AIM: To determine the inhibitory potential of 2 new fluoroquinolones, caderofloxacin and antofloxacin, together with 4 marketed fluoroquinolones, moxifloxacin, gatifloxacin, levofloxacin, and ciprofloxacin, on the activity of cytochrome P450 isoforms 1A2 (CYP1A2) and 2C9 (CYP2C9).METHODS: Probe subs
[Transfer of cadrofloxacin, a novel fluoroquinolone antibacterial, into the gallbladder tissue and bile].
Tanimura H1, Ohnishi H.
The Japanese journal of antibiotics.Jpn J Antibiot.2004 Feb;57(1):118-23.
Clinical pharmacological studies of a novel fluoroquinolone antibacterial drug, cadrofloxacin, were performed in 12 surgical patients by investigating the transfer of cadrofloxacin into the gallbladder tissue and bile. They were scheduled for cholecystectomy (n = 6) or had undergone a percutaneous t