Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/05/15 00:50:15」(JST)

Benproperine (INN) is a cough suppressant.^[1]

References

^ Li, Y.; Zhong, D. F.; Chen, S. W.; Maeba, I. (2005). "Identification of some benproperine metabolites in humans and investigation of their antitussive effect1". Acta Pharmacologica Sinica 26 (12): 1519–1526. doi:10.1111/j.1745-7254.2005.00212.x. PMID 16297353. edit

This drug article relating to the respiratory system is a stub. You can help Wikipedia by expanding it.

Resonance light scattering study on the interaction of benproperine phosphate with eriochrome blue black R in the presence of sodium dodecylbenzene sulphonate and its analytical application.

Feng S1, Liu J, Han X, Fan J.
Luminescence : the journal of biological and chemical luminescence.Luminescence.2009 Mar-Apr;24(2):67-72. doi: 10.1002/bio.1064.
The interaction of benproperine phosphate (BPP) with eriochrome blue black R (EBBR) in the presence of sodium dodecylbenzene sulphonate (SDBS) was studied using resonance light scattering (RLS) technology and ultraviolet-visual (UV-vis) spectrophotometry. Under optimum conditions, BPP reacts with EB
PMID 18800357

[Nondestructive quantitative analysis of Cofrel medicines by improved partial least squares-NIR spectroscopy].

Liu MY1, Meng Y, Ren YL, Zhang HQ.
Guang pu xue yu guang pu fen xi = Guang pu.Guang Pu Xue Yu Guang Pu Fen Xi.2007 Jun;27(6):1098-101.
In the present paper, improved partial least squares (PLS) method was used to parse near infrared (NIR) reflectance spectrum of Cofrel medicine. The contents of benproperine phosphate, a availability pharmaceutical in Cofrel medicine, were accurately nondestructively quantitatively predicted. The be
PMID 17763766

Identification and quantitative determination of benproperine metabolites in human plasma and urine by liquid chromatography-tandem mass spectrometry.

Li Y1, Sun Y, Dong Y, Zhang Y, Zhong D.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.J Chromatogr B Analyt Technol Biomed Life Sci.2006 Jan 2;830(1):71-80. Epub 2005 Nov 8.
Two novel metabolites of benproperine (BPP), 1-[1-methyl-2-[2-(phenylmethyl)phenoxy]ethyl]-3-piperidinol (3-OH-BPP) and 1-[1-methyl-2-[2-(phenylmethyl)phenoxy]ethyl]-4-piperidinol (4-OH-BPP), were confirmed by comparison of retention times and mass spectra with those of synthetic standards using liq
PMID 16280263

Identification and quantitative determination of benproperine metabolites in human plasma and urine by liquid chromatography-tandem mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 830(1), 71-80, 2006-01-02
NAID 10025777814

リンク元	「ベンプロペリン」
拡張検索	「benproperine phosphate」

Benproperine
Systematic (IUPAC) name
	(RS)-1-[2-(2-benzylphenoxy)-1-methylethyl]piperidine
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Registry Number	2156-27-6 19428-14-9 (phosphate salt)
ATC code	R05DB02
PubChem	CID 2326
ChemSpider	2236
UNII	3AA6IZ48YK
KEGG	D07512
ChEMBL	CHEMBL2105910
Chemical data
Formula	C21H27NO
Molecular mass	309.445 g/mol
	SMILES O(c1ccccc1Cc2ccccc2)CC(N3CCCCC3)C;
	InChI InChI=1S/C21H27NO/c1-18(22-14-8-3-9-15-22)17-23-21-13-7-6-12-20(21)16-19-10-4-2-5-11-19/h2,4-7,10-13,18H,3,8-9,14-17H2,1H3 ; Key:JTUQXGZRVLWBCR-UHFFFAOYSA-N ;
(what is this?) (verify)