The large GTPase Mx1 is involved in apical transport of MDCK cells.
Hoff F1, Greb C, Hollmann C, Hönig E, Jacob R.
Traffic (Copenhagen, Denmark).Traffic.2014 Jun 16. doi: 10.1111/tra.12186. [Epub ahead of print]
In epithelial cells apical proteins are transported by specific transport carriers to the correct membrane domain. The composition of these carriers is heterogeneous and comprises components like motor proteins, annexins, lectins, Rab-GTPases and cargo molecules. Here, we provide biochemical and flu
Down-regulating annexin gene GhAnn2 inhibits cotton fiber elongation and decreases Ca2+ influx at the cell apex.
Tang W1, He Y, Tu L, Wang M, Li Y, Ruan YL, Zhang X.
Plant molecular biology.Plant Mol Biol.2014 Jun 3. [Epub ahead of print]
Cotton fiber is a single cell that differentiates from the ovule epidermis and undergoes synchronous elongation with high secretion and growth rate. Apart from economic importance, cotton fiber provides an excellent single-celled model for studying mechanisms of cell-growth. Annexins are Ca2+- and p
Tumor cell-expressed SerpinB2 is present on microparticles and inhibits metastasis.
Schroder WA1, Major LD, Le TT, Gardner J, Sweet MJ, Janciauskiene S, Suhrbier A.
Cancer medicine.Cancer Med.2014 Jun;3(3):500-13. doi: 10.1002/cam4.229. Epub 2014 Mar 19.
Expression of SerpinB2 (plasminogen activator inhibitor type 2/PAI-2) by certain cancers is associated with a favorable prognosis. Although tumor-associated host tissues can express SerpinB2, no significant differences in the growth of a panel of different tumors in SerpinB2(-/-) and SerpinB2(+/+) m
Calpactin information including symptoms, causes, diseases, symptoms, treatments, and other medical and health issues. ... Terms associated with Calpactin: The following terms can be used for Calpactin annexin Source: CRISP