- 関
- betamethasone、betamethasone butyrate propionate、betamethasone dipropionate、betamethasone sodium phosphate
WordNet
- a salt or ester of acetic acid (同)ethanoate
PrepTutorEJDIC
- 酢酸(さくさん)塩;アセテート(酢酸人造絹糸)
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2018/05/06 19:49:52」(JST)
[Wiki en表示]
Betamethasone acetate
|
Clinical data |
Drug class |
Corticosteroid; Glucocorticoid |
Identifiers |
IUPAC name
- (11,16β)-9-Fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl acetate
|
ChemSpider |
|
Chemical and physical data |
Formula |
C24H31FO6 |
Molar mass |
434.50 g·mol−1 |
3D model (JSmol) |
|
SMILES
-
C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)COC(=O)C)O)C)O)F)C
|
InChI
-
InChI=1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17-,18-,19-,21-,22-,23-,24-/m0/s1
-
Key:AKUJBENLRBOFTD-QZIXMDIESA-N
|
Betamethasone acetate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. It is the 21-acetate ester of betamethasone.[1]
References
- ^ "Betamethasone Sodium Phosphate and Betamethasone Acetate". drugs.com.
Glucocorticoid receptor modulators
|
GR |
Agonists |
- Cortisol-like and related (16-unsubstituted): 3α,5α-Tetrahydrocorticosterone
- 5α-Dihydrocorticosterone
- 9α-Fluorocortisone (alfluorone)
- 11-Dehydrocorticosterone (11-oxocorticosterone, 17-deoxycortisone)
- 11-Dehydrocorticosterone acetate
- 11-Deoxycorticosterone (desoxycortone, deoxycortone, desoxycorticosterone)
- 11-Deoxycortisol (cortodoxone, cortexolone)
- Cortifen (cortiphen, kortifen)
- Cortodoxone acetate
- 21-Deoxycortisol
- Δ7-Prednisolone
- Δ7-Prednisolone 21-acetate
- Amebucort
- Chloroprednisone
- Cloprednol
- Corticosterone
- Corticosterone acetate
- Corticosterone benzoate
- Cortisol (hydrocortisone)
- Benzodrocortisone (hydrocortisone benzoate)
- Hydrocortamate (hydrocortisone diethylaminoacetate)
- Hydrocortisone esters
- Cortisone
- Deprodone
- Dichlorisone
- Dichlorisone acetate
- Dichlorisone diacetate
- Difluprednate
- Endrisone (endrysone)
- Etiprednol
- Etiprednol dicloacetate (etiprednol dichloroacetate)
- Fludrocortisone (fludrocortone)
- Fluorometholone
- Fluperolone
- Fluprednisolone
- Halopredone
- Halopredone acetate (halopredone diacetate)
- Isoflupredone (9α-fluoroprednisolone)
- Loteprednol
- Mazipredone (depersolone)
- Medrysone
- Methylprednisolone
- Methylprednisolone esters
- Prebediolone
- Prednisolone
- Prednazate
- Prednazoline
- Prednicarbate (prednisolone ethylcarbonate propionate)
- Prednimustine
- Prednisolamate (prednisolone diethylaminoacetate)
- Prednisolone esters
- Prednisone
- Pregnenolone
- Pregnenolone acetate
- Pregnenolone succinate (pregnenolone hemisuccinate)
- Resocortol
- Tipredane
- Tixocortol
- Butixocort (tixocortol butyrate)
- Tixocortol pivalate
- Methasones and related (16-substituted): 16α-Methyl-11-oxoprednisolone
- Alclometasone
- Alclometasone dipropionate
- Amelometasone
- Beclometasone (beclomethasone)
- Betamethasone (betametasone)
- Betamethasone esters
- Cortobenzolone (betamethasone salicylate)
- Ciclometasone (ciclomethasone, cyclomethasone)
- Clobetasol
- Clobetasone
- Clocortolone
- Cloticasone
- Cormetasone (cormethasone)
- Descinolone
- Desoximetasone (desoxymethasone)
- Dexamethasone (dexametasone)
- Diflorasone
- Diflucortolone
- Diflucortolone pivalate
- Diflucortolone valerate
- Dimesone
- Doxibetasol (doxybetasol)
- Fluclorolone
- Flumetasone (flumethasone)
- Flumetasone acetate
- Flumetasone pivalate
- Fluocinolone
- Fluocortin
- Fluocortin butyl (fluocortin butylate)
