blepharochalasis

眼瞼皮膚弛緩症

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/08/31 12:13:19」(JST)

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Blepharochalasis
Classification and external resources
Specialty	ophthalmology
ICD-10	H02.3
ICD-9-CM	374.34

Blepharochalasis is an inflammation of the eyelid that is characterized by exacerbations and remissions of eyelid edema, which results in a stretching and subsequent atrophy of the eyelid tissue, leading to the formation of redundant folds over the lid margins. It typically affects only the upper eyelids, and may be unilateral as well as bilateral.

Pathophysiology

Blepharochalasis results from recurrent bouts of painless eyelid swelling, each lasting for several days. This is thought to be a form of localized angioedema, or rapid accumulation of fluid in the tissues. Recurrent episodes lead to thin and atrophic skin. Damage to the levator palpebrae superioris muscle causes ptosis, or drooping of the eyelid, when the muscle can no longer hold the eyelid up.

Causes

Blepharochalasis is idiopathic in most cases, i.e., the cause is unknown. Systemic conditions linked to blepharochalasis are renal agenesis, vertebral abnormalities, and congenital heart disease.

Epidemiology

It is encountered more commonly in younger rather than older individuals.

Complications

Complications of blepharochalasis may include conjunctival hyperemia (excessive blood flow through the moist tissues of the orbit), chemosis, entropion, ectropion, and ptosis.

Differential diagnosis

Dermatochalasis is sometimes confused with blepharochalasis, but these are two different conditions.

Treatment/Surgery

A surgeon trained to do eyelid surgery, such as a plastic surgeon or ophthalmologist, is required to decide and perform the appropriate surgical procedure. The following procedures have been described for blepharochalasis:

• External levator aponeurosis tuck
• Blepharoplasty
• Lateral canthoplasty
• Dermis fat grafts

These are used to correct atrophic blepharochalasis after the syndrome has run its course.

References

External links

• Review of Optometry handbook article on Blepharochalasis
• Picture of patient with Blepharochalasis
• BJO article abstract on Blepharochalasis

UpToDate Contents

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• 1. 血管浮腫の概要：臨床的特徴、診断、およびマネージメント an overview of angioedema clinical features diagnosis and management

English Journal

• Gender differences in the clinical course of Finnish gelsolin amyloidosis.

• Atula S1, Nikoskinen T2, Saastamoinen A2, Strbian D1, Schmidt EK2, Kiuru-Enari S1.
• Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.Amyloid.2016 Mar;23(1):33-8. doi: 10.3109/13506129.2015.1119111. Epub 2016 Jan 23.
• PURPOSE: To investigate gender differences in Finnish gelsolin amyloidosis (AGel amyloidosis).PATIENTS AND METHODS: AGel amyloidosis patients, who were members of Finnish Amyloidosis Association (SAMY), filled in a questionnaire compiling known and suspected aspects of their disease. Telephone inter
• PMID 26805765

• Blepharochalasis with double lip: A case of Ascher syndrome.

• Gupta V, Khandpur S1.
• Indian journal of dermatology, venereology and leprology.Indian J Dermatol Venereol Leprol.2015 Nov-Dec;81(6):651. doi: 10.4103/0378-6323.158645.
• PMID 26515861

• Blepharochalasis with double lip: A case of Ascher syndrome.

• Gupta V, Khandpur S1.
• Indian journal of dermatology, venereology and leprology.Indian J Dermatol Venereol Leprol.2015 Jun 18. doi: 10.4103/0378-6323.158645. [Epub ahead of print]
• PMID 26087089

Japanese Journal

• 眉毛下アプローチ (特集 眼瞼の美容外科 手術手技アトラス) -- (上眼瞼形成術)

• Pepars (87), 59-66, 2014-03
• NAID 40020032593

• 症例 若年男性眼瞼皮膚弛緩症の2例

• 形成外科 54(5), 541-546, 2011-05
• NAID 40018825074

• 東アジアにおける眉下切開による上眼瞼形成術

• 東京醫科大學雜誌 68(4), 367-371, 2010-10-30
• NAID 10027641829

Related Links

• Blepharochalasisとは - goo Wikipedia (ウィキペディア)

Blepharochalasis is an inflammation of the eyelid that is characterized by exacerbations and remissions of eyelid edema, which results in a stretching and subsequent atrophy of the eyelid tissue, leading to the formation of redundant ...

• Blepharochalasis Syndrome: Problem, Epidemiology, Etiology

Blepharochalasis is a rare syndrome consisting of recurrent bouts of upper eyelid edema associated with thinning, stretching, and fine wrinkling of the involved skin. The lower eyelids are not commonly involved.

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関

睫毛重生、眼瞼