好塩基球減少症
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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/12/11 13:31:44」(JST)
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Basopenia |
Classification and external resources |
Specialty |
hematology |
ICD-10 |
D72.8 |
ICD-9-CM |
288.59 |
Basopenia (or basocytopenia) is a form of agranulocytosis associated with a deficiency of basophils.[1]
One cause is urticaria.[2][3][4]
It has been proposed as an indicator of ovulation.[5]
It is difficult to detect without flow cytometry, because normal levels are so low.[6]
It can be defined as less than 0.01 x 10−9 / L.[7]
References
- ^ "Definition: basophilic leukopenia from Online Medical Dictionary".
- ^ Lourenço FD, Azor MH, Santos JC (May 2008). "Activated status of basophils in chronic urticaria leads to interleukin-3 hyper-responsiveness and enhancement of histamine release induced by anti-IgE stimulus". Br. J. Dermatol. 158 (5): 979–86. doi:10.1111/j.1365-2133.2008.08499.x. PMID 18341658.
- ^ Grattan CE, Dawn G, Gibbs S, Francis DM (March 2003). "Blood basophil numbers in chronic ordinary urticaria and healthy controls: diurnal variation, influence of loratadine and prednisolone and relationship to disease activity". Clin. Exp. Allergy 33 (3): 337–41. doi:10.1046/j.1365-2222.2003.01589.x. PMID 12614448.
- ^ Grattan CE, Walpole D, Francis DM (December 1997). "Flow cytometric analysis of basophil numbers in chronic urticaria: basopenia is related to serum histamine releasing activity". Clin. Exp. Allergy 27 (12): 1417–24. doi:10.1111/j.1365-2222.1997.tb02986.x. PMID 9433937.
- ^ Soni R, Bose S, Gada D, Potnis V (October 1996). "Basopenia as an indicator of ovulation (a short term clinical study)". Indian J. Physiol. Pharmacol. 40 (4): 385–8. PMID 9055113.
- ^ "CLS_3223_Unit 03_WBC".
- ^ "Pathology".
Hematologic disease: Monocyte and granulocyte disease (CFU-GM/CFU-Baso/CFU-Eos), including immunodeficiency (D70-D71, 288)
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Monocytes/
macrophages |
↑ |
- Histiocytosis
- Chronic granulomatous disease
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-cytosis: |
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↓ |
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Granulocytes |
↑ |
-cytosis: |
- granulocytosis
- Neutrophilia
- Eosinophilia/Hypereosinophilic syndrome
- Basophilia
- Bandemia
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↓ |
-penia: |
- Granulocytopenia/agranulocytosis (Neutropenia/Kostmann syndrome
- Eosinopenia
- Basopenia)
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PBD |
chemotaxis/degranulation: |
- Leukocyte adhesion deficiency
- Chédiak–Higashi syndrome
- Neutrophil-specific granule deficiency
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respiratory burst: |
- Chronic granulomatous disease
- Neutrophil immunodeficiency syndrome
- Myeloperoxidase deficiency
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Index of cells from bone marrow
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Description |
- Immune system
- Cells
- Physiology
- coagulation
- proteins
- granule contents
- colony-stimulating
- heme and porphyrin
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Disease |
- Red blood cell
- Monocyte and granulocyte
- Neoplasms and cancer
- Histiocytosis
- Symptoms and signs
- Blood tests
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Treatment |
- Transfusion
- Drugs
- thrombosis
- bleeding
- other
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English Journal
- Interval shifts in basophil measures correlate with disease activity in chronic spontaneous urticaria.
- Oliver ET1, Sterba PM, Saini SS.
- Allergy.Allergy.2015 May;70(5):601-3. doi: 10.1111/all.12578. Epub 2015 Mar 16.
- Chronic spontaneous urticaria (CSU) significantly impacts the quality of life of those affected through symptoms of pruritus and recurrent skin lesions. In active CSU disease, reduced IgE-mediated basophil histamine release (HR) and basopenia are observed. We sought to examine the relationship betwe
- PMID 25631394
- Clinical-laboratory characteristics of ANA-positive chronic idiopathic urticaria.
- Magen E1, Waitman DA, Dickstein Y, Davidovich V, Kahan NR.
- Allergy and asthma proceedings : the official journal of regional and state allergy societies.Allergy Asthma Proc.2015 Mar-Apr;36(2):138-44. doi: 10.2500/aap.2015.36.3829.
- Despite the established association between chronic idiopathic/spontaneous urticaria (CIU) and presence of antinuclear antibodies (ANAs), the prevalence of autoimmune comorbidities in this population has not been analyzed. Here, we aim to identify clinical and laboratory manifestations associated wi
- PMID 25715242
- Immunological events in chronic spontaneous urticaria.
- Ferrer M1.
- Clinical and translational allergy.Clin Transl Allergy.2015 Aug 25;5:30. doi: 10.1186/s13601-015-0074-7. eCollection 2015.
- Chronic spontaneous urticaria (CSU) is a highly debilitating skin disease associated with systemic features. We have made significant progress in several aspects relating to this condition. However, the exact physiopathology remains unknown. There is mounting evidence for an autoimmune basis, demons
- PMID 26309723
Related Links
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