- Fluocortolone
- Fluprednidene (fluprednylidene)
- Fluticasone
- Fluticasone furoate
- Fluticasone propionate
- Halocortolone
- Halometasone
- Icometasone
- Icometasone enbutate (icometasone butyrate acetate)
- Isoprednidene
- Locicortolone (locicortone)
- Locicortolone dicibate (locicortone dicibate)
- Meclorisone
- Meprednisone (methylprednisone)
- Meprednisone acetate
- Meprednisone hydrogen succinate (methylprednisone hemisuccinate)
- Mometasone
- Paramethasone
- Paramethasone acetate
- Paramethasone disodium phosphate
- Paramethasone phosphate
- Prednylidene
- Prednylidene diethylaminoacetate
- Rimexolone
- Ticabesone
- Timobesone
- Triamcinolone
- Ulobetasol (halobetasol)
- Vamorolone
- Cyclic ketals (16,17-cyclized): Acrocinonide (triamcinolone acroleinide)
- Amcinafal (triamcinolone pentanonide)
- Amcinafide (triamcinolone acetophenide)
- Amcinonide (triamcinolone acetate cyclopentanonide)
- Budesonide
- Ciclesonide
- Cicortonide
- Deflazacort (azacort)
- Descinolone acetonide
- Desonide (hydroxyprednisolone acetonide)
- Desonide disodium phosphate
- Desonide pivalate
- Dexbudesonide
- Drocinonide
- Fluazacort
- Fluclorolone acetonide (flucloronide)
- Fludroxycortide (flurandrenolone, flurandrenolide)
- Flumoxonide
- Flunisolide
- Fluocinolone acetonide
- Ciprocinonide (fluocinolone acetonide cyclopropylcarboxylate)
- Fluocinonide (fluocinolide, fluocinolone acetonide acetate)
- Procinonide (fluocinolone acetonide propionate)
- Formocortal
- Halcinonide
- Itrocinonide
- Rofleponide
- Tralonide
- Triamcinolone acetonide
- Flupamesone (triamcinolone acetonide metembonate)
- Triamcinolone acetonide esters
- Triamcinolone aminobenzal benzamidoisobutyrate (TBI-PAB)
- Triclonide
- Others/atypical (other expanded steroid ring systems, homosteroids, and non-pregnane steroids): Cortisuzol
- Cortivazol
- Domoprednate
- Naflocort
- Nicocortonide
- Nivacortol (nivazol)
- Oxisopred
- RU-28362
- Non-corticosteroids with some glucocorticoid activity: 15β-Hydroxycyproterone acetate
- 17α-Hydroxyprogesterone
- Chlormadinone acetate
- Cyproterone
- Cyproterone acetate
- Danazol
- Delmadinone acetate
- Desogestrel
- Etonogestrel
- Flugestone
- Flugestone acetate (flurogestone acetate)
- Fluoxymesterone
- Gestodene
- Medrogestone
- Medroxyprogesterone acetate
- Megestrol acetate
- Metribolone
- Norgestomet
- Osaterone acetate
- Progesterone
- Promegestone
- RU-2309
- Quingestrone
- Segesterone acetate (nestorone)
- Tetrahydrogestrinone
- Nonsteroidal glucocorticoids: AZD-5423
- GSK-9027
|
Mixed
(SEGRMs) |
- Dagrocorat
- Fosdagrocorat
- Mapracorat
|
Antagonists |
- 7α-Hydroxy-DHEA
- 17α-Methylprogesterone
- Aglepristone
- Asoprisnil
- Asoprisnil ecamate
- C108297
- C113176
- CORT-108297
- Cyproterone acetate
- Guggulsterone
- Ketoconazole
- Lilopristone
- LLY-2707
- Metapristone (RU-42633)
- Miconazole
- Mifepristone (RU-486)
- Onapristone
- ORG-34116
- ORG-34517 (SCH-900636)
- ORG-34850
- Pregnenolone 16α-carbonitrile
- Relacorilant (CORT-125134)
- RTI 3021–012
- RTI 3021–022
- Telapristone
- Tibolone
- Toripristone
- Ulipristal acetate
|
Others |
- Antisense oligonucleotides: IONIS-GCCRRx (ISIS-426115)
|
|
- See also
- Receptor/signaling modulators
- Glucocorticoids and antiglucocorticoids
- Mineralocorticoid receptor modulators
- List of corticosteroids
|
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- Annoying Hiccups following Intra-Articular Corticosteroid Injection of Betamethasone Acetate/Betamethasone Sodium Phosphate at the Knee Joint.
