English Journal

Determination of the inhibitory potential of 6 fluoroquinolones on CYP1A2 and CYP2C9 in human liver microsomes.

Zhang L1, Wei MJ, Zhao CY, Qi HM.
Acta pharmacologica Sinica.Acta Pharmacol Sin.2008 Dec;29(12):1507-14. doi: 10.1111/j.1745-7254.2008.00908.x.
AIM: To determine the inhibitory potential of 2 new fluoroquinolones, caderofloxacin and antofloxacin, together with 4 marketed fluoroquinolones, moxifloxacin, gatifloxacin, levofloxacin, and ciprofloxacin, on the activity of cytochrome P450 isoforms 1A2 (CYP1A2) and 2C9 (CYP2C9).METHODS: Probe subs
PMID 19026171

[Transfer of cadrofloxacin, a novel fluoroquinolone antibacterial, into the gallbladder tissue and bile].

Tanimura H1, Ohnishi H.
The Japanese journal of antibiotics.Jpn J Antibiot.2004 Feb;57(1):118-23.
Clinical pharmacological studies of a novel fluoroquinolone antibacterial drug, cadrofloxacin, were performed in 12 surgical patients by investigating the transfer of cadrofloxacin into the gallbladder tissue and bile. They were scheduled for cholecystectomy (n = 6) or had undergone a percutaneous t
PMID 15116576