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English Journal

Effects of Adding Chymosin to Milk on Calcium Homeostasis: A Randomized, Double-Blind, Cross-Over Study.

Møller UK1, Jensen LT, Mosekilde L, Rejnmark L.
Calcified tissue international.Calcif Tissue Int.2014 Dec 18. [Epub ahead of print]
Calcium intake and absorption is important for bone health. In a randomized double-blind cross-over trial, we investigated effects of adding chymosin to milk on the intestinal calcium absorption as measured by renal calcium excretion and indices of calcium homeostasis. The primary outcome of the stu
PMID 25515208

The parathyroid hormone-regulated transcriptome in osteocytes: Parallel actions with 1,25-dihydroxyvitamin D3 to oppose gene expression changes during differentiation and to promote mature cell function.

St John HC1, Meyer MB1, Benkusky NA1, Carlson AH1, Prideaux M2, Bonewald LF2, Wesley Pike J3.
Bone.Bone.2014 Nov 22;72C:81-91. doi: 10.1016/j.bone.2014.11.010. [Epub ahead of print]
Although localized to the mineralized matrix of bone, osteocytes are able to respond to systemic factors such as the calciotropic hormones 1,25(OH)2D3 and PTH. In the present studies, we examined the transcriptomic response to PTH in an osteocyte cell model and found that this hormone regulated an e
PMID 25460572

Low calcium-phosphate intakes modulate the low-protein diet-related effect on peak bone mass acquisition: a hormonal and bone strength determinants study in female growing rats.

Fournier C1, Rizzoli R, Ammann P.
Endocrinology.Endocrinology.2014 Nov;155(11):4305-15. doi: 10.1210/en.2014-1308. Epub 2014 Aug 22.
Peak bone mass acquisition is influenced by environmental factors including dietary intake. A low-protein diet delays body and skeletal growth in association with a reduction in serum IGF-1 whereas serum FGF21 is increased by selective amino acid deprivation. Calcium (Ca) and phosphorous (P) are als
PMID 25147979