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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/06/29 21:18:19」(JST)

English Journal

A Small Molecule Pyrazolo[3,4-d]pyrimidinone Inhibitor of Zipper-Interacting Protein Kinase Suppresses Calcium Sensitization of Vascular Smooth Muscle.

MacDonald JA1, Sutherland C2, Carlson DA3, Bhaidani S2, Al-Ghabkari A2, Sward K4, Haystead TA3, Walsh MP2.
Molecular pharmacology.Mol Pharmacol.2015 Oct 13. pii: mol.115.100529. [Epub ahead of print]
A novel inhibitor of zipper-interacting protein kinase (ZIPK) was utilized to examine the involvement of ZIPK in the regulation of smooth muscle contraction. Pre-treatment of de-endothelialized rat caudal arterial smooth muscle strips with the pyrazolo[3,4-d]pyrimidinone inhibitor HS38 decreased the
PMID 26464323

Combination of zoledronic acid and serine/threonine phosphatase inhibitors induces synergistic cytotoxicity and apoptosis in human breast cancer cells via inhibition of PI3K/Akt pathway.

Surmeli Z1, Gursoy P1, Erdogan AP1, Bozkurt E2, Atmaca H2, Uzunoglu S2, Sezgin C1, Şanlı UA1, Uslu R1, Karaca B3.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.Tumour Biol.2015 Oct 13. [Epub ahead of print]
The aim of this study was to investigate the cytotoxic and apoptotic effects of zoledronic acid (ZA) in combination with serine/threonine protein phosphatase inhibitors, calyculin-A (CA) and okadaic acid (OA), in human MCF-7 and MDA-MB-231 breast cancer cells. XTT cell viability assay was used to ev
PMID 26462835

Propofol ameliorates endothelial inflammation induced by hypoxia/reoxygenation in human umbilical vein endothelial cells: Role of phosphatase A2.

Zhu M1, Ding J1, Jiang H1, Kong L1, Sun Z1, Chen J1, Miao C2.
Vascular pharmacology.Vascul Pharmacol.2015 Oct;73:149-57. doi: 10.1016/j.vph.2015.06.002. Epub 2015 Jun 10.
Hypoxia/reoxygenation (H/R) induces endothelial inflammation with augmentation of endothelial adhesion molecules over-expression. Propofol was reported to attenuate endothelial adhesion molecule expression in some situations. Here, we examined the molecular mechanism for how propofol restored H/R-me
PMID 26070526

Prematurely Condensed Chromosome Rings after Neutron Irradiation of Human Lymphocytes

Negative feedback regulation of microbe-associated molecular pattern-induced cytosolic Ca^<2+> transients by protein phosphorylation

Kurusu Takamitsu,Hamada Haruyasu,Sugiyama Yoshimi [他],YAGAWA Toshikazu,KADOTA Yasuhiro,FURUICHI Takuya,HAYASHI Teruyuki,UMEMURA Kenji,KOMATSU Setsuko,MIYAO Akio,HIROCHIKA Hirohiko,KUCHITSU Kazuyuki
Journal of plant research 124(3), 415-424, 2011-05-01
NAID 10028258282

リンク元	「カリクリン」「カリキュリン」

Calyculin
Identifiers
PubChem	10909255
ChemSpider	9084513
ChEMBL	CHEMBL384277
	InChI InChI=1S/C50H81N4O15P/c1-29(20-22-51)16-14-17-30(2)32(4)24-33(5)42(57)35(7)38(55)25-41(65-13)45-46(69-70(61,62)63)49(8,9)50(68-45)26-39(56)34(6)40(67-50)19-15-18-36-27-66-48(53-36)31(3)21-23-52-47(60)44(59)43(58)37(28-64-12)54(10)11/h14-18,20,24,27,31,33-35,37-46,55-59H,19,21,23,25-26,28H2,1-13H3,(H,52,60)(H2,61,62,63)/b16-14+,18-15+,29-20-,30-17+,32-24+/t31-,33+,34-,35-,37-,38-,39+,40-,41-,42+,43-,44-,45+,46-,50+/m1/s1 ; Key: FKAWLXNLHHIHLA-LIKMAGLISA-N ;
Properties
Molecular formula	C51H83N4O15P
Molar mass	1023.2 g/mol
	Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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	Infobox references