- Habib G, Artul S, Hakim G.SourceRheumatology Clinic, Nazareth Hospital, 16000 Nazareth, Israel ; Department of Medicine, Carmel Medical Center, 34362 Haifa, Israel.
- Case reports in rheumatology.Case Rep Rheumatol.2013;2013:829620. doi: 10.1155/2013/829620. Epub 2013 Mar 14.
- Hiccups is a type of reflex that could happen secondary to different causes including drugs, especially systemic corticosteroids. Usually, high rather than regular doses of systemic steroids are incriminated, and this could explain the fact that very few cases of hiccups following regional corticost
- PMID 23573452
- [Antiinflammatory potential of seven plant extracts in the ultraviolet erythema test. A randomized, placebo-controlled study].
- Beikert FC, Schönfeld BS, Frank U, Augustin M.SourceIVDP - Institut für Versorgungsforschung in der Dermatologie und bei Pflegeberufen, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Deutschland. f.beikert@uke.de
- Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete.Hautarzt.2013 Jan;64(1):40-6. doi: 10.1007/s00105-012-2505-x.
- BACKGROUND: Phytotherapeutics are widely used in medicine. The aim of this study was the evaluation of the antiinflammatory potential of seven medical plant extracts using the ultraviolet- (UV)-erythema test.PATIENTS AND METHODS: Randomized, placebo-controlled study on 40 healthy subjects. Test area
- PMID 23337964
- Efficacy comparisons of the intraarticular steroidal agents in the patients with knee osteoarthritis.
- Yavuz U, Sökücü S, Albayrak A, Oztürk K.SourceBaltalimani Bone Diseases Training and Research Hospital, Istanbul, Turkey. umut78@yahoo.com
- Rheumatology international.Rheumatol Int.2012 Nov;32(11):3391-6. doi: 10.1007/s00296-011-2188-0. Epub 2011 Nov 5.
