出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/08/21 19:43:07」(JST)
Basilar invagination is invagination (infolding) of the base of the skull that occurs when the top of the C2 vertebra migrates upward. It can cause narrowing of the foramen magnum (the opening in the skull where the spinal cord passes through to the brain). It also may press on the lower brainstem.[1]
This is similar to Chiari malformation. That, however, is usually present at birth.
Symptoms vary depending on whether the spinal cord, brain stem, nerves or their blood supply is affected by the pressure.
Symptoms become apparent when the neck is bent. They include:
Complications from this can include hydrocephalus, pseudotumor cerebri or syringomyelia because it blocks the flow of fluid around the brain and spinal cord.
Basilar invagination can be present at birth. If the condition develops after birth, it is usually the result of injury or diseases. If due to injury, about half the time it is caused by vehicle or bicycle accidents; 25% of the time by falls and 10% of the time by recreational activities such as diving accidents.
It also occurs in patients with bone diseases, such as osteomalacia, rheumatoid arthritis, Paget's disease, Ehlers-Danlos syndrome, Marfan syndrome, and osteogenesis imperfecta.
A doctor will base his or her diagnosis on the symptoms the patient has and the results of tests, including:
If there aren't neurological symptoms (such as difficulties moving, loss of sensation, confusion, etc.) and there is no evidence of pressure on the spinal cord, a conservative approach may be taken such as:
If there is pressure on the spinal cord or life-threatening symptoms are present, surgery is recommended.
Congenital malformations and deformations of nervous system (Q00–Q07, 740–742)
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| リンク元 | 「頭蓋底陥入症」 |
| 関連記事 | 「basilar」「invagination」「basil」 |