WordNet
- used to signify the Union forces in the American Civil War (who wore blue uniforms); "a ragged blue line"
- blue color or pigment; resembling the color of the clear sky in the daytime; "he had eyes of bright blue" (同)blueness
- any of numerous small butterflies of the family Lycaenidae
- blue clothing; "she was wearing blue"
- any organization or party whose uniforms or badges are blue; "the Union army was a vast blue"
- of the color intermediate between green and violet; having a color similar to that of a clear unclouded sky; "Octobers bright blue weather"- Helen Hunt Jackson; "a blue flame"; "blue haze of tobacco smoke" (同)bluish, blueish
- causing dejection; "a blue day"; "the dark days of the war"; "a week of rainy depressing weather"; "a disconsolate winter landscape"; "the first dismal dispiriting days of November"; "a dark gloomy day"; "grim rainy weather" (同)dark, dingy, disconsolate, dismal, gloomy, grim, sorry, drab, drear, dreary
- suggestive of sexual impropriety; "a blue movie"; "blue jokes"; "he skips asterisks and gives you the gamy details"; "a juicy scandal"; "a naughty wink"; "naughty words"; "racy anecdotes"; "a risque story"; "spicy gossip" (同)gamy, gamey, juicy, naughty, racy, risque, spicy
- morally rigorous and strict; "the puritan work ethic"; "puritanic distaste for alcohol"; "she was anything but puritanical in her behavior" (同)puritanic, puritanical
- turn blue
- garment consisting of a folded cloth drawn up between the legs and fastened at the waist; worn by infants to catch excrement (同)nappy, napkin
- a fabric (usually cotton or linen) with a distinctive woven pattern of small repeated figures
- a pattern of symptoms indicative of some disease
- a complex of concurrent things; "every word has a syndrome of meanings"
- a state of depression; "he had a bad case of the blues" (同)blue devils, megrims, vapors, vapours
- a type of folksong that originated among Black Americans at the beginning of the 20th century; has a melancholy sound from repeated use of blue notes
- a process that makes something blue (or bluish) (同)blueing
- used to whiten laundry or hair or give it a bluish tinge (同)blueing, blue
PrepTutorEJDIC
- 『青い』,あい色の / 青黒い / 《話》陰気な,憂うつな / 〈U〉『青色』,あい色;青色の着物 / 〈U〉〈C〉青色絵の具,あい色染料 / 《the~》《詩》青空,青い海 / 《the blues》《話》気のふさぎ,うれいの色 / 《the blues》《ときに単数扱い》(ジャズ音楽の)ブルース / …'を'青色にする
- 〈C〉《米》おしめ,おむつ(《英》nappy, napkin) / 〈U〉菱形模様;菱形地紋の麻布(タオル・ナプキン用) / 〈赤ん坊〉‘に'おむつを当てる
- (疾患の徴候となる一群の)症徴候,症候群 / (事件・社会的状態などのパターンを示す)徴候形態
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/09/15 22:43:14」(JST)
[Wiki en表示]
| Blue diaper syndrome |
| Classification and external resources |
| OMIM |
211000 |
| DiseasesDB |
33872 |
Blue diaper syndrome is a rare, autosomal recessive metabolic disorder characterized in infants by bluish urine-stained diapers.
It is caused by a defect in tryptophan absorption. Bacterial degradation of tryptophan in the intestine leads to excessive indole production and thus to indicanuria which, on oxidation to indigo blue, causes a peculiar bluish discoloration of the diaper. Symptoms typically include digestive disturbances, fever and visual problems.
It was characterized in 1964.[1]
Genetics
Blue diaper syndrome has an autosomal recessive pattern of inheritance.
Blue diaper syndrome is thought to be inherited as an autosomal recessive disorder.
Recent research indicates that mutations in the LAT2[2] and TAT1[3] genes might be involved in causing this syndrome
References
- ^ Drummond KN, Michael AF, Ulstrom RA, Good RA (1964). "The blue diaper syndrome: Familial hypercalcemia with nephrocalcinosis and indicanuria; A new familial disease, with definition of the metabolic abnormality". Am J Med 37 (6): 928–48. doi:10.1016/0002-9343(64)90134-2. PMID 14246093.
- ^ Park SY, Kim JK, Kim IJ, Choi BK, Jung KY, Lee S, Park KJ, Chairoungdua A, Kanai Y, Endou H, Kim do K (2005). "Reabsorption of neutral amino acids mediated by amino acid transporter LAT2 and TAT1 in the basolateral membrane of proximal tubule". Arch Pharm Res 28 (4): 421–32. doi:10.1007/BF02977671. PMID 15918515.
- ^ Kim do K, Kanai Y, Matsuo H, Kim JY, Chairoungdua A, Kobayashi Y, Enomoto A, Cha SH, Goya T, Endou H (2002). "The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location". Genomics 79 (1): 95–103. doi:10.1006/geno.2001.6678. PMID 11827462.
External links
- Blue diaper syndrome at NIH's Office of Rare Diseases
UpToDate Contents
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English Journal
- Reabsorption of neutral amino acids mediated by amino acid transporter LAT2 and TAT1 in the basolateral membrane of proximal tubule.
- Park SY, Kim JK, Kim IJ, Choi BK, Jung KY, Lee S, Park KJ, Chairoungdua A, Kanai Y, Endou H, Kim DK.SourceDepartment of Pediatrics, Kwangju Christian Hospital, Gwangju 503-715, Korea.
- Archives of pharmacal research.Arch Pharm Res.2005 Apr;28(4):421-32.
- In order to understand the renal reabsorption mechanism of neutral amino acids via amino acid transporters, we have isolated human L-type amino acid transporter 2 (hLAT2) and human T-type amino acid transporter 1 (hTAT1) in human, then, we have examined and compared the gene structures, the function
- PMID 15918515
- The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location.
- Kim DK, Kanai Y, Matsuo H, Kim JY, Chairoungdua A, Kobayashi Y, Enomoto A, Cha SH, Goya T, Endou H.SourceDepartment of Pharmacology and Toxicology, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka, Tokyo 181-8611, Japan.
- Genomics.Genomics.2002 Jan;79(1):95-103.
- System T is a Na+-independent transport system that selectively transports aromatic amino acids. Here, we determined the structure of the human T-type amino-acid transporter-1 (TAT1) cDNA and gene (SLC16A10). The human TAT1 cDNA encoded a 515-amino-acid protein with 12 putative membrane-spanning dom
- PMID 11827462
Japanese Journal
- 尿検査 インジカン (広範囲 血液・尿化学検査,免疫学的検査(第7版・1)その数値をどう読むか) -- (一般検査(尿・髄液・糞便検査を含む))
Related Links
- blue diaper syndrome Etymology: OFr, blou; ME, diapre, patterned fabric a defect of tryptophan absorption in which, because of intestinal bacterial action on the tryptophan, the urine contains abnormal indoles, giving it a blue color. It ...
- Blue diaper syndrome is a rare, genetic metabolic disorder characterized by the incomplete intestinal breakdown of tryptophan, a dietary nutrient. Symptoms typically include digestive disturbances, fever, irritability and visual ...
★リンクテーブル★
[★]
- 英
- blue diaper syndrome
- 同
- トリプトファン吸収不全症 tryptophan malabsorption syndrome
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- ダイヤパー
- ダイヤパーのナプキン/タオル。月経帯、ナプキン。(赤ん坊の)おむつ
- 菱形などの幾何学模様、寄せ木模様
[★]
- 関
- cyan
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