- Osteoarthritis is a chronic disease that causes serious pain and limitations in activities. Intraarticular corticosteroid injections combined with pharmacological treatment and physiotherapy have been used for years to control the local inflammation and relieve pain in the patients with osteoarthrit
- PMID 22057944
Japanese Journal
- Determination of Selected Corticosteroids in Sewage-treatment-plant Samples by Liquid Chromatography-mass Spectrometry
- Kitaichi Yuko,Miyamoto Aoi,Uchikura Kazuo
- JOURNAL OF HEALTH SCIENCE 56(5), 547-556, 2010
- … The compounds studied were prednisolone, dexamethasone, betamethasone, triamcinolone acetonide, fluocinolone acetonide, prednisolone acetate, hydrocortisone acetate, betamethasone valerate, and betamethasone dipropionate. …
- NAID 130000425090
- Suppression of Laser-Induced Choroidal Neovascularization by Subconjunctival Injection of 9α-Fluoromedroxyprogesterone Acetate (FMPA), an Anti-angiogenic Agent, in Rats(Pharmacology)
- MURATA Natsuko,YAMAJI Taketo,UCHIDA Masayuki,TSUBOI Hiroshi,SUZUKI Hiroto,YAMADA Masashi,OIKAWA Tsutomu,NOBUHIRO Junko,CHOSHI Tominari,HIBINO Satoshi
- Biological & pharmaceutical bulletin 29(12), 2410-2414, 2006-12-01
- … 9α-Fluoromedroxyprogesterone acetate (FMPA) is a synthetic analog of medroxyprogesterone acetate (MPA). … Anecortave acetate, an angiostatic steroid, is clinically efficacious in patients with exudative AMD. … Betamethasone is an anti-angiogenic steroid. … Therefore, we examined the effects of FMPA, anecortave acetate and betamethasone on laser-induced CNV in rats. …
- NAID 110006148662
Related Links
- Betamethasone Sodium Phosphate and Betamethasone Acetate official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more. ... Indications and Usage for ...
- Treatment by Condition Related to betamethasone acetate and sodium phosphate injection Inflammation of the Nose due to an Allergy Medications Bronchitis Medications Crohn's Disease Medications Rheumatoid Arthritis ...
★リンクテーブル★
[★]
- 英
- betamethasone
- 同
- ベタメサゾン
- 化
- ベタメタゾンリン酸エステルナトリウム、リン酸ベタメタゾンナトリウム betamethasone sodium phosphate
- 酢酸ベタメタゾン betamethasone acetate
- 吉草酸ベタメタゾン betamethasone valerate。ベタメタゾン吉草酸エステル
- ベタメタゾンジプロピオン酸エステル、ジプロピオン酸ベタメタゾン betamethasone dipropionate
- ベタメタゾン酪酸エステルプロピオン酸エステル
- 商
- リンデロン Rinderon、アンテベート。Celestone
- アンテベート、アンフラベート、エンペラシン、ケリグロール、サクコルチン、サレックス、サンベタゾン、ステロネマ、セレスタミン、ダイプロセル、ディーピーポロン、デキサンVG、デルモゾールDP、デルモゾールG、デルモゾール、トクダーム、トチプロベタゾン、ノルコット、ハイコート、ヒスタブロック、ヒズボット、フロダーム、プラデスミン、ベクトミラン、ベタセレミン、ベトネベートN、ベトネベート、ベトノバールG、ベルベゾロンF、ベルベゾロン、リダスロン、リネステロン、リノロサール、リンデロン-DP、リンデロン-VG、リンデロン-V、リンデロン、リンベタPF、ルリクールVG、リンデロンA
- 関
- 鎮痛,鎮痒,収歛,消炎剤
GOO.1594
Table 59–2 Relative Potencies and Equivalent Doses of Representative Corticosteroids
|
COMPOUND
|
ANTIINFLAMMATORY POTENCY
|
Na+-RETAINING POTENCY
|
DURATION OF ACTION
|
EQUIVALENT DOSE, MG
|
prednisone
|
4
|
0.8
|
I
|
5
|
prednisolone
|
4
|
0.8
|
I
|
5
|
betamethasone
|
25
|
0
|
L
|
0.75
|
dexamethasone
|
25
|
0
|
L
|
0.75
|
[★]
- 関
- betamethasone、betamethasone 17-valerate、betamethasone acetate、betamethasone butyrate propionate、betamethasone sodium phosphate
[★]
- 関
- betamethasone、betamethasone 17-valerate、betamethasone acetate、betamethasone butyrate propionate、betamethasone dipropionate
[★]
- 関
- betamethasone、betamethasone acetate、betamethasone dipropionate、betamethasone sodium phosphate
[★]
- 英
- betamethasone acetate
- 関
- ベタメタゾン