする,目まいのする / アルコール分の少ない / (パンなどが)ふんわりした / (重量が)軽く / (程度が)軽く,容易に;軽装で
(車・馬などから)降りる《+『from』+『名』》(alight) / (木などに)〈鳥などが〉止まる《+『on』(『upon』)+『名』》 / (…に)〈打撃・運などが〉突然ふりかかる《+『on』(『upon』)+『名』》
『鎖』;(装飾用の)鎖 / 《複数形で》『束縛』,拘束;囚人をつなぐ鎖 / (物事の)『連続』,つながり《+『of』+『名』》 / (商店・銀行・ホテルなどの)チェーン(一連の店が同一資本のもとで連携して経営される方式;その店) / チェーン(測量で用いられる単位;約21.7m) / …'を'『鎖でつなぐ』《+『up』(『together』)+『名,』+『名』+『up』(『together』)》
照明,点火 / 照明方法(装置)
心臓の

UpToDate Contents

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1. 肥大型心筋症の遺伝学 genetics of hypertrophic cardiomyopathy
2. Classification of atrial septal defects (ASDs), and clinical features and diagnosis of isolated ASDs in children
3. 肥大型心筋症の自然経過 natural history of hypertrophic cardiomyopathy
4. 心筋障害のバイオマーカーとしてのトロポニンおよびクレアチンキナーゼ troponins and creatine kinase as biomarkers of cardiac injury
5. 急性心臓同種移植拒絶反応：診断 acute cardiac allograft rejection diagnosis

English Journal

Mutations of NKX2.5 and GATA4 genes in the development of congenital heart disease.

Tong YF1.
Gene.Gene.2016 Aug 15;588(1):86-94. doi: 10.1016/j.gene.2016.04.061. Epub 2016 May 3.
OBJECTIVE: To investigate the mutations of NKX2.5 and GATA4 genes in the development of CHD in Chinese population.METHODS: Between December 2010 and December 2014, 185 cases of CHD patients and 210 cases of healthy people were enrolled. NKX2.5 and GATA4 gene mutations and gene expression were detect
PMID 27154817

CaMKII and at least two unidentified kinases phosphorylate regulatory light chain in non-contracting cardiomyocytes.

Eikemo H1, Moltzau LR2, Nguyen CH3, Levy FO4, Skomedal T5, Osnes JB6.
Biochemical and biophysical research communications.Biochem Biophys Res Commun.2016 Aug 12;477(1):14-9. doi: 10.1016/j.bbrc.2016.05.138. Epub 2016 May 27.
In cardiac tissue, regulatory light chain (RLC, myosin light chain 2) phosphorylation (Ser(15)) leads to modulation of muscle contraction through Ca(2+)-sensitization. To elucidate which kinases that are involved in the basal (diastolic phase) RLC phosphorylation, we studied non-contracting adult ra
PMID 27237977

Cardiac myosin light chain is phosphorylated by Ca2+/calmodulin-dependent and -independent kinase activities.

Chang AN1, Mahajan P2, Knapp S3, Barton H4, Sweeney HL5, Kamm KE6, Stull JT6.
Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2016 Jul 5;113(27):E3824-33. doi: 10.1073/pnas.1600633113. Epub 2016 Jun 20.
The well-known, muscle-specific smooth muscle myosin light chain kinase (MLCK) (smMLCK) and skeletal muscle MLCK (skMLCK) are dedicated protein kinases regulated by an autoregulatory segment C terminus of the catalytic core that blocks myosin regulatory light chain (RLC) binding and phosphorylation
PMID 27325775