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1. 幼児および小児における嚥下障害による誤嚥 aspiration due to swallowing dysfunction in infants and children

English Journal

Mitogen-activated Protein Kinase Phosphatase-1 Modulates Regional Effects of Injurious Mechanical Ventilation in Rodent Lungs.

Park MS, He Q, Edwards MG, Sergew A, Riches DW, Albert RK, Douglas IS.SourceDivision of Pulmonary and Critical Care Medicine, Denver Health and University of Colorado, Department of Medicine, MC 4000, 777 Bannock Street, Denver, CO 80204. idouglas@dhha.org.
American journal of respiratory and critical care medicine.Am J Respir Crit Care Med.2012 Jul 1;186(1):72-81. Epub 2012 May 10.
Rationale: Mechanical ventilation induces heterogeneous lung injury by mitogen-activated protein kinase (MAPK) and nuclear factor-κB. Mechanisms regulating regional injury and protective effects of prone positioning are unclear. Objectives: To determine the key regulators of the lung regional prote
PMID 22582160

TIP30 loss enhances cytoplasmic and nuclear EGFR signaling and promotes lung adenocarcinogenesis in mice.

Li A, Zhang C, Gao S, Chen F, Yang C, Luo R, Xiao H.Source1] Department of Physiology, Michigan State University, East Lansing, MI, USA [2] Department of Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Oncogene.Oncogene.2012 Jun 25. doi: 10.1038/onc.2012.253. [Epub ahead of print]
Lung adenocarcinoma, the most common type of human non-small cell lung cancer (NSCLC), frequently overexpresses epidermal growth factor receptor (EGFR). However, the mechanisms underlying EGFR overexpression are not completely understood. Recent studies have identified that decreased expression of T
PMID 22733137

Japanese Journal

多彩な画像所見が腫瘍進展形式を示唆した置換性増殖優位型浸潤性肺腺癌の1例

日比野真,山本紗織,伊東直哉,平島修,大江元樹,近藤哲理
肺癌 54(4), 212-217, 2014
背景．置換性増殖優位型浸潤性腺癌は，以前は粘液非産生性細気管支肺胞上皮癌と呼ばれており，多彩な画像所見を呈する．症例．70歳の男性．7か月間の湿性咳嗽と1か月前からの労作時呼吸困難感を認めて受診した．胸部CTで広範囲に気管支透亮像を伴う浸潤影とメロンの皮様網目状陰影を認め，一部分に小葉中心性のすりガラス陰影を認めた．以上より経気道散布する病変が進行している状態が考えられ，経気管支肺生検の結果，置換 …
NAID 130004687682

Sunitinibによる間質性肺疾患の1例

関口善吉,滝沢明利,竹島徹平 [他]
泌尿器科紀要 58(9), 481-485, 2012-09
… Bronchioalveolar lavage showed a predominance of lymphocytes, without any evidence of infection. …
NAID 40019429492

両側多発すりガラス様陰影で発見された多発肺癌の1切除例

青山徹,前原孝光,安藤耕平,斎藤志子,益田宗孝
日本外科系連合学会誌 36(4), 600-604, 2011-08-30
　症例は76歳，女性.喫煙歴・アスベスト曝露歴はない．2002年から膵嚢胞性疾患で当院外科通院中であった．膵病変に対する術前検査で，胸部異常陰影を指摘され当科紹介受診となった．胸部CT検査で，左S1＋2，左S3（区域内に２カ所病変が存在），右S2に計４カ所のすりガラス様陰影（ground glass opacity:GGO）を認めた．CT上各病変の大きさは径19mm，26mm，15mm，18mmで …
NAID 10029684831

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